Table 2 Clinical characteristics of patients with acute pancreatitis (ICU cohort)
Characteristics | Day 1 (Admission to ICU) | ||
|---|---|---|---|
Severe or necrotizing (n = 33) | Non-severe edematous (n = 26) | P value | |
Age (years) | 48 (38;61) | 69 (49;77) | 0.007 |
Male sex | 23 (70%) | 14 (54%) | 0.22 |
BMI (kg/m.2) | 27.0 (23.2;33.2) | 27.3 (24.6;29.3) | 0.91 |
Etiology | |||
Biliary Alcoholic Other | 10 (30%) 11 (33%) 12 (36%) | 7 (27%) 9 (35%) 10 (38%) | 0.73 |
Hemoglobin (g/dl) | 12.9 (10.5;15.1) | 13.4 (10.9;15.8) | 0.53 |
Hematocrit (%) | 37 (31;42) | 39 (33;47) | 0.26 |
INR | 1.1 (1.1;1.3) | 1.1 (1.0;1.3) | 0.67 |
PTT (s) Platelets (/nl) | 26.3 (24.1;31.3) 213 (144;278) | 29.0 (25.0;32.8) 213 (121;307) | 0.39 0.67 |
Ca2+ (mmol/l) | 1.99 (1.78;2.10) | 2.09 (1.93;2.24) | 0.80 |
LDH (U/l) | 312 (219;605) | 258 (201;405) | 0.15 |
Bilirubin (mg/dl) | 1.1 (0.7;2.6) | 0.85 (0.4;2.6) | 0.25 |
ALP (U/l) | 85 (58;129) | 100 (72;124) | 0.53 |
GGT (U/l) | 143 (77;304) | 222 (79;493) | 0.32 |
Amylase (U/l) | 554 (299;888) | 210 (93;1248) | 0.23 |
Lipase (U/l) | 506 (230;1509) | 968 (545;3388) | 0.13 |
ALT (U/l) | 64 (28;138) | 71 (29;231) | 0.46 |
AST (U/l) | 62 (31;128) | 67 (38;250) | 0.37 |
Albumin (g/l) | 28 (26;31) | 32 (27;37) | 0.09 |
Glucose (mg/dl) | 131 (102;181) | 124 (94;149) | 0.21 |
Creatinine (µmol/l) | 80 (52;107) | 106 (55;190) | 0.15 |
SOFA score | 5 (2.5;8.5) | 5 (0.25;8) | 0.56 |
SAPS II score | 25 (19;37) | 30 (20.5;39) | 0.42 |
APACHE II score | 16 (8;21) | 16 (8;24) | 0.90 |
Ranson 0 h (points) | 1 (1;2) | 1 (1;2) | 0.96 |
CRP (mg/l) | 142 (51;232) | 67 (22;163) | 0.06 |
PCT (ng/ml) | 0.9 (0.3;8.6) | 0.7 (0.2;3.0) | 0.47 |
WBC (/nl) | 13.3 (8.9;17.1) | 12.2 (7.55;18.5) | 0.69 |
sCD206 (mg/l) | 1.76 (1.43;2.82) | 1.25 (0.73;1.76) | 0.005 |
vWF:Ag (%) | 240 (186;464) | 184 (140;308) | 0.03 |
vWF:RCo (%) | 177 (87;339) | 129 (100;301) | 0.67 |