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Table 1 Baseline characteristics of each admission

From: Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study

Characteristics

No limitation

(n = 7991)

Withholding

(n = 1181)

Withdrawal

(n = 551)

P value

Demographics, n (%)

    

Age, mean ± SD

61.6 ± 14.9

69.1 ± 13.7

67.0 ± 14.1

 < 0.001

Female sex

2881 (36.1)

446 (37.8)

203 (36.8)

0.503

Race*

   

0.048

 Chinese

5392 (67.6)

842 (71.5)

375 (68.2)

 

 Malay

1206 (15.1)

172 (14.6)

79 (14.4)

 

 Indian

728 (9.1)

99 (8.4)

50 (9.1)

 

 Others

653 (8.2)

65 (5.5)

46 (8.4)

 

Religion

   

0.069

 Buddhism

2589 (32.4)

389 (32.9)

169 (30.7)

 

 Christianity

876 (11)

153 (13)

50 (9.1)

 

 Hinduism

377 (4.7)

61 (5.2)

31 (5.6)

 

 Islam

1338 (16.7)

195 (16.5)

80 (14.5)

 

 Sikhism

39 (0.5)

5 (0.4)

3 (0.5)

 

 Taoism

242 (3)

44 (3.7)

26 (4.7)

 

 Others

74 (0.9)

8 (0.7)

3 (0.5)

 

 None stated

2456 (30.7)

326 (27.6)

189 (34.3)

 

Severe comorbidities, n (%)

    

 Chronic kidney dialysis

638 (8)

127 (10.8)

49 (8.9)

0.005

 Malignancya

419 (5.2)

123 (10.4)

41 (7.4)

 < 0.001

 Immunocompromisedb

417 (5.2)

105 (8.9)

40 (7.3)

 < 0.001

 Chronic liver failurec

215 (2.7)

68 (5.8)

17 (3.1)

 < 0.001

 Severe cardiovascular diseased

113 (1.4)

39 (3.3)

12 (2.2)

 < 0.001

 Severe respiratory diseasee

80 (1)

25 (2.1)

10 (1.8)

0.002

Activities of daily livingf, n (%)

   

 < 0.001

 Independent

7021 (87.9)

907 (76.8)

433 (78.6)

 

 Partially dependent

724 (9.1)

190 (16.1)

87 (15.8)

 

 Totally dependent

246 (3.1)

84 (7.1)

31 (5.6)

 

 CPR 24 h before ICU admission, n (%)

374 (4.7)

270 (22.9)

170 (30.9)

 < 0.001

 APACHE II score, mean ± SD

17.5 ± 7.4

27.2 ± 9

25.6 ± 8.1

 < 0.001

Hospital paying class, n (%)

   

0.001

 A and B1g

855 (10.7)

103 (8.7)

34 (6.2)

 

 B2 and Ch

7136 (89.3)

1078 (91.3)

517 (93.8)

 
  1. SD standard deviation, CPR cardiopulmonary resuscitation, ICU intensive care unit, APACHE Acute Physiology and Chronic Health Evaluation
  2. Given the aim of comparing characteristics associated with withholding and withdrawal of life-sustaining treatments, each admission including readmissions is considered separately; thus, classification of withholding and withdrawal applies to orders specific to each admission
  3. a−hPlease see Additional file 1: Table S5 for the definition of these baseline characteristics
  4. *Data missing for 16 patients for race