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Table 1 Baseline characteristics of patients with COVID-19 pneumonia treated with high-flow nasal cannula

From: External validation of the HACOR score and ROX index for predicting treatment failure in patients with coronavirus disease 2019 pneumonia managed on high-flow nasal cannula therapy: a multicenter retrospective observational study in Japan

Characteristic

N

Overall, N = 300

Non-failure, N = 173

Failure, N = 127

Age, years

300

60 (51, 70)

60 (51, 69)

61 (50, 72)

Male

300

228 (76)

130 (75)

98 (77)

Body mass index, kg/m2

286

25.2 (22.6, 29.3)

25.0 (22.6, 28.6)

25.7 (22.8, 31.7)

Hypertension

300

146 (49)

83 (48)

63 (50)

Chronic pulmonary disease

300

28 (9.3)

11 (6.4)

17 (13)

Any tumor

300

20 (6.7)

8 (4.6)

12 (9.4)

Chronic heart failure

300

13 (4.3)

9 (5.2)

4 (3.1)

Diabetes

300

75 (25)

42 (24)

33 (26)

Dementia

300

9 (3.0)

7 (4.0)

2 (1.6)

Delirium

299

9 (3.0)

5 (2.9)

4 (3.2)

Vaccination, doses

276

   

 0

 

245 (89)

138 (87)

107 (91)

 1

 

6 (2.2)

4 (2.5)

2 (1.7)

 2

 

23 (8.3)

16 (10)

7 (6.0)

 3

 

2 (0.7)

1 (0.6)

1 (0.9)

SOFA score

282

2 (2, 3)

2 (2, 3)

2.00 (2.00, 3.00)

APACHE2

254

9 (6, 13)

9 (6, 13)

8 (6, 12)

Heart rate, bpm/min

284

82 (72, 92)

80 (71, 91)

84 (78, 99)

Glasgow come scale

291

15 (15, 15)

15(15, 15)

15 (15, 15)

Body temperature, °C

282

37.0 (36.6, 37.8)

36.8 (36.5, 37.6)

37.2 (36.7, 38.0)

Respiratory rate, bpm/min

278

25 (21, 30)

25 (20, 30)

25 (22, 30)

SpO2

295

92 (90., 95.)

93 (91, 96)

91 (88, 93)

FiO2

280

0.75 (0.50, 0.95)

0.60 (0.44, 0.95)

0.90 (0.60, 0.95)

SpO2/FiO2

280

121 (96, 184)

145 (100, 211)

101 (93, 158)

Number of days from onset to hospitalization

300

7 (5, 10)

8 (4, 10)

6 (5, 8)

Number of days from admission to HFNC

300

0.83 (0.62, 1.65)

0.83 (0.65, 1.56)

0.84 (0.60, 1.78)

Total bilirubin, mg/dL

295

0.56 (0.43, 0.70)

0.57 (0.49, 0.72)

0.51 (0.40, 0.70)

Blood urea nitrogen, mg/dL

295

19 (14, 26)

19 (13, 24)

21 (15, 28)

Creatinine, mg/dL

294

0.81 (0.66, 1.07)

0.78 (0.63, 0.95)

0.85 (0.70, 1.15)

Platelets, 103/µL

295

169 (108, 226)

179 (89, 246)

160 (116, 220)

  1. Data are shown as n (%) or median (interquartile range). APACHE: Acute Physiology and Chronic Health Evaluation; FiO2: fraction of inspired oxygen; SOFA: Sequential Organ Failure Assessment; SpO2: oxygen saturation