Candida spp. infections are a major cause of morbidity and mortality in critically ill patients. Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading worldwide. Since the first repor...
Authors: Andrea Cortegiani, Giovanni Misseri, Teresa Fasciana, Anna Giammanco, Antonino Giarratano and Anuradha Chowdhary
The advances of research on extracellular vesicles (EVs) are of particular interest to the clinicians as well as the researchers who are studying coagulation disorder in sepsis. Here, we intend to update the l...
Patients who require a prolonged weaning process comprise a highly heterogeneous group of patients amongst whom the outcome differs significantly. The present study aimed to identify the factors that predict w...
Authors: Friederike Sophie Magnet, Hannah Bleichroth, Sophie Emilia Huttmann, Jens Callegari, Sarah Bettina Schwarz, Claudia Schmoor, Wolfram Windisch and Jan Hendrik Storre
Pneumonia complicated by septic shock is associated with significant morbidity and mortality. Classification and regression tree methodology is an intuitive method for predicting clinical outcomes using binary...
Authors: Jaime L Speiser, Constantine J Karvellas, Geoffery Shumilak, Wendy I Sligl, Yazdan Mirzanejad, Dave Gurka, Aseem Kumar and Anand Kumar
Several advanced and developing countries are now entering a superaged society, in which the percentage of elderly people exceeds 20% of the total population. In such an aging society, the number of age-relate...
Authors: Shigeaki Inoue, Masafumi Saito and Joji Kotani
Management of patients with acute respiratory distress syndrome (ARDS) remains supportive with lung protective mechanical ventilation. In this article, we discuss the physiological concept of driving pressure,...
Authors: Hiroko Aoyama, Yoshitsugu Yamada and Eddy Fan
Community-acquired gram-negative bacillary meningitis is rare to occur without preexisting conditions like trauma, organ dysfunction, and immunocompromised state, and very few case reports with Escherichia coli h...
Authors: Rajesh Kasimahanti, Sai Kandraju Satish and Mridu Anand
Analgosedation is a cornerstone therapy for mechanically ventilated patients in intensive care units (ICU). To avoid inadequate sedation and its complications, monitoring of analgosedation is of great importan...
Authors: Richard J. Nies, Carsten Müller, Roman Pfister, Philipp S. Binder, Nicole Nosseir, Felix S. Nettersheim, Kathrin Kuhr, Martin H. J. Wiesen, Matthias Kochanek and Guido Michels
Cefepime can be removed by continuous renal replacement therapy (CRRT) due to its pharmacokinetics. The purpose of this study is to define the optimal cefepime dosing regimens for critically ill patients recei...
Both anaemia and red blood cell (RBC) transfusion are common and associated with adverse outcomes in patients admitted to the intensive care unit (ICU). The aim of this study was to determine whether serum hep...
Authors: Edward Litton, Stuart Baker, Wendy Erber, Shannon Farmer, Janet Ferrier, Craig French, Joel Gummer, David Hawkins, Alisa Higgins, Axel Hofmann, Bart De Keulenaer, Julie McMorrow, John K. Olynyk, Toby Richards, Simon Towler, Robert Trengove…
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly used in the treatment of depression. While most intoxications with SSRI’s have favorable outcomes and do not require interventions other t...
Authors: Jan Albert Nicolaas Groot, Leonore ten Bokum and Hubertus Laurentius Antonius van den Oever
Recent, large trials of high-frequency oscillation (HFO) versus conventional ventilation (CV) in acute respiratory distress syndrome (ARDS) reported negative results. This could be explained by an HFO-induced ...
Authors: Spyros D. Mentzelopoulos, Hector Anninos, Sotirios Malachias and Spyros G. Zakynthinos
We aimed to determine predictors of, and outcomes after, veno-arterial extracorporeal membrane oxygenation instituted within 48 h after cardiac surgery (early ECMO) in young infants.
Authors: Gabriela A. Kuraim, Daniel Garros, Lindsay Ryerson, Fahimeh Moradi, Irina A. Dinu, Gonzalo Garcia Guerra, Diane Moddemann, Gwen Y. Bond, Charlene M. T. Robertson and Ari R. Joffe
Intravenous glycerol treatment, usually administered in the form of a 5% fructose solution, can be used to reduce intracranial pressure. The administered fructose theoretically influences blood lactate levels,...
Authors: Shinshu Katayama, Ken Tonai, Yuya Goto, Kansuke Koyama, Toshitaka Koinuma, Jun Shima, Masahiko Wada and Shin Nunomiya
Although chest compression is a standard technique in cardiopulmonary resuscitation, it is well recognized that manual chest compression causes various internal injuries, of which major injuries are often fata...
Authors: Shigeaki Aoyagi, Tomokazu Kosuga, Kumiko Wada, Shin-ichi Nata and Hiroshi Yasunaga
Fluid responsiveness prediction with continuously available monitoring is an unsettled matter for the vast majority of critically ill patients, and development of new and reliable methods is desired. We hypoth...
Authors: Simon Tilma Vistisen, Martin Buhl Krog, Thomas Elkmann, Mikael Fink Vallentin, Thomas W. L. Scheeren and Christoffer Sølling
Intravenous fluids are one of the most used medical therapy for patients, especially critically ill patients. We conducted a meta-analysis comparing between balanced crystalloids and normal saline in criticall...
Authors: Yazan Z. M. Zayed, Ahmed M. Y. Aburahma, Mahmoud O. Barbarawi, Kewan Hamid, Momen R. N. Banifadel, Laith Rashdan and Ghassan I. Bachuwa
Echocardiography is often used to guide septic shock resuscitation, but without evidence for efficacy. We conducted an intensive care unit (ICU)-based randomized controlled feasibility trial comparing echocard...
Authors: Michael J. Lanspa, Rebecca E. Burk, Emily L. Wilson, Eliotte L. Hirshberg, Colin K. Grissom and Samuel M. Brown
Endotracheal intubation in critically ill is a high-risk procedure requiring significant expertise in airway handling as well as understanding of pathophysiology of the disease process.
Acute kidney injury (AKI) is a syndrome which has a broad range of etiologic factors depending on different clinical settings. Because AKI has significant impacts on prognosis in any clinical settings, early d...
The main problem of hospitalized patients in intensive care units is feeding, and if the patient does not receive the daily caloric intake required to his body, he will have malnutrition and problems related t...
Authors: Farzad Momenfar, Alireza Abdi, Nader Salari, Ali Soroush and Behzad Hemmatpour
Quick Sepsis-related Organ Failure Assessment (qSOFA) is a new screening system for sepsis. The prognostic performance of qSOFA for patients with suspected infections outside the intensive care unit (ICU) is s...
Because of the complex pathophysiological processes involved, neurocritical care has been driven by anecdotal experience and physician preferences, which has led to care variation worldwide. Standardization of...
Authors: Yasuhiro Norisue, Yoshihisa Fujimoto and Kazuma Nakagawa
Extubation failure is associated with mortality and morbidity in the intensive care unit. Ventilator weaning protocols have been introduced, and extubation is conducted based on the results of a spontaneous br...
New-onset refractory status epilepticus (NORSE) is a newly defined critical disease entity characterized by prolonged periods of refractory epileptic seizure with no readily identifiable cause in otherwise hea...
Reverse triggering is respiratory entrainment triggered by the ventilator especially seen among heavily sedated patients. We confirmed reverse triggering induced by auto-triggering in lightly sedated patient t...
Authors: Taiga Itagaki, Yoshitoyo Ueno, Nobuto Nakanishi and Jun Oto
Every day in the ICU, legal issues arise while treating sedated, unconscious, and legally incapacitated patients. Whenever a life-saving treatment cannot be discussed in a timely manner with an unconscious pat...
Authors: Doreen Stark, Ruth Stiller, Min Xie, Damian Weber, Marco Maggiorini and Matthias Peter Hilty
Continuous electroencephalogram (CEEG) monitoring is increasingly being used for brain monitoring in neurocritical care setting. This is because of the proven effectiveness of CEEG in diagnosing nonconvulsive ...
Authors: Yuichi Kubota, Hidetoshi Nakamoto, Satoshi Egawa and Takakazu Kawamata
Since the 2009 pandemic influenza, we have nationally established a committee of the extracorporeal membrane oxygenation (ECMO) project. This project involves adequate respiratory management for severe respira...
C1 inhibitor (C1-INH), which belongs to the superfamily of serine protease inhibitors, regulates the complement system and also the plasma kallikrein-kinin, fibrinolytic, and coagulation systems. The biologic ...
Authors: Tomoya Hirose, Hiroshi Ogura, Hiroki Takahashi, Masahiro Ojima, Kang Jinkoo, Youhei Nakamura, Takashi Kojima and Takeshi Shimazu
While outcome improvement with extracorporeal CO2 removal (ECCO2R) is not demonstrated, a strong pathophysiological rational supports its use in the setting of acute respiratory distress syndrome (ARDS) and COPD ...
Authors: Hadrien Winiszewski, François Aptel, François Belon, Nicolas Belin, Claire Chaignat, Cyrille Patry, Cecilia Clermont, Elise David, Jean-Christophe Navellou, Guylaine Labro, Gaël Piton and Gilles Capellier
Clinical benefits of recruitment maneuver in ARDS patients are controversial. A number of previous studies showed possible benefits; a large recent study reported that recruitment maneuver and PEEP titration m...
Authors: Sulagna Bhattacharjee, Kapil D. Soni and Souvik Maitra
Although factor Xa inhibitors have become a popular choice for chronic oral anticoagulation, effective drug reversal remains difficult due to a lack of specific antidote. Currently, 4-factor prothrombin comple...
Authors: Jing Tao, Elena N. Bukanova and Shamsuddin Akhtar
Serum lactate level can predict clinical outcomes in some critical cases. In the clinical setting, we noted that patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) and with poor serum lact...
The author noted that major part of Acknowledgements section was inadvertently missing in the original article [1]. The new Acknowledgements can be found below.
Authors: Yoshinori Kobayashi
Citation:Journal of Intensive Care
2018
6:31
Published on: 24 May 2018
The
original article was published in Journal of Intensive Care
2018
6:23
Heat stroke is a life-threatening injury requiring neurocritical care; however, heat stroke has not been completely examined due to several possible reasons, such as no universally accepted definition or class...
Authors: Toru Hifumi, Yutaka Kondo, Keiki Shimizu and Yasufumi Miyake
The case reinforces the importance of stepping back and looking at every possibility along with multiple co-existing pathologies. It takes into account the thought process of multiple systems and a multidiscip...
Aneurysmal subarachnoid hemorrhage is a life-threatening disease requiring neurocritical care. Delayed cerebral ischemia is a well-known complication that contributes to unfavorable neurological outcomes. Cere...
Protracted treatment on intensive care unit (ICU) sets the patients at increased risk for the development of chronic critical illness (CCI). Muscular and cardio-respiratory deconditioning are common long-term ...
Authors: Gloria-Beatrice Wintermann, Jenny Rosendahl, Kerstin Weidner, Bernhard Strauß, Andreas Hinz and Katja Petrowski
Early brain CT is one of the most useful tools for estimating the prognosis in patients with post-cardiac arrest syndrome (PCAS) at the emergency department (ED). The aim of this study was to evaluate the prog...
To determine the frequency of limitations on life support techniques (LLSTs) on admission to intensive care units (ICU), factors associated, and 30-day survival in patients with LLST on ICU admission.
Authors: Olga Rubio, Anna Arnau, Sílvia Cano, Carles Subirà, Begoña Balerdi, María Eugenía Perea, Miguel Fernández-Vivas, María Barber, Noemí Llamas, Susana Altaba, Ana Prieto, Vicente Gómez, Mar Martin, Marta Paz, Belen Quesada, Valentí Español…
In the clinical practice of cardiovascular critical care, we often observe a variety of arrhythmias in the patients either with (secondary) or without (idiopathic) underlying heart diseases. In this manuscript...
ILT4+ monocytes seem to be associated with poor prognosis of sepsis in humans, but the exact mechanisms are unknown. This study aimed to examine the biological behaviors and effects of immunoglobulin-like transcr...
Magnesium (Mg) is essential for life and plays a crucial role in several biochemical and physiological processes in the human body. Hypomagnesemia is common in all hospitalized patients, especially in critical...
Multi-organ failure occurs during critical illness and is mediated in part by destructive neutrophil-to-endothelial interactions. The β2 integrin receptor, CR3 (complement receptor 3; Mac-1; CD11b/CD18), which...
Authors: Catherine M. Dickinson, Brian W. LeBlanc, Muhammad M. Edhi, Daithi S. Heffernan, Mohd. Hafeez Faridi, Vineet Gupta, William G. Cioffi, Xian O’Brien and Jonathan S. Reichner
