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Table 3 Survival, complications, and event-free days

From: The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma

Variable

RBC transfusion strategy

Restrictive (n = 216)

Liberal (n = 195)

28-day survival, n (%)

199 (92.1)

178 (91.3)

Complications during the first 7 days, n (%)

 Respiratory failure

23 (10.6)

18 (9.2)

 Renal failure

7 (3.2)

11 (5.6)

 Hepatic failure

2 (0.9)

4 (2.1)

Complications during the first 28 days, n (%)

 Transfusion-related acute lung injury

0 (0.0)

0 (0.0)

 Cerebral infarction

5 (2.3)

2 (1.0)

 Pulmonary embolism

5 (2.3)

2 (1.0)

 Acute myocardial infarction

0 (0.0)

0 (0.0)

 Bowel ischemia

1 (0.5)

1 (0.5)

 Deep venous thrombosis

24 (11.1)

17 (8.7)

 Sepsis

5 (2.3)

13 (6.7)

Event-free days during the first 28 days, median (IQR)a

 ICU-free days

19.0 (12.0–24.0)

19.0 (8.0–24.0)

 Ventilator-free days

25.5 (18.0–28.0)

24.0 (18.0–27.0)

 Catecholamine-free days

28.0 (27.0–28.0)

28.0 (27.0–28.0)

  1. ICU Intensive Care Unit, IQR interquartile range, RBC red blood cell
  2. aData on event-free days were missing for one patient in the liberal RBC transfusion strategy group