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  1. Use of high-dose norepinephrine is thought to have an immunosuppressive action that increases mortality. This study aimed to evaluate the correlation between norepinephrine dosage and prognosis of patients wit...

    Authors: Hitoshi Yamamura, Yu Kawazoe, Kyohei Miyamoto, Tomonori Yamamoto, Yoshinori Ohta and Takeshi Morimoto
    Citation: Journal of Intensive Care 2018 6:12
  2. Acute respiratory distress syndrome (ARDS) is associated with high mortality rates. ARDS patients suffer from severe hypoxemia, and extracorporeal membrane oxygenation (ECMO) therapy may be necessary to ensure...

    Authors: Stefanie Prohaska, Andrea Schirner, Albina Bashota, Andreas Körner, Gunnar Blumenstock and Helene A. Haeberle
    Citation: Journal of Intensive Care 2018 6:11
  3. There are numerous barriers to early mobilization (EM) in a resource-limited intensive care unit (ICU) without a specialized team or an EM culture, regarding patient stability while critically ill or in the pr...

    Authors: Keibun Liu, Takayuki Ogura, Kunihiko Takahashi, Mitsunobu Nakamura, Hiroaki Ohtake, Kenji Fujiduka, Emi Abe, Hitoshi Oosaki, Dai Miyazaki, Hiroyuki Suzuki, Mitsuaki Nishikimi, Alan Kawarai Lefor and Takashi Mato
    Citation: Journal of Intensive Care 2018 6:10
  4. Sepsis is a global threat but insufficiently studied in Southeast Asia. The objective was to evaluate management, outcomes, adherence to sepsis bundles, and mortality prediction of maximum Sequential Organ Fai...

    Authors: Khie Chen Lie, Chuen-Yen Lau, Nguyen Van Vinh Chau, T. Eoin West and Direk Limmathurotsakul
    Citation: Journal of Intensive Care 2018 6:9
  5. Almost all data on 5-year outcomes for critical care survivors come from North America and Europe. The aim of this study was to investigate long-term mortality, physical function, psychological outcomes and he...

    Authors: Kimberley J. Haines, Sue Berney, Stephen Warrillow and Linda Denehy
    Citation: Journal of Intensive Care 2018 6:8
  6. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by th...

    Authors: Osamu Nishida, Hiroshi Ogura, Moritoki Egi, Seitaro Fujishima, Yoshiro Hayashi, Toshiaki Iba, Hitoshi Imaizumi, Shigeaki Inoue, Yasuyuki Kakihana, Joji Kotani, Shigeki Kushimoto, Yoshiki Masuda, Naoyuki Matsuda, Asako Matsushima, Taka-aki Nakada, Satoshi Nakagawa…
    Citation: Journal of Intensive Care 2018 6:7
  7. Weaning failure is a crucial hindrance in critically ill patients. Rapid shallow breathing index (RSBI), a well-known weaning index, has some limitations in predicting weaning outcomes. A new weaning index usi...

    Authors: Pattarin Pirompanich and Sasithon Romsaiyut
    Citation: Journal of Intensive Care 2018 6:6

    The Correction to this article has been published in Journal of Intensive Care 2018 6:25

  8. Outcomes for patients with ST-segment elevation myocardial infarction continue to improve, largely due to timely provision of reperfusion by primary percutaneous coronary intervention (PPCI). However, despite ...

    Authors: Ken Parhar, Victoria Millar, Vasileios Zochios, Emilia Bruton, Catherine Jaworksi, Nick West and Alain Vuylsteke
    Citation: Journal of Intensive Care 2018 6:5

    The Correction to this article has been published in Journal of Intensive Care 2018 6:32

  9. Despite a supportive evidence base and a push to implement, the uptake of early rehabilitation in critical care has been inconsistent. The objective of this study was to explore barriers and facilitators to ea...

    Authors: Shannon L. Goddard, Fabiana Lorencatto, Ellen Koo, Louise Rose, Eddy Fan, Michelle E. Kho, Dale M. Needham, Gordon D. Rubenfeld, Jill J. Francis and Brian H. Cuthbertson
    Citation: Journal of Intensive Care 2018 6:4
  10. Many intensive care unit (ICU) survivors develop psychological problems and cognitive impairment. The relation between sepsis, delirium, and later cognitive problems is not fully elucidated, and the impact of ...

    Authors: Emily Brück, Anna Schandl, Matteo Bottai and Peter Sackey
    Citation: Journal of Intensive Care 2018 6:2
  11. Stroke patients requiring decompressive craniectomy are at high risk of prolonged mechanical ventilation and ventilator-associated pneumonia (VAP). Tracheostomy placement may reduce the duration of mechanical ...

    Authors: Michael P. Catalino, Feng-Chang Lin, Nathan Davis, Keith Anderson, Casey Olm-Shipman and J. Dedrick Jordan
    Citation: Journal of Intensive Care 2018 6:1
  12. Patients in the ICU are often treated under extreme conditions, with the patient often fearful of losing his life or experiencing severe pain. As a result, high-quality pain management is required. However, re...

    Authors: Ryuichi Hasegawa
    Citation: Journal of Intensive Care 2017 5:73

    The original article was published in Journal of Intensive Care 2017 5:17

  13. During cardiopulmonary resuscitation (CPR), chest tubes can hinder increases in intrathoracic pressure by venting the pressure during chest compressions, thus reducing the blood flow generated by the thoracic ...

    Authors: Gu Hyun Kang, Hyun Youk, Kyoung Chul Cha, Yoonsuk Lee, Hyung Il Kim, Yong Sung Cha, Oh Hyun Kim, Hyun Kim, Kang Hyun Lee and Sung Oh Hwang
    Citation: Journal of Intensive Care 2017 5:71
  14. Lithium poisoning could trigger multiple complications. We report the case of a lithium poisoning with five complications that are described for the first time together.

    Authors: Jeremy Zaworski, Pierre-Yves Delannoy, Nicolas Boussekey, Damien Thellier, Hugues Georges and Olivier Leroy
    Citation: Journal of Intensive Care 2017 5:70
  15. Ventilator-associated respiratory infection (VARI) is a significant problem in resource-restricted intensive care units (ICUs), but differences in casemix and etiology means VARI in resource-restricted ICUs ma...

    Authors: Vu Dinh Phu, Behzad Nadjm, Nguyen Hoang Anh Duy, Dao Xuan Co, Nguyen Thi Hoang Mai, Dao Tuyet Trinh, James Campbell, Dong Phu Khiem, Tran Ngoc Quang, Huynh Thi Loan, Ha Son Binh, Quynh-Dao Dinh, Duong Bich Thuy, Huong Nguyen Phu Lan, Nguyen Hong Ha, Ana Bonell…
    Citation: Journal of Intensive Care 2017 5:69
  16. In a letter to the editor, Raineri SM et al. have given an insight of another dimension of procalcitonin (PCT) use as a diagnostic tool in invasive candidiasis. But based on our preliminary information, PCT is...

    Authors: R. Saikant, Shilpa Ravindran, Ashitha Vijayan, Vani Maya, S. Lakshmi, R. Kartik and Manoj G.
    Citation: Journal of Intensive Care 2017 5:68

    The original article was published in Journal of Intensive Care 2017 5:58

  17. The purpose of the work was to assess the contribution to diagnosis and/or treatment (CDT) of bone marrow aspiration (BMA) in the critically ill patient.

    Authors: Laure Calvet, Bruno Pereira, Anne-Françoise Sapin, Gabrielle Mareynat, Alexandre Lautrette and Bertrand Souweine
    Citation: Journal of Intensive Care 2017 5:67
  18. Maximal inspiratory pressure (MIP) is used to assess respiratory muscle strength of patients with myasthenia gravis (MG) requiring ventilatory support. Electrical activity of the diaphragm (E-di) has been used...

    Authors: Yukiko Koyama, Takeshi Yoshida, Akinori Uchiyama and Yuji Fujino
    Citation: Journal of Intensive Care 2017 5:66
  19. Dobutamine is commonly used worldwide and included in the protocol for early goal-directed therapy (EGDT). Since the use of dobutamine in EGDT was reported, it has been considered to be an important component,...

    Authors: Ryota Sato and Michitaka Nasu
    Citation: Journal of Intensive Care 2017 5:65
  20. Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness.

    Authors: Ryan R. Kroll, Erica D. McKenzie, J. Gordon Boyd, Prameet Sheth, Daniel Howes, Michael Wood and David M. Maslove
    Citation: Journal of Intensive Care 2017 5:64
  21. Diaphragm ultrasound (DUS) is a well-established point of care modality for assessment of dimensional and functional aspects of the diaphragm. Amongst various measures, diaphragmatic thickening fraction (DTf) is ...

    Authors: Sujay Samanta, Ratender Kumar Singh, Arvind K. Baronia, Banani Poddar, Afzal Azim and Mohan Gurjar
    Citation: Journal of Intensive Care 2017 5:62
  22. Central venous oxygen saturation (ScvO2) reflects the balance of oxygen delivery and consumption. Low ScvO2 indicates the presence of inadequate oxygen delivery, while high ScvO2 indicates reduced oxygen consumpt...

    Authors: Genri Numata, Satoshi Kodera, Hiroyuki Kiriyama, Atsuko Nakayama, Eisuke Amiya, Arihiro Kiyosue, Masaru Hatano, Eiki Takimoto, Masafumi Watanabe and Issei Komuro
    Citation: Journal of Intensive Care 2017 5:61
  23. Postoperative atrial fibrillation (AF) commonly occurs in cardiac surgery patients. Studies suggest inflammation and oxidative stress contribute to postoperative AF development in this patient population. Metf...

    Authors: Suresh Basnet, Andrzej Kozikowski, Haiyan Sun, Melissa Troup, Luis E. Urrutia and Renee Pekmezaris
    Citation: Journal of Intensive Care 2017 5:60
  24. Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surr...

    Authors: Santi Maurizio Raineri, Andrea Cortegiani, Filippo Vitale, Pasquale Iozzo and Antonino Giarratano
    Citation: Journal of Intensive Care 2017 5:58

    The Letter to the Editor to this article has been published in Journal of Intensive Care 2017 5:68

  25. Abdominal X-rays, the diagnostic method for enteral feeding tube (EFT) positioning, are a source of irradiation for the patients and carry a potential risk of adverse effects. Data related to ultrasound (US)-g...

    Authors: Wagner Luis Nedel, Mariana Nunes Ferreira Jost and João Wilney Franco Filho
    Citation: Journal of Intensive Care 2017 5:55
  26. Nonconvulsive status epilepticus (NCSE) is a diagnosis that is often challenging and one that may progress to refractory NCSE. Ketamine is a noncompetitive N-methyl-d-aspartate antagonist that increasingly has be...

    Authors: Michael A. Pizzi, Prasuna Kamireddi, William O. Tatum, Jerry J. Shih, Daniel A. Jackson and William D. Freeman
    Citation: Journal of Intensive Care 2017 5:54
  27. Interruption of enteral nutrition (EN) in the intensive care unit (ICU) occurs frequently for various reasons including feeding intolerance and the conduct of diagnostic and therapeutic procedures. However, fe...

    Authors: Midori Uozumi, Masamitsu Sanui, Tetsuya Komuro, Yusuke Iizuka, Tadashi Kamio, Hiroshi Koyama, Hideyuki Mouri, Tomoyuki Masuyama, Kazuyuki Ono and Alan Kawarai Lefor
    Citation: Journal of Intensive Care 2017 5:52
  28. Sepsis is a global healthcare problem, characterized by whole body inflammation in response to microbial infection, which leads to organ dysfunction. It is becoming a frequent complication in hospitalized pati...

    Authors: Ashitha L. Vijayan, Vanimaya, Shilpa Ravindran, R. Saikant, S. Lakshmi, R. Kartik and Manoj. G
    Citation: Journal of Intensive Care 2017 5:51
  29. The Japanese Society of Respiratory Care Medicine and the Japanese Society of Intensive Care Medicine provide here a clinical practice guideline for the management of adult patients with ARDS in the ICU.

    Authors: Satoru Hashimoto, Masamitsu Sanui, Moritoki Egi, Shinichiro Ohshimo, Junji Shiotsuka, Ryutaro Seo, Ryoma Tanaka, Yu Tanaka, Yasuhiro Norisue, Yoshiro Hayashi and Eishu Nango
    Citation: Journal of Intensive Care 2017 5:50
  30. Acute kidney injury (AKI) after cardiac surgery in children with congenital heart disease is a common complication. AKI is also associated with high morbidity and mortality. The Kidney Diseases Improving Globa...

    Authors: Yuichiro Toda and Kentaro Sugimoto
    Citation: Journal of Intensive Care 2017 5:49
  31. Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50–60 brain-dead donor organ transplants performed annually in Japan, ...

    Authors: Nao Nishimura, Mureo Kasahara, Kenji Ishikura and Satoshi Nakagawa
    Citation: Journal of Intensive Care 2017 5:48
  32. Sepsis is one of the leading causes of mortality among children worldwide. Unfortunately, however, reliable evidence was insufficient in pediatric sepsis and many aspects in clinical practice actually depend o...

    Authors: Tatsuya Kawasaki
    Citation: Journal of Intensive Care 2017 5:47
  33. In Japan, nafamostat mesylate (NM) is frequently used as an anticoagulant during continuous renal replacement therapy (CRRT). The dialyzer membrane AN69ST has been reported to adsorb NM and affect the manageme...

    Authors: Takahiro Hirayama, Nobuyuki Nosaka, Yasumasa Okawa, Soichiro Ushio, Yoshihisa Kitamura, Toshiaki Sendo, Toyomu Ugawa and Atsunori Nakao
    Citation: Journal of Intensive Care 2017 5:46
  34. Sepsis is a prevalent disease worldwide and still exhibits high rates of mortality. In the last years, many interventions aiming a positive impact on sepsis evolution have been studied. One of the main is the ...

    Authors: F. Teles, W. G. Rodrigues, M. G. T. C. Alves, C. F. T. Albuquerque, S. M. O. Bastos, M. F. A. Mota, E. S. Mota and F. J. L. Silva
    Citation: Journal of Intensive Care 2017 5:45
  35. The perfusion of splanchnic organs is deeply altered in patients with septic shock. The aim of the study is to identify the predictive factors of septic shock-induced increase of serum lipase and amylase and t...

    Authors: Anis Chaari, Karim Abdel Hakim, Nevine Rashed, Kamel Bousselmi, Vipin Kauts, Mahmoud Etman and William Francis Casey
    Citation: Journal of Intensive Care 2017 5:44
  36. Patients with severe sepsis generally respond well to initial therapy administered in the emergency department (ED), but a subset later decompensate and require unexpected transfer to the intensive care unit (...

    Authors: Gabriel Wardi, Arvin R. Wali, Julian Villar, Vaishal Tolia, Christian Tomaszewski, Christian Sloane, Peter Fedullo, Jeremy R. Beitler, Matthew Nolan, Daniel Lasoff and Rebecca E. Sell
    Citation: Journal of Intensive Care 2017 5:43
  37. Sepsis is one of the most significant causes of mortality in intensive care units. It indicates crosstalk between inflammation and coagulation. In this study, we aimed to identify prognostic markers among seps...

    Authors: Kota Hoshino, Taisuke Kitamura, Yoshihiko Nakamura, Yuhei Irie, Norihiko Matsumoto, Yasumasa Kawano and Hiroyasu Ishikura
    Citation: Journal of Intensive Care 2017 5:42
  38. The intensive care unit (ICU) environment exposes patients to noise levels that may result in substantial sleep disruption. There is a need to accurately describe the intensity pattern and source of noise in t...

    Authors: Lori J. Delaney, Marian J. Currie, Hsin-Chia Carol Huang, Violeta Lopez, Edward Litton and Frank Van Haren
    Citation: Journal of Intensive Care 2017 5:41
  39. The efficacy of polymyxin B-immobilized (PMX) fiber column on septic shock is still under debate. Recently, the result from “Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized controlled trial of ...

    Authors: Toshiaki Iba and Lucy Fowler
    Citation: Journal of Intensive Care 2017 5:40
  40. Extracorporeal membrane oxygenation (ECMO) have become more frequently used in daily ICU practice, heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication while on extracorporeal mem...

    Authors: Alain Rougé, Felix Pelen, Michel Durand and Carole Schwebel
    Citation: Journal of Intensive Care 2017 5:39
  41. Decannulation is an essential step towards liberating tracheostomized patients from mechanical ventilation. However, despite its perceived importance, there is no universally accepted protocol for this vital t...

    Authors: Ratender Kumar Singh, Sai Saran and Arvind K. Baronia
    Citation: Journal of Intensive Care 2017 5:38
  42. Patients with water intoxication may develop rhabdomyolysis. Existing studies suggest a relationship between the serum sodium correction rate and rhabdomyolysis. The aim of the present study was to determine t...

    Authors: Masahiro Kashiura, Kazuhiro Sugiyama and Yuichi Hamabe
    Citation: Journal of Intensive Care 2017 5:37
  43. Swift and adequate fluid loading is a cornerstone of septic shock therapy. Yet, careful assessment of volume responsiveness and volume amount during the resuscitation process is a prerequisite. Both overzealou...

    Authors: Patrick M. Honore and Herbert D. Spapen
    Citation: Journal of Intensive Care 2017 5:36