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  1. Tigecycline has in vitro bacteriostatic activity against a broad spectrum of bacteria, including carbapenem-resistant Gram-negative bacteria (CR-GNB). However, the role of tigecycline in treatment of nosocomia...

    Authors: Kuang-Yao Yang, Chung-Kan Peng, Chau-Chyun Sheu, Yu-Chao Lin, Ming-Cheng Chan, Sheng-Huei Wang, Chia-Min Chen, Chih-Yu Chen, Zhe-Rong Zheng and Jia-Yih Feng
    Citation: Journal of Intensive Care 2023 11:1
    Content type: Research Published on:

  2. Extracorporeal membrane oxygenation (ECMO) is an integral method of life support in critically ill patients with severe cardiopulmonary failure; however, such patients generally require prolonged mechanical ve...

    Authors: Ryota Nukiwa, Akinori Uchiyama, Aiko Tanaka, Tetsuhisa Kitamura, Ryota Sakaguchi, Yoshimitsu Shimomura, Suguru Ishigaki, Yusuke Enokidani, Tomonori Yamashita, Yukiko Koyama, Takeshi Yoshida, Natsuko Tokuhira, Naoya Iguchi, Yasushi Shintani, Shigeru Miyagawa and Yuji Fujino
    Citation: Journal of Intensive Care 2022 10:56
    Content type: Research Published on:

  3. Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory set...

    Authors: Laura Amado-Rodríguez, Raquel Rodríguez-Garcia, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, John G. Laffey and Guillermo M. Albaiceta
    Citation: Journal of Intensive Care 2022 10:55
    Content type: Research Published on:

  4. The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. The objective was to determine how delirium subtypes are associated with hospital morta...

    Authors: Lisa Smit, Eveline J. A. Wiegers, Zoran Trogrlic, Wim J. R. Rietdijk, Diederik Gommers, Erwin Ista and Mathieu van der Jagt
    Citation: Journal of Intensive Care 2022 10:54
    Content type: Research Published on:

  7. The coronavirus disease 2019 (COVID-19) pandemic has disrupted critical care services worldwide. Examining how critical care systems responded to the COVID-19 pandemic on a national level will be useful in set...

    Authors: Hiroyuki Ohbe, Yusuke Sasabuchi, Hiroki Matsui and Hideo Yasunaga
    Citation: Journal of Intensive Care 2022 10:51
    Content type: Research Published on:

  8. Given the available clinical evidence through the literature search when the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 was being created, we suggested administering v...

    Authors:
    Citation: Journal of Intensive Care 2022 10:50
    Content type: Letter Published on:

  9. The appropriate duration of antibiotic treatment in patients with bacterial sepsis remains unclear. The purpose of this study was to evaluate the association of a shorter course of antibiotics on 28-day mortal...

    Authors: Nozomi Takahashi, Taro Imaeda, Taka‑aki Nakada, Takehiko Oami, Toshikazu Abe, Yasuo Yamao, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Asako Matsushima and Kiyohide Fushimi
    Citation: Journal of Intensive Care 2022 10:49
    Content type: Research Published on:

  10. Fontan surgery with cardiopulmonary bypass (CPB) causes tremendous systemic stress and inflammatory responses, affecting postoperative organ function, morbidity, and mortality. Although this reaction triggers ...

    Authors: Jacek Kolcz, Elzbieta Karnas, Zbigniew Madeja and Ewa K. Zuba-Surma
    Citation: Journal of Intensive Care 2022 10:48
    Content type: Research Published on:

  12. Acute respiratory distress syndrome (ARDS), a prevalent cause of admittance to intensive care units, is associated with high mortality. Prone positioning has been proven to improve the outcomes of moderate to ...

    Authors: Hongling Zhang, Zhengdong Liu, Huaqing Shu, Yuan Yu, Xiaobo Yang, Ruiting Li, Jiqian Xu, Xiaojing Zou and You Shang
    Citation: Journal of Intensive Care 2022 10:46
    Content type: Review Published on:

  13. There is little known about the contribution of microRNAs (miRNAs) in the recovery from acute kidney injury (AKI). This study aimed to discover and validate miRNA profiles for predicting renal recovery from se...

    Authors: Thanawat Phulkerd, Tanat Lertussavavivat, Umaporn Limothai, Sadudee Peerapornratana, Win Kulvichit, Nuttha Lumlertgul, Kriang Tungsanga, Somchai Eiam-Ong, Yingyos Avihingsanon and Nattachai Srisawat
    Citation: Journal of Intensive Care 2022 10:45
    Content type: Research Published on:

  14. Up to 11% of critically ill patients with sepsis have an unknown source, where the pathogen and site of infection are unclear. The aim of this scoping review is to document currently reported diagnostic criter...

    Authors: Lowell Ling, Oliver Oi Yat Mui, Kevin B. Laupland, Jean-Yves Lefrant, Jason A. Roberts, Pragasan Dean Gopalan, Jeffrey Lipman and Gavin M. Joynt
    Citation: Journal of Intensive Care 2022 10:44
    Content type: Research Published on:

  15. High-flow nasal cannula (HFNC) was shown to be non-inferior to noninvasive ventilation (NIV) for preventing reintubation in a general population of high-risk patients. However, some subgroups of high-risk pati...

    Authors: Gonzalo Hernández, Concepción Vaquero, Ramon Ortiz, Laura Colinas, Raul de Pablo, Lourdes Segovia, Maria Luisa Rodriguez, Ana Villasclaras, Juan Francisco Muñoz-Moreno, Fernando Suarez-Sipmann, Alfonso Canabal, Rafael Cuena and Oriol Roca
    Citation: Journal of Intensive Care 2022 10:43
    Content type: Research Published on:

  16. Recently, a letter to the editor was published to comment on the 5A score which is the prediction model for accidental hypothermia patients comparing the HOPE score. In this letter, we responded to the comment...

    Authors: Yohei Okada, Tasuku Matsuyama, Kei Hayashida, Shuhei Takauji, Jun Kanda and Shoji Yokobori
    Citation: Journal of Intensive Care 2022 10:42
    Content type: Letter to the Editor Published on:

  17. The effect of ICU admission time on patient outcomes has been shown to be controversial in several studies from a number of countries. The imbalance between ICU staffing and medical resources during off-hours ...

    Authors: Yu Namikata, Yoshinori Matsuoka, Jiro Ito, Ryutaro Seo, Yasukazu Hijikata, Takahiro Itaya, Kenjiro Ouchi, Haruka Nishida, Yosuke Yamamoto and Koichi Ariyoshi
    Citation: Journal of Intensive Care 2022 10:41
    Content type: Research Published on:

  18. Diaphragm fiber atrophy has been evidenced after short periods of mechanical ventilation (MV) and related to critical illness-associated diaphragm weakness. Atrophy is described as a decrease in diaphragm fibe...

    Authors: Irene Dot, Purificación Pérez-Terán, Albert Francés, Yolanda Díaz, Clara Vilà-Vilardell, Anna Salazar-Degracia, Roberto Chalela, Esther Barreiro, Alberto Rodriguez-Fuster, Joan Ramon Masclans and Judith Marin-Corral
    Citation: Journal of Intensive Care 2022 10:40
    Content type: Research Published on:

  19. Post-resuscitation hemodynamic level is associated with outcomes. This study was conducted to investigate if post-resuscitation diastolic blood pressure (DBP) is a favorable prognostic factor.

    Authors: Chien-Yu Chi, Min-Shan Tsai, Li-Kuo Kuo, Hsin-Hui Hsu, Wei-Chun Huang, Chih-Hung Lai, Herman Chih-Heng Chang, Chu-Lin Tsai and Chien-Hua Huang
    Citation: Journal of Intensive Care 2022 10:39
    Content type: Research Published on:

  20. In late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is responsible for coronavirus disease (COVID-19), was identified as the new pathogen to lead pneumonia in Wuhan, China, whi...

    Authors: Shahideh Amini, Aysa Rezabakhsh, Javad Hashemi, Fatemeh Saghafi, Hossein Azizi, Antoni Sureda, Solomon Habtemariam, Hamid Reza Khayat Kashani, Zahra Hesari and Adeleh Sahebnasagh
    Citation: Journal of Intensive Care 2022 10:38
    Content type: Review Published on:

  21. The 5A score predicts in-hospital mortality of patients suffering from accidental hypothermia, including those not in cardiac arrest. The HOPE score was specifically developed to predict survival for the subgr...

    Authors: Mathieu Pasquier, Olivier Hugli, Nicolas Hall, Valentin Rousson and Tomasz Darocha
    Citation: Journal of Intensive Care 2022 10:37
    Content type: Letter to the Editor Published on:

  23. Septic shock is a common and life-threatening condition that requires intensive care. Intensive care units (ICUs) in Japan are classified into ICUs and high-dependency care units (HDUs), depending on presence ...

    Authors: Koji Endo, Kayoko Mizuno, Tomotsugu Seki, Woo Jin Joo, Chikashi Takeda, Masato Takeuchi and Koji Kawakami
    Citation: Journal of Intensive Care 2022 10:35
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Intensive Care 2022 10:47

  24. The aim of the study was to assess the feasibility of a standardized tracheostomy decannulation protocol in patients with prolonged tracheostomy referred to a rehabilitation hospital.

    Authors: Ting Zhou, Jianjun Wang, Chenxi Zhang, Bin Zhang, Haiming Guo, Bo Yang, Qing Li, Jingyi Ge, Yi Li, Guangyu Niu, Hua Gao and Hongying Jiang
    Citation: Journal of Intensive Care 2022 10:34
    Content type: Research Published on:

  25. Sepsis is the leading cause of death worldwide. Although the mortality of sepsis patients has been decreasing over the past decade, the trend of medical costs and cost-effectiveness for sepsis treatment remain...

    Authors: Takehiko Oami, Taro Imaeda, Taka‑aki Nakada, Toshikazu Abe, Nozomi Takahashi, Yasuo Yamao, Satoshi Nakagawa, Hiroshi Ogura, Nobuaki Shime, Yutaka Umemura, Asako Matsushima and Kiyohide Fushimi
    Citation: Journal of Intensive Care 2022 10:33
    Content type: Research Published on:

  26. The joint committee of the Japanese Society of Intensive Care Medicine/Japanese Respiratory Society/Japanese Society of Respiratory Care Medicine on ARDS Clinical Practice Guideline has created and released th...

    Authors: Sadatomo Tasaka, Shinichiro Ohshimo, Muneyuki Takeuchi, Hideto Yasuda, Kazuya Ichikado, Kenji Tsushima, Moritoki Egi, Satoru Hashimoto, Nobuaki Shime, Osamu Saito, Shotaro Matsumoto, Eishu Nango, Yohei Okada, Kenichiro Hayashi, Masaaki Sakuraya, Mikio Nakajima…
    Citation: Journal of Intensive Care 2022 10:32
    Content type: Guideline Published on:

  27. A fast and reliable left ventricular outflow diameter (LVOTd) estimation may aid in quickly estimating cardiac output. However, obtaining a correct LVOTd can be difficult in intensive care patients, potentiall...

    Authors: Eline G. M. Cox, Jacqueline Koeze, Iwan C. C. van der Horst and Renske Wiersema
    Citation: Journal of Intensive Care 2022 10:31
    Content type: Letter to the Editor Published on:

  28. Target temperature management (TTM) is an effective component of treating out-of-hospital cardiac arrest (OHCA) after return of spontaneous circulation in conventional cardiopulmonary resuscitation. However, t...

    Authors: Toshihiro Sakurai, Tadashi Kaneko, Shu Yamada and Takeshi Takahashi
    Citation: Journal of Intensive Care 2022 10:30
    Content type: Research Published on:

  29. Cardiac dysfunction, a common complication of sepsis, is associated with increased mortality. However, its risk factors are poorly understood, and a predictive model might help in the management of cardiac dys...

    Authors: Jiangquan Yu, Ruiqiang Zheng, Penglei Yang and Daxin Wang
    Citation: Journal of Intensive Care 2022 10:29
    Content type: Research Published on:

  30. In acute pancreatitis (AP), microcirculatory dysfunction and leukocyte activation contribute to organ damage, inflammation, and mortality. Given the role of macrophage activation, monocyte recruitment, and mic...

    Authors: Philipp A. Reuken, Jonathan F. Brozat, Stefanie Quickert, Oluwatomi Ibidapo-obe, Johanna Reißing, Anika Franz, Sven Stengel, Ulf K.-M. Teichgräber, Michael Kiehntopf, Christian Trautwein, Andreas Stallmach, Alexander Koch and Tony Bruns
    Citation: Journal of Intensive Care 2022 10:28
    Content type: Research Published on:

  32. We validated an adapted form of the Pediatric Sepsis Score (aPSS), a disease-specific severity score available within 60 min of PICU admission, in children with invasive infection. aPSS consist of all componen...

    Authors: Navin P. Boeddha, Luregn J. Schlapbach, Idse H. Visser and Nicolaas J. G. Jansen
    Citation: Journal of Intensive Care 2022 10:26
    Content type: Letter to the Editor Published on:

  33. Hypoalbuminemia at the initiation of continuous renal replacement therapy (CRRT) is a risk factor for poor patient outcomes. However, it is unknown whether the patterns of changes in serum albumin levels durin...

    Authors: Harin Rhee, Gum Sook Jang, Sungmi Kim, Wanhee Lee, Hakeong Jeon, Da Woon Kim, Byung-min Ye, Hyo Jin Kim, Min Jeong Kim, Seo Rin Kim, Il Young Kim, Sang Heon Song, Eun Young Seong, Dong Won Lee and Soo Bong Lee
    Citation: Journal of Intensive Care 2022 10:25
    Content type: Research Published on:

  34. The 5A score including five components “Age, Activities of daily living, Arrest, Acidemia and Albumin” was developed as an easy-to-use screening tool for predicting in-hospital mortality among patients with ac...

    Authors: Yohei Okada, Tasuku Matsuyama, Kei Hayashida, Shuhei Takauji, Jun Kanda and Shoji Yokobori
    Citation: Journal of Intensive Care 2022 10:24
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Intensive Care 2022 10:27

  35. Clinical impact of preoperative diaphragm dysfunction on lung transplantation has not been studied. We aimed to evaluate how preoperative diaphragm dysfunction affects clinical outcomes and ventilation functio...

    Authors: Sungchul Huh, Woo Hyun Cho, Dohyung Kim, Bong Soo Son and Hye Ju Yeo
    Citation: Journal of Intensive Care 2022 10:23
    Content type: Research Published on:

  36. For patients admitted to the intensive care unit (ICU) with sepsis, mobilization therapy during ICU stay can improve their outcomes during and after the ICU stay. However, little is known about the optimal tim...

    Authors: Keibun Liu, Junichiro Shibata, Kiyoyasu Fukuchi, Kunihiko Takahashi, Tomohiro Sonoo, Takayuki Ogura and Tadahiro Goto
    Citation: Journal of Intensive Care 2022 10:22
    Content type: Research Published on:

  37. Levetiracetam pharmacokinetics is extensively altered in critically ill patients with augmented renal clearance (ARC). Consequently, the dosage regimens commonly used in clinical practice may not be sufficient...

    Authors: Idoia Bilbao-Meseguer, Helena Barrasa, Alicia Rodríguez-Gascón, Eduardo Asín-Prieto, Javier Maynar, José Ángel Sánchez-Izquierdo, María Ángeles Solinís and Arantxazu Isla
    Citation: Journal of Intensive Care 2022 10:21
    Content type: Research Published on:

  38. Palliative care is an interdisciplinary care to optimize physical, psychosocial, and spiritual symptoms of patients and their families whose quality of life is impaired by serious, life-limiting illness. In 20...

    Authors: Kaori Ito, Naomi George, Jennifer Wilson, Jason Bowman, Emily Aaronson and Kei Ouchi
    Citation: Journal of Intensive Care 2022 10:20
    Content type: Review Published on:

  39. Tracheostomy is commonly performed in critically ill patients because of its clinical advantages over prolonged translaryngeal endotracheal intubation. Early tracheostomy has been demonstrated to reduce the du...

    Authors: Aiko Tanaka, Akinori Uchiyama, Tetsuhisa Kitamura, Ryota Sakaguchi, Sho Komukai, Tasuku Matsuyama, Takeshi Yoshida, Natsuko Tokuhira, Naoya Iguchi and Yuji Fujino
    Citation: Journal of Intensive Care 2022 10:19
    Content type: Research Published on:

  40. It is currently unknown how widespread is the practice of palliative care in intensive care units (ICUs) in Japan. This study aimed to determine evaluate the delivery and self-reported practice of palliative c...

    Authors: Yuko Igarashi, Yuta Tanaka, Kaori Ito, Mitsunori Miyashita, Satomi Kinoshita, Akane Kato and Yoshiyuki Kizawa
    Citation: Journal of Intensive Care 2022 10:18
    Content type: Research Published on:

  41. The end-tidal partial pressure of carbon dioxide (PETCO2) can be used to estimate the arterial partial pressure of carbon dioxide (PaCO2) in patients who undergo mechanical ventilation via endotracheal intubation...

    Authors: Masaaki Sakuraya, Eri Douno, Wakana Iwata, Akihiro Takaba, Kosuke Hadama, Natsuki Kawamura, Toshinori Maezawa, Kei Iwamoto, Yuya Yoshino and Kenichi Yoshida
    Citation: Journal of Intensive Care 2022 10:17
    Content type: Research Published on:

  42. Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In this revie...

    Authors: William Spears, Asim Mian and David Greer
    Citation: Journal of Intensive Care 2022 10:16
    Content type: Review Published on:

  43. Healthcare providers working for cardiovascular intensive care often face challenges and they play an essential role in palliative care and end-of-life care because of the high mortality rates in the cardiac i...

    Authors: Yoshimitsu Takaoka, Yasuhiro Hamatani, Tatsuhiro Shibata, Shogo Oishi, Akemi Utsunomiya, Fujimi Kawai, Nobuyuki Komiyama and Atsushi Mizuno
    Citation: Journal of Intensive Care 2022 10:15
    Content type: Review Published on:

  44. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is the leading cause of death among patients with IPF. However, there is no established treatment for this condition. Hence, we aimed to investigate...

    Authors: Nobuyasu Awano, Taisuke Jo, Takehiro Izumo, Minoru Inomata, Kojiro Morita, Hiroki Matsui, Kiyohide Fushimi, Hirokazu Urushiyama, Takahide Nagase and Hideo Yasunaga
    Citation: Journal of Intensive Care 2022 10:14
    Content type: Research Published on:

  45. Sepsis is a life-threatening organ dysfunction. A fast diagnosis is crucial for patient management. Proteins that are synthesized during the inflammatory response can be used as biomarkers, helping in a rapid ...

    Authors: Valentino D’Onofrio, Dries Heylen, Murih Pusparum, Inge Grondman, Johan Vanwalleghem, Agnes Meersman, Reinoud Cartuyvels, Peter Messiaen, Leo A. B. Joosten, Mihai G. Netea, Dirk Valkenborg, Gökhan Ertaylan and Inge C. Gyssens
    Citation: Journal of Intensive Care 2022 10:13
    Content type: Research Published on:

  46. Even an ultraprotective ventilation strategy in severe acute respiratory distress syndrome (ARDS) patients treated with extracorporeal membrane oxygenation (ECMO) might induce ventilator-induced lung injury an...

    Authors: Peter T. Graf, Christoph Boesing, Isabel Brumm, Jonas Biehler, Kei Wieland Müller, Manfred Thiel, Paolo Pelosi, Patricia R. M. Rocco, Thomas Luecke and Joerg Krebs
    Citation: Journal of Intensive Care 2022 10:12
    Content type: Research Published on:

  48. Although numerous studies have investigated out-of-hospital cardiac arrest, few studies have been conducted on in-hospital cardiac arrest (IHCA). Knowledge of the nationwide epidemiology of IHCA in Japan, with...

    Authors: Hiroyuki Ohbe, Takashi Tagami, Kazuaki Uda, Hiroki Matsui and Hideo Yasunaga
    Citation: Journal of Intensive Care 2022 10:10
    Content type: Research Published on:

  49. The evidence about the best body position to prevent ventilator-associated pneumonia (VAP) is unclear. The aim of this study was to know what the best body position is to prevent VAP, shorten the length of int...

    Authors: Diana P. Pozuelo-Carrascosa, Ana Isabel Cobo-Cuenca, Juan Manuel Carmona-Torres, Jose Alberto Laredo-Aguilera, Esmeralda Santacruz-Salas and Ruben Fernandez-Rodriguez
    Citation: Journal of Intensive Care 2022 10:9
    Content type: Review Published on:

  50. Although the effect of thiamine alone or in combination with vitamin C has been studied in multiple trials (RCT and interventional studies), their results are inconsistent. This meta-analysis aimed to assess i...

    Authors: Nafiseh Shokri-mashhadi, Ali Aliyari, Zahra Hajhashemy, Saeed Saadat and Mohammad Hossein Rouhani
    Citation: Journal of Intensive Care 2022 10:8
    Content type: Review Published on:
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  • ISSN: 2052-0492 (electronic)

Journal of Intensive Care

ISSN: 2052-0492