Fig. 1

In-hospital mortality within 90 days after admission and organ dysfunction within 72 h after admission. a Regression lines of in-hospital mortality estimated by multivariable Cox proportional hazard regression model including the cross-product term between the DIC score and PT-INR value. In-hospital mortality increased with higher values of PT-INR, and this trend was more prominent with higher DIC scores. b Regression lines of the development of MODS estimated by multivariate logistic regression analysis. The odds of the development of MODS in patients with DIC increased with higher PT-INR values and DIC scores. c Regression lines of the SOFA scores at 72 h after admission estimated by a multivariable linear regression model. The SOFA score was higher with higher PT-INR values, and this trend was more prominent with higher DIC scores. Solid and dashed lines indicate the estimated log-transformed hazard, and shaded areas represent 95% confidence intervals. DIC, disseminated intravascular coagulation; PT-INR, prothrombin time-international normalized ratio; MODS, multiple organ dysfunction syndrome; SOFA, Sequential Organ Failure Assessment