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  1. Previous studies show positive effect of music on reducing anxiety, pain, and medication requirement. Anxiety has become a more pertinent issue in the intensive care unit (ICU) since wakefulness is preferred a...

    Authors: Ellaha Kakar, Thomas Ottens, Susanne Stads, Sanne Wesselius, Diederik A. M. P. J. Gommers, Johannes Jeekel and Mathieu van der Jagt
    Citation: Journal of Intensive Care 2023 11:36
  2. Despite the understanding of sepsis-induced extracellular vesicles (EVs), such as exosomes, and their role in intercellular communication during sepsis, little is known about EV contents such as microRNA (miRN...

    Authors: Beomsu Shin, Jin Young Lee, Yunjoo Im, Hongseok Yoo, Junseon Park, Joo Sang Lee, Ki-Young Lee and Kyeongman Jeon
    Citation: Journal of Intensive Care 2023 11:35
  3. The efficacies of fresh frozen plasma and coagulation factor transfusion have been widely evaluated in trauma-induced coagulopathy management during the acute post-injury phase. However, the efficacy of red bl...

    Authors: Mineji Hayakawa, Takashi Tagami, Daisuke Kudo, Kota Ono, Makoto Aoki, Akira Endo, Tetsuya Yumoto, Yosuke Matsumura, Shiho Irino, Kazuhiko Sekine, Noritaka Ushio, Takayuki Ogura, Sho Nachi, Yuhei Irie, Katsura Hayakawa, Yusuke Ito…
    Citation: Journal of Intensive Care 2023 11:34
  4. Mechanisms underpinning ARDS induced by COVID-19 are mostly immune-mediated, but need to be completely clarified. This study aimed to investigate redox balance in COVID-19 patients with ARDS, trying to recogni...

    Authors: Francesco Bellanti, Sławomir Kasperczyk, Aleksandra Kasperczyk, Michał Dobrakowski, Gabriella Pacilli, Giuseppina Vurchio, Alessandro Maddalena, Stefano Quiete, Aurelio Lo Buglio, Cristiano Capurso, Gaetano Serviddio and Gianluigi Vendemiale
    Citation: Journal of Intensive Care 2023 11:30
  5. A unified clinical definition of feeding intolerance (FI) is urged for better management of enteral nutrition (EN) in critically ill patients. We aimed to identify optimum clinical FI definitions based on repo...

    Authors: Jianbo Li, Lijie Wang, Huan Zhang, Tongjuan Zou, Yan Kang, Wei He, Yuan Xu and Wanhong Yin
    Citation: Journal of Intensive Care 2023 11:29
  6. Tissue Doppler-derived left ventricular systolic velocity (mitral S’) has shown excellent correlation to left ventricular ejection fraction (LVEF) in non-critically patients. However, their correlation in sept...

    Authors: Sanchit Chawla, Ryota Sato, Abhijit Duggal, Mahmoud Alwakeel, Daisuke Hasegawa, Dina Alayan, Patrick Collier, Filippo Sanfilippo, Michael Lanspa and Siddharth Dugar
    Citation: Journal of Intensive Care 2023 11:28
  7. The effects of body mass index (BMI) on mortality of sepsis remain unknown, since previous meta-analyses have reported conflicting results. Several observational studies published recently have provided new ev...

    Authors: Le Bai, Jingyi Huang, Dan Wang, Dongwei Zhu, Qi Zhao, Tingyuan Li, Xianmei Zhou and Yong Xu
    Citation: Journal of Intensive Care 2023 11:27
  8. Cardiogenic shock (CS) is caused by primary cardiac dysfunction and induced by various and heterogeneous diseases (e.g., acute impairment of cardiac performance, or acute or chronic impairment of cardiac perfo...

    Authors: Akihiro Shirakabe, Masato Matsushita, Yusaku Shibata, Shota Shighihara, Suguru Nishigoori, Tomofumi Sawatani, Kazutaka Kiuchi and Kuniya Asai
    Citation: Journal of Intensive Care 2023 11:26
  9. Post-pyloric enteral feeding reduces respiratory complications and shortens the duration of mechanical ventilation. Blind placement of post-pyloric enteral feeding tubes (EFT) in patients with critical illness...

    Authors: Masashi Yokose, Shunsuke Takaki, Yusuke Saigusa, Takahiro Mihara, Yoshinobu Ishiwata, Shingo Kato, Keiichi Horie and Takahisa Goto
    Citation: Journal of Intensive Care 2023 11:25
  10. The International Society on Thrombosis and Haemostasis (ISTH) released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001. Since then, DIC has been understood as the end-stage cons...

    Authors: Toshiaki Iba, Julie Helms, Jean Marie Connors and Jerrold H. Levy
    Citation: Journal of Intensive Care 2023 11:24
  11. An increasing number of patients are surviving critical illness, but some experience new or worsening long-lasting impairments in physical, cognitive and/or mental health, commonly known as post-intensive care...

    Authors: Stephanie L. Hiser, Arooj Fatima, Mazin Ali and Dale M. Needham
    Citation: Journal of Intensive Care 2023 11:23
  12. Transpulmonary pressure is an essential physiologic concept as it reflects the true pressure across the alveoli, and is a more precise marker for lung stress. To calculate transpulmonary pressure, one needs an...

    Authors: Tatsutoshi Shimatani, Miyako Kyogoku, Yukie Ito, Muneyuki Takeuchi and Robinder G. Khemani
    Citation: Journal of Intensive Care 2023 11:22
  13. Long-term outcomes of patients treated with helmet noninvasive ventilation (NIV) are unknown: safety concerns regarding the risk of patient self-inflicted lung injury and delayed intubation exist when NIV is a...

    Authors: Teresa Michi, Chiara Mattana, Luca S. Menga, Maria Grazia Bocci, Melania Cesarano, Tommaso Rosà, Maria Rosaria Gualano, Jonathan Montomoli, Savino Spadaro, Matteo Tosato, Elisabetta Rota, Francesco Landi, Salvatore L. Cutuli, Eloisa S. Tanzarella, Gabriele Pintaudi, Edoardo Piervincenzi…
    Citation: Journal of Intensive Care 2023 11:21
  14. Postoperative delirium in intensive care is common and associated with mortality, cognitive impairment, prolonged hospital stays and high costs. We evaluate whether a nurse-led orientation program could reduce...

    Authors: Ryo Nakamura, Kyohei Miyamoto, Kaori Tsuji, Kana Ozaki, Hideki Kunimoto, Kentaro Honda, Yoshiharu Nishimura and Seiya Kato
    Citation: Journal of Intensive Care 2023 11:20
  15. High-flow nasal cannula (HFNC) has been proven effective in improving patients with acute hypoxemic respiratory failure (AHRF), but a discussion of its use for initial flow settings still need to be provided. ...

    Authors: Yuewen He, Xuhui Zhuang, Hao Liu and Wuhua Ma
    Citation: Journal of Intensive Care 2023 11:18
  16. Increased estimated whole blood viscosity (eWBV) predicts higher mortality in patients hospitalized for coronavirus disease 2019 (COVID-19). This study assesses whether eWBV is an early predictor of non-fatal ...

    Authors: Ori Waksman, Daein Choi, Phyu Mar, Qinzhong Chen, Daniel J. Cho, HyoungSup Kim, Robin L. Smith, Sascha N. Goonewardena and Robert S. Rosenson
    Citation: Journal of Intensive Care 2023 11:17
  17. Based on sparse evidence, the current Surviving Sepsis Campaign guideline suggests that critically ill patients with sepsis be admitted to the intensive care unit (ICU) within 6 h. However, limited ICU bed ava...

    Authors: Yoon Hae Ahn, Jinwoo Lee, Dong Kyu Oh, Su Yeon Lee, Mi Hyeon Park, Haein Lee, Chae-Man Lim, Sang-Min Lee and Hong Yeul Lee
    Citation: Journal of Intensive Care 2023 11:16
  18. Hemolysis is associated with increased mortality in patients with sepsis, ARDS, or therapy with extracorporeal membrane oxygenation (ECMO). To quantify a critical threshold of hemolysis in patients with ARDS a...

    Authors: Victoria Bünger, Oliver Hunsicker, Alexander Krannich, Felix Balzer, Claudia D. Spies, Wolfgang M. Kuebler, Steffen Weber-Carstens, Mario Menk and Jan A. Graw
    Citation: Journal of Intensive Care 2023 11:15
  19. Previous studies linked a high intensity of ventilation, measured as mechanical power, to mortality in patients suffering from “classic” ARDS. By contrast, mechanically ventilated patients with a diagnosis of ...

    Authors: Basit A. Azizi, Ricardo Munoz-Acuna, Aiman Suleiman, Elena Ahrens, Simone Redaelli, Tim M. Tartler, Guanqing Chen, Boris Jung, Daniel Talmor, Elias N. Baedorf-Kassis and Maximilian S. Schaefer
    Citation: Journal of Intensive Care 2023 11:14
  20. Augmented renal clearance (ARC) is associated with lower blood plasma concentrations of renally excreted drugs; however, its time course is unknown. The current study aimed to determine the onset timing/durati...

    Authors: Ryusei Mikami, Mineji Hayakawa, Shungo Imai, Mitsuru Sugawara and Yoh Takekuma
    Citation: Journal of Intensive Care 2023 11:13
  21. The public enquiry into the mass casualty incident at the Manchester Arena in the UK in which 23 people died and over 1000 were injured, identified the need for timely intramuscular administration of tranexami...

    Authors: Kazuhiko Omori and Ian Roberts
    Citation: Journal of Intensive Care 2023 11:12
  22. Acute kidney injury (AKI) is a frequent syndrome in the intensive care unit (ICU). AKI patients with kidney function recovery have better short-term and long-term prognoses compared with those with non-recover...

    Authors: Ben-Shu Qian, Hui-Miao Jia, Yi-Bing Weng, Xin-Cheng Li, Chao-Dong Chen, Fang-Xing Guo, Yu-Zhen Han, Li-Feng Huang, Yue Zheng and Wen-Xiong Li
    Citation: Journal of Intensive Care 2023 11:11
  23. The telemedicine intensive care unit (Tele-ICU) is defined as a system in which intensive care professionals remotely provide care to critically ill patients and support the on-site staff in the intensive care...

    Authors: Taro Watanabe, Koichi Ohsugi, Yuri Suminaga, Masayuki Somei, Kazuki Kikuyama, Maiko Mori, Hiroko Maruo, Nao Kono and Toru Kotani
    Citation: Journal of Intensive Care 2023 11:9
  24. The development of disseminated intravascular coagulation (DIC) in patients with sepsis has been repeatedly confirmed as a factor associated with poor prognosis. Anticoagulant therapy has been expected to impr...

    Authors: Takeshi Wada, Kazuma Yamakawa, Daijiro Kabata, Toshikazu Abe, Seitaro Fujishima, Shigeki Kushimoto, Toshihiko Mayumi, Hiroshi Ogura, Daizoh Saitoh, Atsushi Shiraishi, Yasuhiro Otomo and Satoshi Gando
    Citation: Journal of Intensive Care 2023 11:8
  25. Little data exist on the time spent by emergency department (ED) personnel providing intravenous (IV) fluid to ‘responsive’ versus ‘unresponsive’ patients.

    Authors: Jon-Émile S. Kenny, Stanley O. Gibbs, Delaney Johnston, Zhen Yang, Lisa M. Hofer, Mai Elfarnawany, Joseph K. Eibl, Amanda Johnson, Anthony J. Buecker, Vivian C. Lau and Benjamin O. Kemp
    Citation: Journal of Intensive Care 2023 11:7
  26. Children with community-acquired septic shock can rapidly deteriorate and die in acute-care hospitals. This study aimed to describe the mortality, timing, and risk factors in children with community-acquired s...

    Authors: Shinya Miura, Nobuaki Michihata, Yohei Hashimoto, Hiroki Matsui, Kiyohide Fushimi and Hideo Yasunaga
    Citation: Journal of Intensive Care 2023 11:6
  27. A growing body of evidence supports the use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) refractory to maximal medical therapy. ARDS may develop in a prop...

    Authors: Francesco Alessandri, Matteo Di Nardo, Kollengode Ramanathan, Daniel Brodie and Graeme MacLaren
    Citation: Journal of Intensive Care 2023 11:5
  28. Current guidelines recommend systemic thrombolysis as the first-line reperfusion treatment for patients with high-risk pulmonary embolism (PE) who present with cardiogenic shock but do not require venoarterial...

    Authors: Yuji Nishimoto, Hiroyuki Ohbe, Hiroki Matsui, Mikio Nakajima, Yusuke Sasabuchi, Yukihito Sato, Tetsuya Watanabe, Takahisa Yamada, Masatake Fukunami and Hideo Yasunaga
    Citation: Journal of Intensive Care 2023 11:4
  29. sCD59, as a soluble form of CD59, is observed in multiple types of body fluids and correlated with the cell damage after ischemia/reperfusion injury. This study aims to observe the dynamic changes of serum sCD...

    Authors: Ling Wang, Rui-Fang Li, Xiao-Lan Guan, Shuang-Shuang Liang and Ping Gong
    Citation: Journal of Intensive Care 2023 11:3
  30. A substantial number of sepsis patients require specialized care, including multidisciplinary care, close monitoring, and artificial organ support in the intensive care unit (ICU). However, the efficacy of ICU...

    Authors: Takehiko Oami, Taro Imaeda, Taka‑aki Nakada, Toshikazu Abe, Nozomi Takahashi, Yasuo Yamao, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima and Kiyohide Fushimi
    Citation: Journal of Intensive Care 2023 11:2
  31. Tigecycline has in vitro bacteriostatic activity against a broad spectrum of bacteria, including carbapenem-resistant Gram-negative bacteria (CR-GNB). However, the role of tigecycline in treatment of nosocomia...

    Authors: Kuang-Yao Yang, Chung-Kan Peng, Chau-Chyun Sheu, Yu-Chao Lin, Ming-Cheng Chan, Sheng-Huei Wang, Chia-Min Chen, Chih-Yu Chen, Zhe-Rong Zheng and Jia-Yih Feng
    Citation: Journal of Intensive Care 2023 11:1
  32. Extracorporeal membrane oxygenation (ECMO) is an integral method of life support in critically ill patients with severe cardiopulmonary failure; however, such patients generally require prolonged mechanical ve...

    Authors: Ryota Nukiwa, Akinori Uchiyama, Aiko Tanaka, Tetsuhisa Kitamura, Ryota Sakaguchi, Yoshimitsu Shimomura, Suguru Ishigaki, Yusuke Enokidani, Tomonori Yamashita, Yukiko Koyama, Takeshi Yoshida, Natsuko Tokuhira, Naoya Iguchi, Yasushi Shintani, Shigeru Miyagawa and Yuji Fujino
    Citation: Journal of Intensive Care 2022 10:56
  33. Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory set...

    Authors: Laura Amado-Rodríguez, Raquel Rodríguez-Garcia, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, John G. Laffey and Guillermo M. Albaiceta
    Citation: Journal of Intensive Care 2022 10:55
  34. The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. The objective was to determine how delirium subtypes are associated with hospital morta...

    Authors: Lisa Smit, Eveline J. A. Wiegers, Zoran Trogrlic, Wim J. R. Rietdijk, Diederik Gommers, Erwin Ista and Mathieu van der Jagt
    Citation: Journal of Intensive Care 2022 10:54
  35. The coronavirus disease 2019 (COVID-19) pandemic has disrupted critical care services worldwide. Examining how critical care systems responded to the COVID-19 pandemic on a national level will be useful in set...

    Authors: Hiroyuki Ohbe, Yusuke Sasabuchi, Hiroki Matsui and Hideo Yasunaga
    Citation: Journal of Intensive Care 2022 10:51
  36. Given the available clinical evidence through the literature search when the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 was being created, we suggested administering v...

    Authors:
    Citation: Journal of Intensive Care 2022 10:50
  37. The appropriate duration of antibiotic treatment in patients with bacterial sepsis remains unclear. The purpose of this study was to evaluate the association of a shorter course of antibiotics on 28-day mortal...

    Authors: Nozomi Takahashi, Taro Imaeda, Taka‑aki Nakada, Takehiko Oami, Toshikazu Abe, Yasuo Yamao, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Asako Matsushima and Kiyohide Fushimi
    Citation: Journal of Intensive Care 2022 10:49
  38. Fontan surgery with cardiopulmonary bypass (CPB) causes tremendous systemic stress and inflammatory responses, affecting postoperative organ function, morbidity, and mortality. Although this reaction triggers ...

    Authors: Jacek Kolcz, Elzbieta Karnas, Zbigniew Madeja and Ewa K. Zuba-Surma
    Citation: Journal of Intensive Care 2022 10:48
  39. Acute respiratory distress syndrome (ARDS), a prevalent cause of admittance to intensive care units, is associated with high mortality. Prone positioning has been proven to improve the outcomes of moderate to ...

    Authors: Hongling Zhang, Zhengdong Liu, Huaqing Shu, Yuan Yu, Xiaobo Yang, Ruiting Li, Jiqian Xu, Xiaojing Zou and You Shang
    Citation: Journal of Intensive Care 2022 10:46
  40. There is little known about the contribution of microRNAs (miRNAs) in the recovery from acute kidney injury (AKI). This study aimed to discover and validate miRNA profiles for predicting renal recovery from se...

    Authors: Thanawat Phulkerd, Tanat Lertussavavivat, Umaporn Limothai, Sadudee Peerapornratana, Win Kulvichit, Nuttha Lumlertgul, Kriang Tungsanga, Somchai Eiam-Ong, Yingyos Avihingsanon and Nattachai Srisawat
    Citation: Journal of Intensive Care 2022 10:45
  41. Up to 11% of critically ill patients with sepsis have an unknown source, where the pathogen and site of infection are unclear. The aim of this scoping review is to document currently reported diagnostic criter...

    Authors: Lowell Ling, Oliver Oi Yat Mui, Kevin B. Laupland, Jean-Yves Lefrant, Jason A. Roberts, Pragasan Dean Gopalan, Jeffrey Lipman and Gavin M. Joynt
    Citation: Journal of Intensive Care 2022 10:44
  42. High-flow nasal cannula (HFNC) was shown to be non-inferior to noninvasive ventilation (NIV) for preventing reintubation in a general population of high-risk patients. However, some subgroups of high-risk pati...

    Authors: Gonzalo Hernández, Concepción Vaquero, Ramon Ortiz, Laura Colinas, Raul de Pablo, Lourdes Segovia, Maria Luisa Rodriguez, Ana Villasclaras, Juan Francisco Muñoz-Moreno, Fernando Suarez-Sipmann, Alfonso Canabal, Rafael Cuena and Oriol Roca
    Citation: Journal of Intensive Care 2022 10:43