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  1. Disseminated intravascular coagulation (DIC) is a common complication in sepsis because of crosstalk between the immune system and the coagulation system. Several anticoagulant agents have been tested in an at...

    Authors: Yu Inata

    Citation: Journal of Intensive Care 2020 8:18

    Content type: Commentary

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  2. A high mortality rate is found among septic patients with disseminated intravascular coagulation (DIC). Anticoagulants have been used for treating septic DIC especially in Japanese clinical settings; however, ...

    Authors: Nobuyuki Yokoyama, Shunsuke Takaki, Masashi Yokose, Kaori Kuwabara, Akiko Anzai, Takako Hamada, Shizuka Kashiwagi, Kenta Okamura, Yoh Sugawara and Takahisa Goto

    Citation: Journal of Intensive Care 2020 8:17

    Content type: Commentary

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  3. Considering the adverse effects of sleep disturbance in critical care settings, accurate assessment could aid therapy; however, methodological inadequacies mean that no viable option is currently available. Re...

    Authors: Kanae Nagatomo, Tomoyuki Masuyama, Yusuke Iizuka, Jun Makino, Junji Shiotsuka and Masamitsu Sanui

    Citation: Journal of Intensive Care 2020 8:16

    Content type: Research

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  4. Treatment with intravenous paracetamol may impair hemodynamics in critically ill adults. Few data are available in children. The aim of this study was to investigate the frequency, extent, and risk factors of ...

    Authors: Elhanan Nahum, Avichai Weissbach, Eytan Kaplan and Gili Kadmon

    Citation: Journal of Intensive Care 2020 8:14

    Content type: Research

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  5. Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians. β-lactam antibiot...

    Authors: Teiji Sawa, Kunihiko Kooguchi and Kiyoshi Moriyama

    Citation: Journal of Intensive Care 2020 8:13

    Content type: Review

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  6. Neuromuscular blocking agent (NMBA) has been proposed by medical guidelines for early severe acute respiratory distress syndrome (ARDS) because of its survival benefits. However, new studies have provided evid...

    Authors: An Thi Nhat Ho, Setu Patolia and Christophe Guervilly

    Citation: Journal of Intensive Care 2020 8:12

    Content type: Research

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  7. Neutrophil gelatinase-associated lipocalin (NGAL) is a diagnostic marker for acute kidney injury (AKI). NGAL expression is highly induced not only in kidney injury but also in bacterial infection, inflammation...

    Authors: Chieko Mitaka, Chika Ishibashi, Izumi Kawagoe, Takashi Hashimoto, Makoto Takahashi, Daizoh Satoh and Eiichi Inada

    Citation: Journal of Intensive Care 2020 8:11

    Content type: Research

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  8. Clinically significant gastrointestinal bleeding from stress ulcers increases patient mortality in intensive care, and histamine type 2 receptor blockers and proton pump inhibitors as stress ulcer prophylaxes ...

    Authors: Osamu Ogasawara, Taiki Kojima, Mitsunori Miyazu and Kazuya Sobue

    Citation: Journal of Intensive Care 2020 8:10

    Content type: Research

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  9. In the original publication of this article [1], there were several transcription errors in the logistic regression equation model as below

    Authors: Raymond Kao, Fran Priestap and Allan Donner

    Citation: Journal of Intensive Care 2020 8:9

    Content type: Correction

    Published on:

    The original article was published in Journal of Intensive Care 2016 4:16

  10. Studies showed potential benefits of recombinant human-soluble thrombomodulin (rhTM) and antithrombin for treating sepsis associated disseminated intravascular coagulation. However, benefits of their combinati...

    Authors: Jun Suzuki, Yusuke Sasabuchi, Shuji Hatakeyama, Hiroki Matsui, Teppei Sasahara, Yuji Morisawa, Toshiyuki Yamada and Hideo Yasunaga

    Citation: Journal of Intensive Care 2020 8:8

    Content type: Research

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  11. Predisposing conditions and risk modifiers instead of causes and risk factors have recently been used as alternatives to identify patients at a risk of acute respiratory distress syndrome (ARDS). However, data...

    Authors: Hiroki Iriyama, Toshikazu Abe, Shigeki Kushimoto, Seitaro Fujishima, Hiroshi Ogura, Atsushi Shiraishi, Daizoh Saitoh, Toshihiko Mayumi, Toshio Naito, Akira Komori, Toru Hifumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Yasuhiro Otomo, Kohji Okamoto…

    Citation: Journal of Intensive Care 2020 8:7

    Content type: Research

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  12. Because critical illness survivors frequently experience several long-term psychological impairments altering quality of life after ICU, there is a trend towards increasing follow-up care, mainly via ICU follo...

    Authors: Johan H. Vlake, Michel E. van Genderen, Anna Schut, Martijn Verkade, Evert-Jan Wils, Diederik Gommers and Jasper van Bommel

    Citation: Journal of Intensive Care 2020 8:6

    Content type: Research

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  13. Sepsis is a global health priority. Interventions to reduce the burden of sepsis need to be both effective and cost-effective. We performed a systematic review of the literature on health economic evaluations ...

    Authors: Alisa M. Higgins, Joanne E. Brooker, Michael Mackie, D. Jamie Cooper and Anthony H. Harris

    Citation: Journal of Intensive Care 2020 8:5

    Content type: Research

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  14. Circadian clock alterations were poorly reported in trauma patients, although they have a critical role in human physiology. Core body temperature is a clinical variable regulated by the circadian clock. Our o...

    Authors: Aurélien Culver, Benjamin Coiffard, François Antonini, Gary Duclos, Emmanuelle Hammad, Coralie Vigne, Jean-Louis Mege, Karine Baumstarck, Mohamed Boucekine, Laurent Zieleskiewicz and Marc Leone

    Citation: Journal of Intensive Care 2020 8:4

    Content type: Research

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  15. Sepsis is the most common cause of premature death among patients with systemic lupus erythematosus (SLE) aged ≤ 50 years in the United States, and infection is the most common cause of admission to the ICU am...

    Authors: Lavi Oud

    Citation: Journal of Intensive Care 2020 8:3

    Content type: Research

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  16. In the original publication of this article [1], the first author’s name should be changed from Alexander Fletcher Sandersjöö to Alexander Fletcher-Sandersjöö. The family name of the author is Fletcher-Sanders...

    Authors: Alexander Fletcher-Sandersjöö, Jiri Bartek Jr, Eric Peter Thelin, Anders Eriksson, Adrian Elmi-Terander, Mikael Broman and Bo-Michael Bellander

    Citation: Journal of Intensive Care 2020 8:2

    Content type: Correction

    Published on:

    The original article was published in Journal of Intensive Care 2017 5:27

  17. Dexmedetomidine has been reported to improve organ dysfunction in critically ill patients. In a recent randomized controlled trial (Dexmedetomidine for Sepsis in Intensive Care Unit (ICU) Randomized Evolution ...

    Authors: Tsuyoshi Nakashima, Kyohei Miyamoto, Nozomu Shima, Seiya Kato, Yu Kawazoe, Yoshinori Ohta, Takeshi Morimoto and Hitoshi Yamamura

    Citation: Journal of Intensive Care 2020 8:1

    Content type: Research

    Published on:

  18. Recent studies have suggested that anticoagulant therapy does not confer a survival benefit overall in sepsis, but might be beneficial in sepsis-associated disseminated intravascular coagulation (DIC). In part...

    Authors: Takashi Ito, Takaaki Totoki, Yayoi Yokoyama, Tomotsugu Yasuda, Hiroaki Furubeppu, Shingo Yamada, Ikuro Maruyama and Yasuyuki Kakihana

    Citation: Journal of Intensive Care 2019 7:63

    Content type: Research

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  19. Non-convulsive status epilepticus (NCSE) is present in 10–30% of ICU patients with altered mental status (AMS) and is associated to poor outcomes. To our knowledge, there is no data describing the prevalence a...

    Authors: Cristina Gutierrez, Merry Chen, Lei Feng and Sudhakar Tummala

    Citation: Journal of Intensive Care 2019 7:62

    Content type: Research

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  20. Skeletal muscle atrophy commonly occurs in critically ill patients, and decreased muscle mass is associated with worse clinical outcomes. Muscle mass can be assessed using various tools, including ultrasound a...

    Authors: Nobuto Nakanishi, Rie Tsutsumi, Yoshihiro Okayama, Takuya Takashima, Yoshitoyo Ueno, Taiga Itagaki, Yasuo Tsutsumi, Hiroshi Sakaue and Jun Oto

    Citation: Journal of Intensive Care 2019 7:61

    Content type: Research

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  21. The aim of the study was to determine opinions and knowledge regarding the process of obtaining informed consent to participate in observational research in pediatric intensive care.

    Authors: Jessica Hodson, Christiana Garros, Jodie Jensen, Jonathan P. Duff, Gonzalo Garcia Guerra and Ari R. Joffe

    Citation: Journal of Intensive Care 2019 7:60

    Content type: Research

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  22. Critically ill traumatic brain injury (TBI) patients experience extensive muscle damage during their stay in the intensive care unit. Neuromuscular electrical stimulation (NMES) has been considered a promising...

    Authors: Paulo Eugênio Silva, Rita de Cássia Marqueti, Karina Livino-de-Carvalho, Amaro Eduardo Tavares de Araujo, Joana Castro, Vinicius Maldaner da Silva, Luciana Vieira, Vinicius Carolino Souza, Lucas Ogura Dantas, Gerson Cipriano Jr, Otávio Tolêdo Nóbrega, Nicolas Babault and Joao Luiz Quagliotti Durigan

    Citation: Journal of Intensive Care 2019 7:59

    Content type: Research

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  23. Serial lactate measurement is found to predict mortality in septic shock. Majority of patients with perforation peritonitis for emergency laparotomy are in sepsis and mortality rate is substantial. However, la...

    Authors: S. P. Jobin, Souvik Maitra, Dalim Kumar Baidya, Rajeshwari Subramaniam, Ganga Prasad and Vathulru Seenu

    Citation: Journal of Intensive Care 2019 7:58

    Content type: Research

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  24. This systematic review and meta-analysis of randomized clinical trials aimed to investigate the efficacy of early mobilization among critically ill adult patients.

    Authors: Yohei Okada, Takeshi Unoki, Yujiro Matsuishi, Yuko Egawa, Kei Hayashida and Shigeaki Inoue

    Citation: Journal of Intensive Care 2019 7:57

    Content type: Research

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  25. Diaphragm atrophy is observed in mechanically ventilated patients. However, the atrophy is not investigated in other respiratory muscles. Therefore, we conducted a two-center prospective observational study to...

    Authors: Nobuto Nakanishi, Jun Oto, Yoshitoyo Ueno, Emiko Nakataki, Taiga Itagaki and Masaji Nishimura

    Citation: Journal of Intensive Care 2019 7:56

    Content type: Research

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  26. The burden of sepsis is highest in low- and middle-income countries, though the management of sepsis in these settings is poorly characterized. Therefore, the objective of this study was to assess the early ma...

    Authors: Kristina E. Rudd, Viriya Hantrakun, Ranjani Somayaji, Suchart Booraphun, Chaiyaporn Boonsri, Annette L. Fitzpatrick, Nicholas P. J. Day, Prapit Teparrukkul, Direk Limmathurotsakul and T. Eoin West

    Citation: Journal of Intensive Care 2019 7:55

    Content type: Research

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  27. A spontaneous breathing trial (SBT) is a major diagnostic tool to predict successfully extubation in patients. Several factors may lead to weaning failure, including the degree of lung aeration loss and diaphr...

    Authors: Jing Xia, Chuan-Yun Qian, Li Yang, Mei-Ju Li, Xiao-Xue Liu, Ting Yang and Qin Lu

    Citation: Journal of Intensive Care 2019 7:54

    Content type: Research

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  28. Gait independence is one of the most important factors related to returning home from the hospital for patients treated in the intensive care unit (ICU), but the factors affecting gait independence have not be...

    Authors: Shinichi Watanabe, Toru Kotani, Shunsuke Taito, Kohei Ota, Kenzo Ishii, Mika Ono, Hajime Katsukawa, Ryo Kozu, Yasunari Morita, Ritsuro Arakawa and Shuichi Suzuki

    Citation: Journal of Intensive Care 2019 7:53

    Content type: Research

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  29. Traditional capillary refill time (CRT) is a manual measurement that is commonly used by clinicians to identify deterioration in peripheral perfusion status. Our study compared a novel method of measuring peri...

    Authors: Koichiro Shinozaki, Lee S. Jacobson, Kota Saeki, Hideaki Hirahara, Naoki Kobayashi, Steve Weisner, Julianne M. Falotico, Timmy Li, Junhwan Kim and Lance B. Becker

    Citation: Journal of Intensive Care 2019 7:52

    Content type: Research

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  30. The majority of patients with hemorrhagic stroke experience enhanced renal clearance or augmented renal clearance (ARC). The purpose of this study was to determine the impact of enhanced renal clearance or ARC...

    Authors: Kathryn A. Morbitzer, Denise H. Rhoney, Kelly A. Dehne and J. Dedrick Jordan

    Citation: Journal of Intensive Care 2019 7:51

    Content type: Research

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  31. Ventilator weaning protocols have been shown to reduce the duration of mechanical ventilation (MV), intensive care unit length of stay, and resource use. However, weaning protocols have not significantly affec...

    Authors: Kenichi Nitta, Kazufumi Okamoto, Hiroshi Imamura, Katsunori Mochizuki, Hiroshi Takayama, Hiroshi Kamijo, Mayumi Okada, Kanako Takeshige, Yuichiro Kashima and Takahisa Satou

    Citation: Journal of Intensive Care 2019 7:50

    Content type: Research

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  32. Alcohol withdrawal syndrome (AWS) is commonly treated in medical ICUs and typically requires high resource utilization. Dexmedetomidine for AWS has not been extensively investigated, and guidelines regarding i...

    Authors: Ekaterina R. Yavarovich, Maythawee Bintvihok, Justin C. McCarty, Janis L. Breeze and Peter LaCamera

    Citation: Journal of Intensive Care 2019 7:49

    Content type: Research

    Published on:

  33. Frailty status is recognized as an important parameter in critically ill elderly patients, but nothing is known about outcomes in non-frail patients regarding the development of frailty or frailty and death af...

    Authors: Yoann Launey, Hervé Jacquet, Matthieu Arnouat, Chloe Rousseau, Nicolas Nesseler and Philippe Seguin

    Citation: Journal of Intensive Care 2019 7:48

    Content type: Research

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  34. Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states. Medical literature has both explicitly stated and implied th...

    Authors: Roshan Bisarya, Deena Shaath, Arman Pirzad, Lewis Satterwhite, Jianghua He and Steven Q. Simpson

    Citation: Journal of Intensive Care 2019 7:47

    Content type: Research

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  35. Early recognition of sepsis is challenging, and diagnostic criteria have changed repeatedly. We assessed the robustness of sepsis-3 criteria in intensive care unit (ICU) patients.

    Authors: Diana M. Verboom, Jos F. Frencken, David S. Y. Ong, Janneke Horn, Tom van der Poll, Marc J. M. Bonten, Olaf L. Cremer and Peter M. C. Klein Klouwenberg

    Citation: Journal of Intensive Care 2019 7:46

    Content type: Research

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  36. Extracorporeal carbon dioxide removal (ECCO2R) is a promising technique for the management of acute respiratory failure, but with a limited level of evidence to support its use outside clinical trials and/or data...

    Authors: J. L. Augy, N. Aissaoui, C. Richard, E. Maury, M. Fartoukh, A. Mekontso-Dessap, R. Paulet, N. Anguel, C. Blayau, Y. Cohen, J. D. Chiche, S. Gaudry, S. Voicu, A. Demoule, A. Combes, B. Megarbane…

    Citation: Journal of Intensive Care 2019 7:45

    Content type: Research

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  37. We investigated if early intensive care unit (ICU) scoring with the Simplified Acute Physiology Score (SAPS 3) could be improved using artificial neural networks (ANNs).

    Authors: Gustav Holmgren, Peder Andersson, Andreas Jakobsson and Attila Frigyesi

    Citation: Journal of Intensive Care 2019 7:44

    Content type: Research

    Published on:

  38. An error occurred during the publication of a number of articles in Journal of Intensive Care. Several articles were published in volume 7 with a duplicate citation number.

    Authors:

    Citation: Journal of Intensive Care 2019 7:43

    Content type: Publisher Correction

    Published on:

    The original article was published in Journal of Intensive Care 2019 7:35

    The original article was published in Journal of Intensive Care 2019 7:34

  39. Fluid infusion represents one of the cornerstones of resuscitation therapies in order to increase oxygen delivery during septic shock. Fluid overload as a consequence of excessive fluid administration seems to...

    Authors: Xavier Chapalain, Véronique Vermeersch, Pierre-Yves Egreteau, Gwenael Prat, Zarrin Alavi, Eric Vicaut and Olivier Huet

    Citation: Journal of Intensive Care 2019 7:42

    Content type: Research

    Published on:

  40. With Sepsis-3, the increase in sequential organ failure assessment (SOFA) as a clinical score for the identification of patients with sepsis and quickSOFA (qSOFA) for the identification of patients at risk of ...

    Authors: Lucie Probst, Enrico Schalk, Tobias Liebregts, Vanja Zeremski, Asterios Tzalavras, Michael von Bergwelt-Baildon, Nina Hesse, Johanna Prinz, Jörg Janne Vehreschild, Alexander Shimabukuro-Vornhagen, Dennis A. Eichenauer, Jorge Garcia Borrega, Matthias Kochanek and Boris Böll

    Citation: Journal of Intensive Care 2019 7:41

    Content type: Research

    Published on:

  41. In the original publication of this article [1], the content of Authors’ contributions needs to be revised as below:

    Authors: Hendrik Gussen, Philipp Hohlstein, Matthias Bartneck, Klaudia Theresa Warzecha, Lukas Buendgens, Tom Luedde, Christian Trautwein, Alexander Koch and Frank Tacke

    Citation: Journal of Intensive Care 2019 7:40

    Content type: Correction

    Published on:

    The original article was published in Journal of Intensive Care 2019 7:26

  42. Commencement of a new academic cycle is presumed to be associated with poor patient outcomes. However, supportive evidence is limited for trauma patients treated in under-resourced hospitals, especially those ...

    Authors: Yuko Ono, Takeyasu Kakamu, Tokiya Ishida, Tetsu Sasaki, Shigeaki Inoue, Joji Kotani and Kazuaki Shinohara

    Citation: Journal of Intensive Care 2019 7:39

    Content type: Research

    Published on:

  43. The length of stay (LOS) in intensive care units (ICUs) has been used as a good indicator not only for resource consumption but also for health outcomes of patients. However, data regarding pediatric LOS in Ja...

    Authors: Emily Knaup, Nobuyuki Nosaka, Takashi Yorifuji, Kohei Tsukahara, Hiromichi Naito, Hirokazu Tsukahara and Atsunori Nakao

    Citation: Journal of Intensive Care 2019 7:38

    Content type: Research

    Published on:

  44. Appropriate use of antimicrobials is essential to improve outcomes in sepsis. The aim of this study was to determine whether the use of a rapid molecular blood test—SeptiFast (SF) reduces the antibiotic consumpti...

    Authors: Cristhieni Rodrigues, Rinaldo Focaccia Siciliano, Helio Caiaffa Filho, Cecília Eugenia Charbel, Luciane de Carvalho Sarahyba da Silva, Martina Baiardo Redaelli, Ana Paula de Paula Rosa Passetti, Maria Renata Gomes Franco, Flávia Rossi, Rogerio Zeigler, Daniel De Backer, Rafael Alves Franco, Juliano Pinheiro de Almeida, Stéphanie Itala Rizk, Julia Tizue Fukushima, Giovanni Landoni…

    Citation: Journal of Intensive Care 2019 7:37

    Content type: Research

    Published on:

  45. The objective of this study was to determine the main risk factors of Pseudomonas aeruginosa mutation as well as the mechanisms of acquired resistance.

    Authors: Stéphanie Druge, Stéphanie Ruiz, Fanny Vardon-Bounes, Marion Grare, François Labaste, Thierry Seguin, Olivier Fourcade, Vincent Minville, Jean-Marie Conil and Bernard Georges

    Citation: Journal of Intensive Care 2019 7:36

    Content type: Research

    Published on:

  46. We examined whether high lactate level in septic patients was associated with 90-day mortality based on the patients’ disseminated intravascular coagulation (DIC) status.

    Authors: Daisuke Hasegawa, Kazuki Nishida, Yoshitaka Hara, Takahiro Kawaji, Kazuhiro Moriyama, Yasuyo Shimomura, Daisuke Niimi, Hidefumi Komura and Osamu Nishida

    Citation: Journal of Intensive Care 2019 7:35

    Content type: Research

    Published on:

    The Publisher Correction to this article has been published in Journal of Intensive Care 2019 7:43

  47. In the original publication of this article [1], the figure legends of Fig. 2 and Fig. 3 are wrong and should be changed as below:

    Authors: Yohei Okada, Tasuku Matsuyama, Sachiko Morita, Naoki Ehara, Nobuhiro Miyamae, Takaaki Jo, Yasuyuki Sumida, Nobunaga Okada, Makoto Watanabe, Masahiro Nozawa, Ayumu Tsuruoka, Yoshihiro Fujimoto, Yoshiki Okumura, Tetsuhisa Kitamura, Shungo Yamamoto, Ryoji Iiduka…

    Citation: Journal of Intensive Care 2019 7:34

    Content type: Correction

    Published on:

    The Publisher Correction to this article has been published in Journal of Intensive Care 2019 7:43

    The original article was published in Journal of Intensive Care 2019 7:27

  48. Disseminated intravascular coagulation (DIC) is a common complication in sepsis. Since DIC not only promotes organ dysfunction but also is a strong prognostic factor, its diagnosis at the earliest possible tim...

    Authors: Toshiaki Iba, Eizo Watanabe, Yutaka Umemura, Takeshi Wada, Kei Hayashida, Shigeki Kushimoto and Hideo Wada

    Citation: Journal of Intensive Care 2019 7:32

    Content type: Review

    Published on: