Table 1 Baseline characteristics of ARDS patient cohorts with absolute standardized mean differences pre- and post-matching
Characteristic | Before PSM | After PSM | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|  | All patients (n = 1498) | Non-heparin (n = 502) | Early heparin users (n = 996) | P value | SMD | All patients (n = 1004) | Non-heparin (n = 502) | Early heparin users (n = 502) | P value | SMD |
Admission_age | 65.0 [55.0, 77.0] | 66.0 [56.0, 77.0] | 65.0 [54.0, 77.0] | 0.13 | 0.0861 | 66.0 [56.0, 77.0] | 66.0 [56.0, 77.0] | 65.0 [55.0, 78.0] | 0.756 | 0.0121 |
Gender (female) | 640 (42.72%) | 205 (40.84%) | 435 (43.67%) | 0.321 | 0.0284 | 420 (41.83%) | 205 (40.84%) | 215 (42.83%) | 0.565 | 0.0199 |
White | 1002 (66.89%) | 347 (69.12%) | 655 (65.76%) | 0.213 | 0.0336 | 694 (69.12%) | 347 (69.12%) | 347 (69.12%) | 1 | 0 |
Cancer | 234 (15.62%) | 86 (17.13%) | 148 (14.86%) | 0.286 | 0.0227 | 182 (18.13%) | 86 (17.13%) | 96 (19.12%) | 0.461 | 0.0199 |
Diabetes | 464 (30.97%) | 150 (29.88%) | 314 (31.53%) | 0.555 | 0.0165 | 317 (31.57%) | 150 (29.88%) | 167 (33.27%) | 0.277 | 0.0339 |
Sepsis | 154 (10.28%) | 57 (11.35%) | 97 (9.74%) | 0.378 | 0.0162 | 113 (11.25%) | 57 (11.35%) | 56 (11.16%) | 1 | 0.002 |
Copd | 175 (11.68%) | 51 (10.16%) | 124 (12.45%) | 0.223 | 0.0229 | 100 (9.96%) | 51 (10.16%) | 49 (9.76%) | 0.916 | 0.004 |
Hypertension | 491 (32.78%) | 138 (27.49%) | 353 (35.44%) | 0.002 | 0.0795 | 279 (27.79%) | 138 (27.49%) | 141 (28.09%) | 0.888 | 0.006 |
Acute_pancreatitis | 35 (2.34%) | 8 (1.59%) | 27 (2.71%) | 0.242 | 0.0112 | 16 (1.59%) | 8 (1.59%) | 8 (1.59%) | 1 | 0 |
Acute renal failure | 320 (21.36%) | 91 (18.13%) | 229 (22.99%) | 0.036 | 0.0486 | 185 (18.43%) | 91 (18.13%) | 94 (18.73%) | 0.871 | 0.006 |
Sofa | 6.0 [4.0, 9.0] | 7.0 [4.0, 10.0] | 6.0 [4.0, 8.0] |  < 0.001 | 0.2519 | 7.0 [4.0, 9.0] | 7.0 [4.0, 10.0] | 7.0 [5.0, 9.0] | 0.842 | 0.0336 |
Sapsii | 41.0 [33.0, 51.0] | 41.0 [34.0, 51.0] | 40.0 [32.0, 51.0] | 0.045 | 0.1142 | 42.0 [34.0, 52.0] | 41.0 [34.0, 51.0] | 42.0 [34.0, 52.0] | 0.982 | 0.0215 |
Oasis | 36.0 [31.0, 42.0] | 36.0 [31.0, 42.0] | 36.0 [31.0, 42.0] | 0.337 | 0.0473 | 36.0 [31.0, 42.0] | 36.0 [31.0, 42.0] | 36.0 [31.0, 42.0] | 0.575 | 0.0306 |
Heart_rate_mean | 87.38 [76.41, 99.36] | 84.81 [75.57, 97.53] | 88.91 [76.71, 100.08] | 0.015 | 0.1034 | 86.66 [75.75, 98.56] | 84.81 [75.57, 97.53] | 88.74 [75.97, 98.88] | 0.181 | 0.0468 |
mbp | 75.31 [70.0, 82.65] | 74.72 [69.53, 81.93] | 75.60 [70.11, 83.09] | 0.089 | 0.0679 | 74.59 [69.58, 81.90] | 74.72 [69.53, 81.93] | 74.56 [69.72, 81.88] | 0.92 | 0.0331 |
Resp_rate | 19.65 [17.27, 22.52] | 18.83 [16.74, 21.82] | 20.13 [17.61, 22.76] |  < 0.001 | 0.2077 | 19.11 [16.98, 21.92] | 18.83 [16.74, 21.82] | 19.39 [17.20, 22.02] | 0.106 | 0.0418 |
pao2fio2ratio | 130.0 [82.89, 194.21] | 136.67 [88.57, 206.5] | 125.0 [80.0, 189.25] | 0.01 | 0.146 | 136.67 [88.0, 208.08] | 136.67 [88.57, 206.5] | 136.67 [87.36, 209.64] | 0.921 | 0.0057 |
Vaso | 871 (58.14%) | 313 (62.35%) | 558 (56.02%) | 0.022 | 0.0633 | 623 (62.05%) | 313 (62.35%) | 310 (61.75%) | 0.897 | 0.006 |
Ventilation | 661 (44.13%) | 204 (40.64%) | 457 (45.88%) | 0.061 | 0.0525 | 416 (41.43%) | 204 (40.64%) | 212 (42.23%) | 0.654 | 0.0159 |
rrt | 171 (11.42%) | 75 (14.94%) | 96 (9.64%) | 0.003 | 0.053 | 148 (14.74%) | 75 (14.94%) | 73 (14.54%) | 0.929 | 0.004 |
crrt | 119 (7.94%) | 46 (9.16%) | 73 (7.33%) | 0.255 | 0.0183 | 98 (9.76%) | 46 (9.16%) | 52 (10.36%) | 0.595 | 0.012 |