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  1. We encountered markedly elevated procalcitonin (PCT) among pediatric patients during the early postoperative period of open heart surgery. The purpose of this study is to investigate what factors are associate...

    Authors: Etsuko Minami, Shoji Ito, Takeshi Sugiura, Yoshihito Fujita, Hiroshi Sasano and Kazuya Sobue
    Citation: Journal of Intensive Care 2014 2:38
  2. Probiotics have currently been widely used in patients undergoing various types of surgeries and improved their clinical outcomes, while data in pediatric cardiac surgery have been lacking. We investigated the...

    Authors: Takako Umenai, Nobuaki Shime, Takashi Asahara, Koji Nomoto and Toshiyuki Itoi
    Citation: Journal of Intensive Care 2014 2:36
  3. This study was performed to assess the value of procalcitonin (PCT) for the differential diagnosis between infectious and non-infectious systemic inflammatory response syndrome (SIRS) after cardiac surgery.

    Authors: Dong Zhao, Jianxin Zhou, Go Haraguchi, Hirokuni Arai and Chieko Mitaka
    Citation: Journal of Intensive Care 2014 2:35
  4. To prevent endotracheal tube (ETT)-related complications during mechanical ventilation, ETT cuff pressure should be kept within proper range. In clinical settings, cuff pressure often decreases from target val...

    Authors: Shota Asai, Asuka Motoyama, Yuri Matsumoto, Hiroyuki Konami, Hideaki Imanaka and Masaji Nishimura
    Citation: Journal of Intensive Care 2014 2:34
  5. In a rural region with few medical resources, we have promoted the strategy that if an out-of-hospital cardiac arrest (OHCA) patient is likely reversible, he or she should be transported directly from the scen...

    Authors: Katsunori Mochizuki, Hiroshi Imamura, Tomomi Iwashita and Kazufumi Okamoto
    Citation: Journal of Intensive Care 2014 2:33
  6. Frantic efforts have been made up to this date to derive consensus for estimating renal function in critically ill patients, only to open the Pandora's box. This article tries to explore the various methods av...

    Authors: Sham Sunder, Rajesh Jayaraman, Himanshu Sekhar Mahapatra, Satyanand Sathi, Venkata Ramanan, Prabhu Kanchi, Anurag Gupta, Sunil Kumar Daksh and Pranit Ram
    Citation: Journal of Intensive Care 2014 2:31
  7. Thrombomodulin alfa (TM-α, recombinant thrombomodulin) significantly improved disseminated intravascular coagulation (DIC) when compared with heparin therapy in a phase III study. Post-marketing surveillance o...

    Authors: Yutaka Eguchi, Satoshi Gando, Hiroyasu Ishikura, Daizoh Saitoh, Jun Mimuro, Hoyu Takahashi, Isao Kitajima, Hajime Tsuji, Tadashi Matsushita, Ryuichi Tsujita, Osamu Nagao and Yoichi Sakata
    Citation: Journal of Intensive Care 2014 2:30
  8. This study aimed to assess the performance of the Simplified Acute Physiology Score 3 (SAPS 3) as a predictor of ICU mortality in critically ill patients of different case mixes admitted to an intensive care u...

    Authors: Aaron Mark R Hernandez and Jose Emmanuel M Palo
    Citation: Journal of Intensive Care 2014 2:29
  9. The aim of this study was to investigate effects of basic life support (BLS) training on willingness of single rescuers to make emergency calls during out-of-hospital cardiac arrests (OHCAs) with no available ...

    Authors: Keiko Hirose, Miki Enami, Hiroki Matsubara, Takahisa Kamikura, Yutaka Takei and Hideo Inaba
    Citation: Journal of Intensive Care 2014 2:28
  10. Although Acute Kidney Injury Network (AKIN) staging is widely used, it has been suggested that classification using serum creatinine levels, which fluctuate because of fluid balance, is not always appropriate ...

    Authors: Yu Horiguchi, Akinori Uchiyama, Naoya Iguchi, Kanaki Sakai, Daisuke Hiramatsu, Kazuyoshi Ueta, Noriyuki Ohta and Yuji Fujino
    Citation: Journal of Intensive Care 2014 2:26
  11. Extravascular lung water (EVLW), as measured by the thermodilution method, reflects the extent of pulmonary edema. Currently, there are no clinically effective treatments for preventing increases in pulmonary ...

    Authors: Tadashi Kaneko, Yoshikatsu Kawamura, Tsuyoshi Maekawa, Takashi Tagami, Toshiaki Nakamura, Nobuyuki Saito, Yasuhide Kitazawa, Hiroyasu Ishikura, Manabu Sugita, Kazuo Okuchi, Hiroshi Rinka, Akihiro Watanabe, Yoichi Kase, Shigeki Kushimoto, Hiroo Izumino, Takashi Kanemura…
    Citation: Journal of Intensive Care 2014 2:25
  12. Acute respiratory distress syndrome (ARDS) is characterized by the increased pulmonary permeability secondary to diffuse alveolar inflammation and injuries of several origins. Especially, the distinction betwe...

    Authors: Kenichiro Morisawa, Shigeki Fujitani, Yasuhiko Taira, Shigeki Kushimoto, Yasuhide Kitazawa, Kazuo Okuchi, Hiroyasu Ishikura, Teruo Sakamoto, Takashi Tagami, Junko Yamaguchi, Manabu Sugita, Yoichi Kase, Takashi Kanemura, Hiroyuki Takahashi, Yuuichi Kuroki, Hiroo Izumino…
    Citation: Journal of Intensive Care 2014 2:24
  13. Proper fluid management is crucial for the management of critically ill patients. However, there is a continuing debate about the choice of the fluid, i.e., crystalloid vs. colloid. Colloid solution is theoret...

    Authors: Daisuke Toyoda, Shigeo Shinoda and Yoshifumi Kotake
    Citation: Journal of Intensive Care 2014 2:23
  14. Disorders of the urea cycle are secondary to a defect in the system that converts ammonia into urea, resulting in accumulation of ammonia and other products. This results in encephalopathy, coma, and death if ...

    Authors: MarcelCerqueira Cesar Machado and Fabiano Pinheiro da Silva
    Citation: Journal of Intensive Care 2014 2:22
  15. Infusion fluids may be contaminated with different types of particulates that are a potential health hazard. Particulates larger than microvessels may cause an embolism by mechanical blockage and inflammation;...

    Authors: Hajime Arima, Hiroyuki Hirate, Takeshi Sugiura, Shugo Suzuki, Satoru Takahashi and Kazuya Sobue
    Citation: Journal of Intensive Care 2014 2:21
  16. Yamakagashi (Rhabdophis tigrinus) is a species of pit viper present throughout Russia and Eastern Asia. Although R. tigrinus venom is known to induce life-threatening hemorrhagic symptoms, the clinical characteri...

    Authors: Toru Hifumi, Atsushi Sakai, Akihiko Yamamoto, Masahiro Murakawa, Manabu Ato, Keigo Shibayama, Akihiko Ginnaga, Hiroshi Kato, Yuichi Koido, Junichi Inoue, Yuko Abe, Kenya Kawakita, Masanobu Hagiike and Yasuhiro Kuroda
    Citation: Journal of Intensive Care 2014 2:19
  17. We tested the utility of the McGrath MAC® (McG) video laryngoscope during chest compression compared with the Pentax Airwayscope® (AWS). We recruited 59 participants into the simulation study. The difference in t...

    Authors: Atsushi Kotera, Hiroki Irie, Shinsuke Iwashita, Junichi Taniguchi, Shunji Kasaoka and Yoshihiro Kinoshita
    Citation: Journal of Intensive Care 2014 2:18
  18. Tracheotomy is an indispensable component in intensive care management. Doctors in charge of the intensive care unit (ICU) usually decide whether tracheotomy should be performed. However, long-term follow-up o...

    Authors: Yukihiro Ikegami, Ken Iseki, Chiaki Nemoto, Yasuhiko Tsukada, Jiro Shimada and Choichiro Tase
    Citation: Journal of Intensive Care 2014 2:17
  19. Supplemental landiolol administration (20 or 40 μg kg-1 min-1) effectively diminished harmful hemodynamic changes during bronchoscopic endotracheal suctioning compared to normal saline. However, inappropriate use...

    Authors: Toru Hifumi, Hiroshi Kato, Yuichi Koido, Kenya Kawakita and Yasuhiro Kuroda
    Citation: Journal of Intensive Care 2014 2:16
  20. Disseminated intravascular coagulation (DIC) is categorized into bleeding, organ failure, massive bleeding, and non-symptomatic types according to the sum of vectors for hypercoagulation and hyperfibrinolysis....

    Authors: Hideo Wada, Takeshi Matsumoto and Yoshiki Yamashita
    Citation: Journal of Intensive Care 2014 2:15
  21. Body temperature abnormalities, which occur because of several infectious and non-infectious etiologies, are among the most commonly noted symptoms of critically ill patients. These abnormalities frequently tr...

    Authors: Shigeki Kushimoto, Satoshi Yamanouchi, Tomoyuki Endo, Takeaki Sato, Ryosuke Nomura, Motoo Fujita, Daisuke Kudo, Taku Omura, Noriko Miyagawa and Tetsuya Sato
    Citation: Journal of Intensive Care 2014 2:14
  22. Here, we report a case of a 41-year-old male diagnosed as septic shock with purpura fulminans (PF) infection. The causative organism was β-lactamase-negative ampicillin-resistant Hemophilus influenzae. He develop...

    Authors: Akira Endo, Atsushi Shiraishi, Junichi Aiboshi, Yoshiro Hayashi and Yasuhiro Otomo
    Citation: Journal of Intensive Care 2014 2:13
  23. Active cytomegalovirus infection is not uncommon in critically ill non-immunosuppressed patients. We conducted a preliminary observational study to determine the prevalence of active cytomegalovirus infection ...

    Authors: Haruhiko Ishioka, Masamitsu Sanui, Yusuke Tsutsumi, Fumitaka Yanase and Junji Shiotsuka
    Citation: Journal of Intensive Care 2014 2:12
  24. Hypothermia and acidosis are secondary causes of trauma-related coagulopathy. Here we report the case of a 72-year-old patient with severe trauma who suffered near-severe hypothermia despite the initiation of ...

    Authors: Kazutaka Kiridume, Toru Hifumi, Kenya Kawakita, Tomoya Okazaki, Hideyuki Hamaya, Natsuyo Shinohara, Yuko Abe, Koshiro Takano, Masanobu Hagiike and Yasuhiro Kuroda
    Citation: Journal of Intensive Care 2014 2:11
  25. In Japan, the continuation of critical care at the end of life is a common practice due to the threat of legal action against physicians that may choose a palliative care approach. This is beginning to change ...

    Authors: Jun Makino, Shigeki Fujitani, Bridget Twohig, Steven Krasnica and John Oropello
    Citation: Journal of Intensive Care 2014 2:9
  26. The aim of the study was to understand the current status of intensive care unit (ICU) in order to optimize the resources achieving the best possible care.

    Authors: Kuo-Chen Cheng, Chin-Li Lu, Yueh-Chih Chung, Mei-Chen Huang, Hsiu-Nien Shen, Hsing-Min Chen and Haibo Zhang
    Citation: Journal of Intensive Care 2014 2:8
  27. The editors of Journal of Intensive Care would like to thank all our reviewers who have contributed to the journal in Volume 1 (2013).

    Authors: Satoshi Gando
    Citation: Journal of Intensive Care 2014 2:4
  28. During mechanical ventilation, endotracheal tube cuff pressure should be maintained within proper range. We investigated the effect of frequent adjustment on cuff pressure in 27 mechanically ventilated patient...

    Authors: Asuka Motoyama, Shota Asai, Hiroyuki Konami, Yuri Matsumoto, Takuyo Misumi, Hideaki Imanaka and Masaji Nishimura
    Citation: Journal of Intensive Care 2014 2:7
  29. Landiolol is an ultra-short-acting β1-selective antagonist developed in Japan that was recently approved for the treatment of tachycardia in intensive care units (ICUs). This study investigated the protective eff...

    Authors: Junpei Tochikubo, Yushi U Adachi, Tadashi Ejima, Atsushi Numaguchi, Naoyuki Matsuda, Shigehito Sato and Norihiko Shiiya
    Citation: Journal of Intensive Care 2014 2:6
  30. It remains to be clarified if the application of noninvasive positive pressure ventilation (NPPV) is effective after extubation in patients with hypoxemic respiratory failure who require the sufficient level o...

    Authors: Takeshi Suzuki, Takuya Kurazumi, Shinya Toyonaga, Yuya Masuda, Yoshihisa Morita, Junichi Masuda, Shizuko Kosugi, Nobuyuki Katori and Hiroshi Morisaki
    Citation: Journal of Intensive Care 2014 2:5
  31. Postoperative atelectasis should be avoided in surgical patients with impaired pulmonary function. Nasal high-flow (NHF) therapy delivered by the Optiflow™ system (Fisher & Paykel Healthcare Ltd., Auckland, Ne...

    Authors: Yasuyuki Suzuki and Yasushi Takasaki
    Citation: Journal of Intensive Care 2014 2:3
  32. Acute respiratory distress syndrome (ARDS) is characterized by permeability pulmonary edema and refractory hypoxemia. Recently, the new definition of ARDS has been published, and this definition suggested seve...

    Authors: Younsuck Koh
    Citation: Journal of Intensive Care 2014 2:2
  33. The Glasgow Coma Scale (GCS) score of an individual with hypoglycemia is expected to be low due to an insufficient glucose supply to the brain. However, we sometimes encounter hypoglycemic patients with high G...

    Authors: Atsushi Kotera, Shinsuke Iwashita, Hiroki Irie, Junichi Taniguchi, Shunji Kasaoka and Yoshihiro Kinoshita
    Citation: Journal of Intensive Care 2014 2:1
  34. Sepsis is a major risk factor for the development of thrombocytopenia, but few studies have specifically evaluated prognostic importance of thrombocytopenia in patients with sepsis. We investigated the inciden...

    Authors: Chakradhar Venkata, Rahul Kashyap, J Christopher Farmer and Bekele Afessa
    Citation: Journal of Intensive Care 2013 1:9
  35. Dexmedetomidine is a highly selective central α2-agonist with anesthetic and analgesic properties for patients in intensive care units. There is little information about the relationship between dosage and plasma...

    Authors: Yoshihito Fujita, Koichi Inoue, Tasuku Sakamoto, Saya Yoshizawa, Maiko Tomita, Yoshie Maeda, Hitomi Taka, Ai Muramatsu, Youichiro Hattori, Hiroyuki Hirate, Toshimasa Toyo'oka and Kazuya Sobue
    Citation: Journal of Intensive Care 2013 1:15
  36. Limited studies are available on prevalence and severity of vitamin D deficiency in a critically ill population. To the best of our knowledge, this the first study of its kind in an Indian intensive care set-up.

    Authors: Afzal Azim, Armin Ahmed, Subhash Yadav, Arvind K Baronia, Mohan Gurjar, Madan M Godbole, Banani Poddar and Ratender K Singh
    Citation: Journal of Intensive Care 2013 1:14
  37. Epinephrine administration has been advocated for cardiopulmonary resuscitation (CPR) for decades. Despite the fact that epinephrine administration during CPR is internationally accepted, the effects of the pr...

    Authors: Mineji Hayakawa, Satoshi Gando, Hirotoshi Mizuno, Yasufumi Asai, Yasuo Shichinohe, Isao Takahashi and Hiroshi Makise
    Citation: Journal of Intensive Care 2013 1:12
  38. In patients with severe sepsis, depression of cardiac performance is common and is often associated with left ventricular (LV) dilatation to maintain stroke volume. Although it is essential to optimize cardiac...

    Authors: Tomoyuki Endo, Shigeki Kushimoto, Satoshi Yamanouchi, Teruo Sakamoto, Hiroyasu Ishikura, Yasuhide Kitazawa, Yasuhiko Taira, Kazuo Okuchi, Takashi Tagami, Akihiro Watanabe, Junko Yamaguchi, Kazuhide Yoshikawa, Manabu Sugita, Yoichi Kase, Takashi Kanemura, Hiroyuki Takahashi…
    Citation: Journal of Intensive Care 2013 1:11
  39. Methicillin-resistant Staphylococcus aureus is still a great concern, and recognition of the carrier is essential for appropriate infection control in intensive care units. The utility of wet swab compared to dry...

    Authors: Hideharu Hagiya, Mitsunobu Mio, Tomoko Murase, Keiko Egawa, Yumi Kokumai, Taeko Uchida, Naoki Morimoto, Fumio Otsuka and Sumiko Shiota
    Citation: Journal of Intensive Care 2013 1:10
  40. Subcutaneous emphysema is not a rare complication in intensive care unit patients. Recently, ultrasound guidance for central venous puncture is becoming popular; however, the information on imaging for subcuta...

    Authors: Toshi Kubodera, Yushi U Adachi, Toshiyuki Hatano, Tadashi Ejima, Atsushi Numaguchi and Naoyuki Matsuda
    Citation: Journal of Intensive Care 2013 1:8
  41. Strongyloidiasis is a parasitic infection that occurs in tropical regions. Hyperinfection, which is an accelerated autoinfection, is often associated with an immunosuppressive state, such as HTLV-1 infection o...

    Authors: Yoshiaki Iwashita, Kei Suzuki, Asami Masui, Eiji Kawamoto, Kazuto Yokoyama, Akitaka Yamamoto, Yukinari Omori, Ken Ishikura, Tsuyoshi Hatada, Masaki Fujioka, Taichi Takeda and Hiroshi Imai
    Citation: Journal of Intensive Care 2013 1:7
  42. Although heated humidifiers (HHs) are the most efficient humidifying device for mechanical ventilation, some HHs do not provide sufficient humidification when the inlet temperature to the water chamber is high...

    Authors: Yusuke Chikata, Mutsuo Onodera, Hideaki Imanaka and Masaji Nishimura
    Citation: Journal of Intensive Care 2013 1:6

    The Erratum to this article has been published in Journal of Intensive Care 2013 1:16

  43. The Fundamental Critical Care Support (FCCS) course has been introduced after minimal adaptation according to Japanese clinical settings. The original course in the USA is often used to prepare residents for r...

    Authors: Kazuaki Atagi, Shinichi Nishi, Shigeki Fujitani, Takamitsu Kodama, Junya Ishikawa and Hideki Shimaoka
    Citation: Journal of Intensive Care 2013 1:5