[Featured Review] Practical approach to detection and management of acute kidney injury in critically ill patient

AKI0210Acute kidney injury (AKI) is common in critically ill patients and is associated with high mortality. Vahid Mohsenin's review provides the etiologies of AKI and a systematic approach toward its diagnosis and management with emphasis on fluid volume assessment and urine biochemical profile.


[Featured article] Clinical significance of measuring plasminogen activator inhibitor-1 in sepsis (Commentary)

inhibitor-1 0210Disseminated thrombosis in the microcirculation is an important cause of multiple organ dysfunction in sepsis. The purpose of this prothrombotic change is the host defense against microbial dissemination. In that process, antifibrinolytic property by PAI-1 plays an important role.

See this article by Toshiaki Iba and Jecko Thachil

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Society affiliation

Journal of Intensive Care is the official journal of the Japanese Society of Intensive Care Medicine (JSICM).

The publication costs for Journal of Intensive Care are currently covered by JSICM, therefore no fees will be charged to authors whose articles are accepted for publication in the journal.

Featured series

Current overview in pediatric critical care
In this thematic series, the authors review the current management of pediatric sepsis, pediatric organ transplantation, pediatric cardiac surgery and more.

Trauma-induced coagulopathy and critical bleeding
In this thematic series, the authors examine the pathophysiology of trauma-induced coagulopathy and discuss the novel therapeutic strategies for the management of patients with severe trauma.

Point-of-care ultrasound
In this thematic series, the authors review various clinical studies on point-of-care ultrasound, which were carried out based on the ideas of “extraction”, “creation” and “integration”.

Organ dysfunction in sepsis
In this thematic series, the authors review the pathophysiology of organ dysfunction in sepsis. The role of two main pathomechanisms of organ dysfunction, DIC and endothelial cell dysfunction, are also discussed.

Neurocritical care
In this thematic series, the role of monitoring is highlighted to guide the treatment and therapeutic intervention tailored for the pathophysiologic degree of brain injury.

Fluid management
In this thematic series, the principal and practical matters underlying fluid therapy are highlighted to allow intensivists around the world to better understand and manage such primary and consistent intervention as fluid therapy in critically ill patients.

Editors' profiles

Satoshi Gando, Editor-in-Chief

Dr Satoshi Gando is currently a Professor and Chairman of the Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine at the Hokkaido University Graduate School of Medicine, Sapporo, Japan. He is also Director of the Critical Center, which includes the emergency room and intensive care unit at Hokkaido University Hospital.

Hiroshi Morisaki, Deputy Editor

Dr Hiroshi Morisaki is currently Professor and Chair of the Department of Anesthesiology at Keio University School of Medicine, Tokyo, Japan. He also serves as the Director of the General Intensive Care Unit, Keio University Hospital.

Aims and scope

Journal of Intensive Care is an open access journal encompassing all aspects of intensive care medicine, such as intensive and critical care, trauma and surgical intensive care, pediatric intensive care, acute and emergency medicine, perioperative medicine, resuscitation, infection control and organ dysfunction. In addition, the journal encourages submissions considering the different cultural aspects of intensive care practice.

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