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  1. Recent reports have demonstrated that among patients with subarachnoid hemorrhage (SAH) treated with hypertonic NaCl, resultant hyperchloremia has been associated with the development of acute kidney injury (A...

    Authors: Ofer Sadan, Kai Singbartl, Jacqueline Kraft, Joao McONeil Plancher, Alexander C. M. Greven, Prem Kandiah, Cederic Pimentel, C. L. Hall, Alexander Papangelou, William H. Asbury, John J. Hanfelt and Owen Samuels
    Citation: Journal of Intensive Care 2020 8:32

    The Correction to this article has been published in Journal of Intensive Care 2020 8:66

    The Commentary to this article has been published in Journal of Intensive Care 2020 8:73

  2. Leptospirosis is a potentially fatal zoonosis. It can cause a wide range of symptoms, including diffuse alveolar haemorrhage which occurs in a minority of cases but carries a mortality of over 70%. These patie...

    Authors: James Barnacle, Stefan Gurney, Stephane Ledot and Suveer Singh
    Citation: Journal of Intensive Care 2020 8:31
  3. Candidemia is one of the most life-threatening infections among critically ill patients in the intensive care unit. However, the number of studies on the impact of host- and early treatment-related factors on ...

    Authors: Shingo Ohki, Nobuaki Shime, Tadashi Kosaka and Naohisa Fujita
    Citation: Journal of Intensive Care 2020 8:30
  4. The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. We have collected a total of 26 patients with COVID-19 who required extracorporeal membranous oxygenation (ECMO). The available data from th...

    Authors:
    Citation: Journal of Intensive Care 2020 8:29

    The Correction to this article has been published in Journal of Intensive Care 2020 8:38

  5. Early use of antimicrobials is a critical intervention in the treatment of patients with sepsis. The exact time of initiation is controversial and its early administration may be a difficult task in crowded em...

    Authors: Johana Ascuntar, Deibie Mendoza and Fabián Jaimes
    Citation: Journal of Intensive Care 2020 8:28

    The Letter to the Editor to this article has been published in Journal of Intensive Care 2020 8:52

  6. Few studies have investigated spinal cord autoregulation using near-infrared spectroscopy (NIRS). Here, we assessed spinal cord autoregulation under normal, hypovolemic, and post-fluid resuscitation conditions...

    Authors: Tadayoshi Kurita, Shingo Kawashima, Koji Morita and Yoshiki Nakajima
    Citation: Journal of Intensive Care 2020 8:27
  7. Appropriate antimicrobial dosing is challenging because of changes in pharmacokinetics (PK) parameters and an increase in multidrug-resistant (MDR) organisms in critically ill patients. This study aimed to eva...

    Authors: Tospon Lertwattanachai, Preecha Montakantikul, Viratch Tangsujaritvijit, Pitsucha Sanguanwit, Jetjamnong Sueajai, Saranya Auparakkitanon and Pitchaya Dilokpattanamongkol
    Citation: Journal of Intensive Care 2020 8:26
  8. Neutrophil extracellular traps (NETs) are fibrous structures released from activated neutrophils. NET formation has been reported to be associated with acute respiratory distress syndrome (ARDS). However, ther...

    Authors: Masahiro Ojima, Norihisa Yamamoto, Tomoya Hirose, Shigeto Hamaguchi, Osamu Tasaki, Takashi Kojima, Kazunori Tomono, Hiroshi Ogura and Takeshi Shimazu
    Citation: Journal of Intensive Care 2020 8:25
  9. It is estimated that 5–14% of patients presenting with hemoptysis will have life-threatening hemoptysis, with a reported mortality rate between 9 and 38%. This manuscript provides a comprehensive literature re...

    Authors: Hasmeena Kathuria, Helen M. Hollingsworth, Rajendran Vilvendhan and Christine Reardon
    Citation: Journal of Intensive Care 2020 8:23
  10. Authors: Yohei Okada, Takeshi Unoki, Yujiro Matsuishi, Yuko Egawa, Kei Hayashida and Shigeaki Inoue
    Citation: Journal of Intensive Care 2020 8:22

    The original article was published in Journal of Intensive Care 2020 8:21

  11. Critical comment on the review by Okada et al. on the effect of early versus delayed mobilization because of their definition of early mobilization as mobilization within a week of ICU admission in contrast to...

    Authors: K. Friedrich Kuhn and Stefan J. Schaller
    Citation: Journal of Intensive Care 2020 8:21

    The Letter to the editor response to this article has been published in Journal of Intensive Care 2020 8:22

    The original article was published in Journal of Intensive Care 2019 7:57

  12. Weaning of patients from the mechanical ventilation remains one of the critical decisions in intensive care unit. This study aimed to evaluate the accuracy of thoracic fluid content (TFC) as a predictor of wea...

    Authors: Shymaa Fathy, Ahmed M. Hasanin, Mohamed Raafat, Maha M. A. Mostafa, Ahmed M. Fetouh, Mohamed Elsayed, Esraa M. Badr, Hanan M. Kamal and Ahmed Z. Fouad
    Citation: Journal of Intensive Care 2020 8:20
  13. Several studies have assessed predictors of weaning and extubation outcome in short-term mechanically ventilated patients, but there are only few studies on predictors of weaning from prolonged mechanical vent...

    Authors: Alessandro Ghiani, Joanna Paderewska, Alexandros Sainis, Alexander Crispin, Swenja Walcher and Claus Neurohr
    Citation: Journal of Intensive Care 2020 8:19
  14. Disseminated intravascular coagulation (DIC) is a common complication in sepsis because of crosstalk between the immune system and the coagulation system. Several anticoagulant agents have been tested in an at...

    Authors: Yu Inata
    Citation: Journal of Intensive Care 2020 8:18
  15. A high mortality rate is found among septic patients with disseminated intravascular coagulation (DIC). Anticoagulants have been used for treating septic DIC especially in Japanese clinical settings; however, ...

    Authors: Nobuyuki Yokoyama, Shunsuke Takaki, Masashi Yokose, Kaori Kuwabara, Akiko Anzai, Takako Hamada, Shizuka Kashiwagi, Kenta Okamura, Yoh Sugawara and Takahisa Goto
    Citation: Journal of Intensive Care 2020 8:17
  16. Considering the adverse effects of sleep disturbance in critical care settings, accurate assessment could aid therapy; however, methodological inadequacies mean that no viable option is currently available. Re...

    Authors: Kanae Nagatomo, Tomoyuki Masuyama, Yusuke Iizuka, Jun Makino, Junji Shiotsuka and Masamitsu Sanui
    Citation: Journal of Intensive Care 2020 8:16
  17. Treatment with intravenous paracetamol may impair hemodynamics in critically ill adults. Few data are available in children. The aim of this study was to investigate the frequency, extent, and risk factors of ...

    Authors: Elhanan Nahum, Avichai Weissbach, Eytan Kaplan and Gili Kadmon
    Citation: Journal of Intensive Care 2020 8:14
  18. Along with the recent spread of multidrug-resistant bacteria, outbreaks of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria present a serious challenge to clinicians. β-lactam antibiot...

    Authors: Teiji Sawa, Kunihiko Kooguchi and Kiyoshi Moriyama
    Citation: Journal of Intensive Care 2020 8:13
  19. Neuromuscular blocking agent (NMBA) has been proposed by medical guidelines for early severe acute respiratory distress syndrome (ARDS) because of its survival benefits. However, new studies have provided evid...

    Authors: An Thi Nhat Ho, Setu Patolia and Christophe Guervilly
    Citation: Journal of Intensive Care 2020 8:12
  20. Neutrophil gelatinase-associated lipocalin (NGAL) is a diagnostic marker for acute kidney injury (AKI). NGAL expression is highly induced not only in kidney injury but also in bacterial infection, inflammation...

    Authors: Chieko Mitaka, Chika Ishibashi, Izumi Kawagoe, Takashi Hashimoto, Makoto Takahashi, Daizoh Satoh and Eiichi Inada
    Citation: Journal of Intensive Care 2020 8:11
  21. Clinically significant gastrointestinal bleeding from stress ulcers increases patient mortality in intensive care, and histamine type 2 receptor blockers and proton pump inhibitors as stress ulcer prophylaxes ...

    Authors: Osamu Ogasawara, Taiki Kojima, Mitsunori Miyazu and Kazuya Sobue
    Citation: Journal of Intensive Care 2020 8:10
  22. In the original publication of this article [1], there were several transcription errors in the logistic regression equation model as below

    Authors: Raymond Kao, Fran Priestap and Allan Donner
    Citation: Journal of Intensive Care 2020 8:9

    The original article was published in Journal of Intensive Care 2016 4:16

  23. Studies showed potential benefits of recombinant human-soluble thrombomodulin (rhTM) and antithrombin for treating sepsis associated disseminated intravascular coagulation. However, benefits of their combinati...

    Authors: Jun Suzuki, Yusuke Sasabuchi, Shuji Hatakeyama, Hiroki Matsui, Teppei Sasahara, Yuji Morisawa, Toshiyuki Yamada and Hideo Yasunaga
    Citation: Journal of Intensive Care 2020 8:8
  24. Predisposing conditions and risk modifiers instead of causes and risk factors have recently been used as alternatives to identify patients at a risk of acute respiratory distress syndrome (ARDS). However, data...

    Authors: Hiroki Iriyama, Toshikazu Abe, Shigeki Kushimoto, Seitaro Fujishima, Hiroshi Ogura, Atsushi Shiraishi, Daizoh Saitoh, Toshihiko Mayumi, Toshio Naito, Akira Komori, Toru Hifumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Yasuhiro Otomo, Kohji Okamoto…
    Citation: Journal of Intensive Care 2020 8:7
  25. Because critical illness survivors frequently experience several long-term psychological impairments altering quality of life after ICU, there is a trend towards increasing follow-up care, mainly via ICU follo...

    Authors: Johan H. Vlake, Michel E. van Genderen, Anna Schut, Martijn Verkade, Evert-Jan Wils, Diederik Gommers and Jasper van Bommel
    Citation: Journal of Intensive Care 2020 8:6
  26. Sepsis is a global health priority. Interventions to reduce the burden of sepsis need to be both effective and cost-effective. We performed a systematic review of the literature on health economic evaluations ...

    Authors: Alisa M. Higgins, Joanne E. Brooker, Michael Mackie, D. Jamie Cooper and Anthony H. Harris
    Citation: Journal of Intensive Care 2020 8:5
  27. Circadian clock alterations were poorly reported in trauma patients, although they have a critical role in human physiology. Core body temperature is a clinical variable regulated by the circadian clock. Our o...

    Authors: Aurélien Culver, Benjamin Coiffard, François Antonini, Gary Duclos, Emmanuelle Hammad, Coralie Vigne, Jean-Louis Mege, Karine Baumstarck, Mohamed Boucekine, Laurent Zieleskiewicz and Marc Leone
    Citation: Journal of Intensive Care 2020 8:4
  28. Sepsis is the most common cause of premature death among patients with systemic lupus erythematosus (SLE) aged ≤ 50 years in the United States, and infection is the most common cause of admission to the ICU am...

    Authors: Lavi Oud
    Citation: Journal of Intensive Care 2020 8:3
  29. In the original publication of this article [1], the first author’s name should be changed from Alexander Fletcher Sandersjöö to Alexander Fletcher-Sandersjöö. The family name of the author is Fletcher-Sanders...

    Authors: Alexander Fletcher-Sandersjöö, Jiri Bartek Jr, Eric Peter Thelin, Anders Eriksson, Adrian Elmi-Terander, Mikael Broman and Bo-Michael Bellander
    Citation: Journal of Intensive Care 2020 8:2

    The original article was published in Journal of Intensive Care 2017 5:27

  30. Dexmedetomidine has been reported to improve organ dysfunction in critically ill patients. In a recent randomized controlled trial (Dexmedetomidine for Sepsis in Intensive Care Unit (ICU) Randomized Evolution ...

    Authors: Tsuyoshi Nakashima, Kyohei Miyamoto, Nozomu Shima, Seiya Kato, Yu Kawazoe, Yoshinori Ohta, Takeshi Morimoto and Hitoshi Yamamura
    Citation: Journal of Intensive Care 2020 8:1
  31. Recent studies have suggested that anticoagulant therapy does not confer a survival benefit overall in sepsis, but might be beneficial in sepsis-associated disseminated intravascular coagulation (DIC). In part...

    Authors: Takashi Ito, Takaaki Totoki, Yayoi Yokoyama, Tomotsugu Yasuda, Hiroaki Furubeppu, Shingo Yamada, Ikuro Maruyama and Yasuyuki Kakihana
    Citation: Journal of Intensive Care 2019 7:63
  32. Non-convulsive status epilepticus (NCSE) is present in 10–30% of ICU patients with altered mental status (AMS) and is associated to poor outcomes. To our knowledge, there is no data describing the prevalence a...

    Authors: Cristina Gutierrez, Merry Chen, Lei Feng and Sudhakar Tummala
    Citation: Journal of Intensive Care 2019 7:62
  33. Skeletal muscle atrophy commonly occurs in critically ill patients, and decreased muscle mass is associated with worse clinical outcomes. Muscle mass can be assessed using various tools, including ultrasound a...

    Authors: Nobuto Nakanishi, Rie Tsutsumi, Yoshihiro Okayama, Takuya Takashima, Yoshitoyo Ueno, Taiga Itagaki, Yasuo Tsutsumi, Hiroshi Sakaue and Jun Oto
    Citation: Journal of Intensive Care 2019 7:61
  34. The aim of the study was to determine opinions and knowledge regarding the process of obtaining informed consent to participate in observational research in pediatric intensive care.

    Authors: Jessica Hodson, Christiana Garros, Jodie Jensen, Jonathan P. Duff, Gonzalo Garcia Guerra and Ari R. Joffe
    Citation: Journal of Intensive Care 2019 7:60
  35. Critically ill traumatic brain injury (TBI) patients experience extensive muscle damage during their stay in the intensive care unit. Neuromuscular electrical stimulation (NMES) has been considered a promising...

    Authors: Paulo Eugênio Silva, Rita de Cássia Marqueti, Karina Livino-de-Carvalho, Amaro Eduardo Tavares de Araujo, Joana Castro, Vinicius Maldaner da Silva, Luciana Vieira, Vinicius Carolino Souza, Lucas Ogura Dantas, Gerson Cipriano Jr, Otávio Tolêdo Nóbrega, Nicolas Babault and Joao Luiz Quagliotti Durigan
    Citation: Journal of Intensive Care 2019 7:59
  36. Serial lactate measurement is found to predict mortality in septic shock. Majority of patients with perforation peritonitis for emergency laparotomy are in sepsis and mortality rate is substantial. However, la...

    Authors: S. P. Jobin, Souvik Maitra, Dalim Kumar Baidya, Rajeshwari Subramaniam, Ganga Prasad and Vathulru Seenu
    Citation: Journal of Intensive Care 2019 7:58
  37. This systematic review and meta-analysis of randomized clinical trials aimed to investigate the efficacy of early mobilization among critically ill adult patients.

    Authors: Yohei Okada, Takeshi Unoki, Yujiro Matsuishi, Yuko Egawa, Kei Hayashida and Shigeaki Inoue
    Citation: Journal of Intensive Care 2019 7:57

    The Letter to the Editor to this article has been published in Journal of Intensive Care 2020 8:21

  38. Diaphragm atrophy is observed in mechanically ventilated patients. However, the atrophy is not investigated in other respiratory muscles. Therefore, we conducted a two-center prospective observational study to...

    Authors: Nobuto Nakanishi, Jun Oto, Yoshitoyo Ueno, Emiko Nakataki, Taiga Itagaki and Masaji Nishimura
    Citation: Journal of Intensive Care 2019 7:56
  39. The burden of sepsis is highest in low- and middle-income countries, though the management of sepsis in these settings is poorly characterized. Therefore, the objective of this study was to assess the early ma...

    Authors: Kristina E. Rudd, Viriya Hantrakun, Ranjani Somayaji, Suchart Booraphun, Chaiyaporn Boonsri, Annette L. Fitzpatrick, Nicholas P. J. Day, Prapit Teparrukkul, Direk Limmathurotsakul and T. Eoin West
    Citation: Journal of Intensive Care 2019 7:55
  40. A spontaneous breathing trial (SBT) is a major diagnostic tool to predict successfully extubation in patients. Several factors may lead to weaning failure, including the degree of lung aeration loss and diaphr...

    Authors: Jing Xia, Chuan-Yun Qian, Li Yang, Mei-Ju Li, Xiao-Xue Liu, Ting Yang and Qin Lu
    Citation: Journal of Intensive Care 2019 7:54
  41. Gait independence is one of the most important factors related to returning home from the hospital for patients treated in the intensive care unit (ICU), but the factors affecting gait independence have not be...

    Authors: Shinichi Watanabe, Toru Kotani, Shunsuke Taito, Kohei Ota, Kenzo Ishii, Mika Ono, Hajime Katsukawa, Ryo Kozu, Yasunari Morita, Ritsuro Arakawa and Shuichi Suzuki
    Citation: Journal of Intensive Care 2019 7:53
  42. Traditional capillary refill time (CRT) is a manual measurement that is commonly used by clinicians to identify deterioration in peripheral perfusion status. Our study compared a novel method of measuring peri...

    Authors: Koichiro Shinozaki, Lee S. Jacobson, Kota Saeki, Hideaki Hirahara, Naoki Kobayashi, Steve Weisner, Julianne M. Falotico, Timmy Li, Junhwan Kim and Lance B. Becker
    Citation: Journal of Intensive Care 2019 7:52
  43. The majority of patients with hemorrhagic stroke experience enhanced renal clearance or augmented renal clearance (ARC). The purpose of this study was to determine the impact of enhanced renal clearance or ARC...

    Authors: Kathryn A. Morbitzer, Denise H. Rhoney, Kelly A. Dehne and J. Dedrick Jordan
    Citation: Journal of Intensive Care 2019 7:51
  44. Ventilator weaning protocols have been shown to reduce the duration of mechanical ventilation (MV), intensive care unit length of stay, and resource use. However, weaning protocols have not significantly affec...

    Authors: Kenichi Nitta, Kazufumi Okamoto, Hiroshi Imamura, Katsunori Mochizuki, Hiroshi Takayama, Hiroshi Kamijo, Mayumi Okada, Kanako Takeshige, Yuichiro Kashima and Takahisa Satou
    Citation: Journal of Intensive Care 2019 7:50
  45. Alcohol withdrawal syndrome (AWS) is commonly treated in medical ICUs and typically requires high resource utilization. Dexmedetomidine for AWS has not been extensively investigated, and guidelines regarding i...

    Authors: Ekaterina R. Yavarovich, Maythawee Bintvihok, Justin C. McCarty, Janis L. Breeze and Peter LaCamera
    Citation: Journal of Intensive Care 2019 7:49
  46. Frailty status is recognized as an important parameter in critically ill elderly patients, but nothing is known about outcomes in non-frail patients regarding the development of frailty or frailty and death af...

    Authors: Yoann Launey, Hervé Jacquet, Matthieu Arnouat, Chloe Rousseau, Nicolas Nesseler and Philippe Seguin
    Citation: Journal of Intensive Care 2019 7:48
  47. Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states. Medical literature has both explicitly stated and implied th...

    Authors: Roshan Bisarya, Deena Shaath, Arman Pirzad, Lewis Satterwhite, Jianghua He and Steven Q. Simpson
    Citation: Journal of Intensive Care 2019 7:47
  48. Early recognition of sepsis is challenging, and diagnostic criteria have changed repeatedly. We assessed the robustness of sepsis-3 criteria in intensive care unit (ICU) patients.

    Authors: Diana M. Verboom, Jos F. Frencken, David S. Y. Ong, Janneke Horn, Tom van der Poll, Marc J. M. Bonten, Olaf L. Cremer and Peter M. C. Klein Klouwenberg
    Citation: Journal of Intensive Care 2019 7:46