Articles
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Citation: Journal of Intensive Care 2024 12:25
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Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation
There is no reliable indicator that can assess the treatment effect of anticoagulant therapy for sepsis-associated disseminated intravascular coagulation (DIC) in the short term. The aim of this study is to de...
Citation: Journal of Intensive Care 2024 12:24 -
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients
Difficult-to-wean patients, typically identified as those failing the initial spontaneous breathing trial (SBT), face elevated mortality rates. Pendelluft, frequently observed in patients experiencing SBT fail...
Citation: Journal of Intensive Care 2024 12:23 -
Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study
In out-of-hospital cardiac arrest (OHCA) patients with extracorporeal cardiopulmonary resuscitation (ECPR), the association between low-flow time and outcomes in accidental hypothermia (AH) patients compared t...
Citation: Journal of Intensive Care 2024 12:22 -
Hospital and regional variations in intensive care unit admission for patients with invasive mechanical ventilation
Patients who receive invasive mechanical ventilation (IMV) in the intensive care unit (ICU) have exhibited lower in-hospital mortality rates than those who are treated outside. However, the patient-, hospital-...
Citation: Journal of Intensive Care 2024 12:21 -
Case volume and specialization in critically ill emergency patients: a nationwide cohort study in Japanese ICUs
Previous studies have explored the association between the number of cases and patient outcomes for critical illnesses such as sepsis and trauma, as well as various surgeries, with the expectation that a highe...
Citation: Journal of Intensive Care 2024 12:20 -
Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling
To optimize right ventricular–pulmonary coupling during veno-arterial (VA) ECMO weaning, inotropes, vasopressors and/or vasodilators are used to change right ventricular (RV) function (contractility) and pulmo...
Citation: Journal of Intensive Care 2024 12:19 -
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium
Extracorporeal membrane oxygenation (ECMO) is a rescue therapy in patients with severe acute respiratory distress syndrome (ARDS) secondary to COVID-19. While bleeding and thrombosis complicate ECMO, these eve...
Citation: Journal of Intensive Care 2024 12:18 -
Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients
Recent advances on cardiorespiratory monitoring applied in ARDS patients undergoing invasive mechanical ventilation and noninvasive ventilatory support are available in the literature and may have potential pr...
Citation: Journal of Intensive Care 2024 12:17 -
Prognostic nutritional index as a predictive marker for acute kidney injury in adult critical illness population: a systematic review and diagnostic test accuracy meta-analysis
The prognostic nutritional index (PNI), integrating nutrition and inflammation markers, has been increasingly recognized as a prognostic predictor in diverse patient cohorts. Recently, its effectiveness as a p...
Citation: Journal of Intensive Care 2024 12:16 -
Respiratory drive: a journey from health to disease
Respiratory drive is defined as the intensity of respiratory centers output during the breath and is primarily affected by cortical and chemical feedback mechanisms. During the involuntary act of breathing, ch...
Citation: Journal of Intensive Care 2024 12:15 -
The optimal glycemic target in critically ill patients: an updated network meta-analysis
Acute glycemic control significantly affects the clinical outcomes of critically ill patients. This updated network meta-analysis examines the benefits and harms of four target blood glucose levels (< 110, 110...
Citation: Journal of Intensive Care 2024 12:14 -
Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study
Clinical practice guidelines on limitation of life-sustaining treatments (LST) in the intensive care unit (ICU), in the form of withholding or withdrawal of LST, state that there is no ethical difference betwe...
Citation: Journal of Intensive Care 2024 12:13 -
Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial
Arterial catheters (ACs) are critical for haemodynamic monitoring and blood sampling but are prone to complications. We investigated the incidence and risk factors of AC failure.
Citation: Journal of Intensive Care 2024 12:12 -
From bedside to recovery: exercise therapy for prevention of post-intensive care syndrome
As advancements in critical care medicine continue to improve Intensive Care Unit (ICU) survival rates, clinical and research attention is urgently shifting toward improving the quality of survival. Post-Inten...
Citation: Journal of Intensive Care 2024 12:11 -
Unit-to-unit transfer due to shortage of intensive care beds in Sweden 2015–2019 was associated with a lower risk of death but a longer intensive care stay compared to no transfer: a registry study
Intensive care unit-to-unit transfer due to temporary shortage of beds is increasing in Sweden. Transportation induces practical hazards, and the change of health care provider may prolong the length of stay i...
Citation: Journal of Intensive Care 2024 12:10 -
Exploring the therapeutic role of early heparin administration in ARDS management: a MIMIC-IV database analysis
Acute respiratory distress syndrome (ARDS) is a severe respiratory condition characterized by a high mortality rate, the management of which relies on supportive care and a profound understanding of its pathop...
Citation: Journal of Intensive Care 2024 12:9 -
Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study
Patients with sepsis-associated encephalopathy (SAE) have higher mortality rates and longer ICU stays. Predictors of SAE are yet to be identified. We aimed to establish an effective and simple-to-use nomogram ...
Citation: Journal of Intensive Care 2024 12:8 -
External validation of the HACOR score and ROX index for predicting treatment failure in patients with coronavirus disease 2019 pneumonia managed on high-flow nasal cannula therapy: a multicenter retrospective observational study in Japan
The HACOR score for predicting treatment failure includes vital signs and acid–base balance factors, whereas the ROX index only considers the respiratory rate, oxygen saturation, and fraction of inspired oxyge...
Citation: Journal of Intensive Care 2024 12:7 -
Association between regional critical care capacity and the incidence of invasive mechanical ventilation for coronavirus disease 2019: a population-based cohort study
Coronavirus disease 2019 (COVID-19) has exposed critical care supply shortages worldwide. This study aimed to investigate the association between regional critical care capacity and the incidence of invasive m...
Citation: Journal of Intensive Care 2024 12:6 -
Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry
Chest computed tomography findings are helpful for understanding the pathophysiology of severe acute respiratory distress syndrome (ARDS). However, there is no large, multicenter, chest computed tomography reg...
Citation: Journal of Intensive Care 2024 12:5 -
Efficacy of permissive underfeeding for critically ill patients: an updated systematic review and trial sequential meta-analysis
Our previous study in 2011 concluded that permissive underfeeding may improve outcomes in patients receiving parenteral nutrition therapy. This conclusion was tentative, given the small sample size. We conduct...
Citation: Journal of Intensive Care 2024 12:4 -
Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive
The limitation of life sustaining treatments (LLST) causes ethical dilemmas even in patients faced with poor prognosis, which applies to many patients admitted to a Neurocritical Care Unit (NCCU). The effects ...
Citation: Journal of Intensive Care 2024 12:3 -
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review
Post-intensive care syndrome (PICS) is the long-lasting impairment of physical functions, cognitive functions, and mental health after intensive care. Although a long-term follow-up is essential for the succes...
Citation: Journal of Intensive Care 2024 12:2 -
Development of quality indicators for palliative care in intensive care units and pilot testing them via electronic medical record review
Patients in intensive care units (ICUs) often require quality palliative care for relief from various types of suffering. To achieve quality palliative care, specific goals need to be identified, measured, and...
Citation: Journal of Intensive Care 2024 12:1 -
Mechanical circulatory support in cardiogenic shock
Cardiogenic shock is a complex and diverse pathological condition characterized by reduced myocardial contractility. The goal of treatment of cardiogenic shock is to improve abnormal hemodynamics and maintain ...
Citation: Journal of Intensive Care 2023 11:64 -
Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort
Extra-hepatic vitamin K-status, measured by dephosphorylated uncarboxylated matrix Gla protein (dp-ucMGP), maintains vascular health, with high levels reflecting poor vitamin K status. The occurrence of extra-...
Citation: Journal of Intensive Care 2023 11:63 -
Functional intervention following cardiac surgery to prevent postoperative delirium in older patients (FEEL WELL study)
Postoperative delirium is a common complication in patients after cardiac surgery, especially in older patients, and can manifest as a disturbance of attention and consciousness. It can lead to increased posto...
Citation: Journal of Intensive Care 2023 11:62 -
Light and dark sides of evidence-based and supportive ICU care for patients undergoing extracorporeal membrane oxygenation
Citation: Journal of Intensive Care 2023 11:61 -
Intensive care unit mortality and cost-effectiveness associated with intensivist staffing: a Japanese nationwide observational study
Japan has four types of intensive care units (ICUs) that are divided into two categories according to the management fee charged per day: ICU management fees 1 and 2 (ICU1/2) (equivalent to high-intensity staf...
Citation: Journal of Intensive Care 2023 11:60 -
Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study
Heterogeneity among critically ill patients undergoing invasive mechanical ventilation (IMV) treatment could result in high mortality rates. Currently, there are no well-established indicators to help identify...
Citation: Journal of Intensive Care 2023 11:59 -
Visualizing the dynamic mechanical power and time burden of mechanical ventilation patients: an analysis of the MIMIC-IV database
Limiting driving pressure and mechanical power is associated with reduced mortality risk in both patients with and without acute respiratory distress syndrome. However, it is still poorly understood how the in...
Citation: Journal of Intensive Care 2023 11:58 -
Optimized ventilation power to avoid VILI
The effort to minimize VILI risk must be multi-pronged. The need to adequately ventilate, a key determinant of hazardous power, is reduced by judicious permissive hypercapnia, reduction of innate oxygen demand...
Citation: Journal of Intensive Care 2023 11:57 -
The optimal dose of mobilisation therapy in the ICU: a prospective cohort study
This study aimed to assess the impact of duration of early mobilisation on survivors of critical illness. The hypothesis was that interventions lasting over 40 min, as per the German guideline, positively affe...
Citation: Journal of Intensive Care 2023 11:56 -
Prolonged use of neuromuscular blocking agents is associated with increased long-term mortality in mechanically ventilated medical ICU patients: a retrospective cohort study
Neuromuscular blockade agents (NMBAs) can be used to facilitate mechanical ventilation in critically ill patients. Accumulating evidence has shown that NMBAs may be associated with intensive care unit (ICU)-ac...
Citation: Journal of Intensive Care 2023 11:55 -
Variation in coagulation factor activity levels cause discrepancies between activated partial thromboplastin time and anti-Xa activity for heparin monitoring: a retrospective observational study
Unfractionated heparin (UFH) is primarily monitored using activated partial thromboplastin time (APTT). However, the recent introduction of anti-activated factor X (anti-Xa) activity testing has provided a dir...
Citation: Journal of Intensive Care 2023 11:54 -
Translation of patients’ advance directives in intensive care units: are we there yet?
This review examined studies regarding the implementation and translation of patients’ advance directives (AD) in intensive care units (ICUs), focusing on practical difficulties and obstacles.
Citation: Journal of Intensive Care 2023 11:53 -
Concerns with the revised Japanese recommendation for administering vitamin C to septic patients
Citation: Journal of Intensive Care 2023 11:52 -
Efficacy, safety, and pharmacokinetics of MR13A11A, a generic of remifentanil, for pain management of Japanese patients in the intensive care unit: a double-blinded, fentanyl-controlled, randomized, non-inferiority phase 3 study
The aims of this study were to evaluate the efficacy, safety, and pharmacokinetics (PK) of continuous intravenous administration of remifentanil in mechanically ventilated patients in the intensive care unit (...
Citation: Journal of Intensive Care 2023 11:51 -
Lacosamide dosing in patients receiving continuous renal replacement therapy
Lacosamide is one of the anticonvulsants used in critically ill patients. This study aimed to suggest appropriate lacosamide dosing regimens in critically ill patients receiving continuous renal replacement th...
Citation: Journal of Intensive Care 2023 11:50 -
A deep learning model for predicting multidrug-resistant organism infection in critically ill patients
This study aimed to apply the backpropagation neural network (BPNN) to develop a model for predicting multidrug-resistant organism (MDRO) infection in critically ill patients.
Citation: Journal of Intensive Care 2023 11:49 -
Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials
The efficacy of therapeutic drug monitoring (TDM)-based antimicrobial dosing optimization strategies on pharmacokinetics/pharmacodynamics and specific drug properties for critically ill patients is unclear. He...
Citation: Journal of Intensive Care 2023 11:48 -
Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023)
Providing standardized, high-quality rehabilitation for critically ill patients is a crucial issue. In 2017, the Japanese Society of Intensive Care Medicine (JSICM) promulgated the “Evidence-Based Expert Conse...
Citation: Journal of Intensive Care 2023 11:47 -
Trends in massive transfusion practice for trauma in Japan from 2011 to 2020: a nationwide inpatient database study
Previous studies have reported conflicting results regarding fresh frozen plasma (FFP)-to-red blood cell (RBC) ratio and platelet-to-RBC ratio on outcomes for massive transfusion for trauma. Moreover, nationwi...
Citation: Journal of Intensive Care 2023 11:46 -
Polymyxin B-immobilised fibre column treatment for acute exacerbation of idiopathic pulmonary fibrosis patients with mechanical ventilation: a nationwide observational study
The prognosis for acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is poor, and there is no established treatment. Hence, we aimed to investigate the effectiveness of a polymyxin B-immobilised fibr...
Citation: Journal of Intensive Care 2023 11:45 -
Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?
While not traditionally included in the conceptual understanding of circulation, the interstitium plays a critical role in maintaining fluid homeostasis. Fluid balance regulation is a critical aspect of septic...
Citation: Journal of Intensive Care 2023 11:44 -
Long-term prognostic significance of gasping in out-of-hospital cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation: a post hoc analysis of a multi-center prospective cohort study
Gasping during resuscitation has been reported as a favorable factor for out-of-hospital cardiac arrest. We examined whether gasping during resuscitation is independently associated with favorable neurological...
Citation: Journal of Intensive Care 2023 11:43 -
High driving pressure ventilation induces pulmonary hypertension in a rabbit model of acute lung injury
Mechanical ventilation may cause pulmonary hypertension in patients with acute lung injury (ALI), but the underlying mechanism remains elucidated.
Citation: Journal of Intensive Care 2023 11:42 -
A novel method for diaphragm-based electrode belt position of electrical impedance tomography by ultrasound
This aim of study was to introduce a diaphragm-based EIT-belt placement method based on diaphragm position by ultrasound, and to evaluate the difference between diaphragm-based EIT-belt placement and conventio...
Citation: Journal of Intensive Care 2023 11:41 -
Ultrasonographic evaluation of the diaphragm in critically ill patients to predict invasive mechanical ventilation
Diaphragm dysfunction is common in critically ill patients and associated with poorer outcomes. The function of the diaphragm can be evaluated at the bedside by measuring diaphragmatic excursion using ultrason...
Citation: Journal of Intensive Care 2023 11:40
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- ISSN: 2052-0492 (electronic)