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Table 4 Subgroup analysis for hospital mortality by quartile of the timing of tracheostomy

From: Association between early tracheostomy and patient outcomes in critically ill patients on mechanical ventilation: a multicenter cohort study

 

Q1

Tracheostomy ≤ 6 days

Q2

Tracheostomy 7–10 days

Q3

Tracheostomy 11–14 days

Q4

Tracheostomy > 14 days

OR for quartile increment (95% CI)

p value for trend

p value for interaction*

Level of consciousness at ICU admission

      

0.310

GCS score < 8 (n = 498)

 n (%)

36/160 (22.5%)

32/161 (19.9%)

29/98 (29.6%)

24/79 (30.4%)

   

 Crude OR (95% CI)

1 (reference)

0.85 (0.5–1.46)

1.45 (0.82–2.56)

1.5 (0.82–2.76)

1.19 (0.98–1.44)

0.081

 

GCS ≥ 8 (n = 1040)

 n (%)

43/286 (15.0%)

71/244 (29.1%)

67/225 (29.8%)

94/285 (33.0%)

   

 Crude OR (95% CI)

1 (reference)

2.32 (1.51–3.55)

2.4 (1.56–3.69)

2.78 (1.85–4.18)

1.33 (1.18–1.51)

< 0.001

 

Diagnosis for ICU admission (respiratory failure)

      

0.218

Patients with respiratory failure (n = 834)

 n (%)

52/255 (20.4%)

74/238 (31.1%)

62/172 (36.0%)

56/169 (33.1%)

   

Crude OR (95% CI)

1 (reference)

1.76 (1.17–2.65)

2.2 (1.42–3.4)

1.93 (1.24–3.01)

1.25 (1.09–1.43)

0.001

 

Patients without respiratory failure (n = 704)

 n (%)

27/191 (14.1%)

29/167 (17.4%)

34/151 (22.5%)

62/195 (31.8%)

   

 Crude OR (95% CI)

1 (reference)

1.28 (0.72–2.26)

1.77 (1.01–3.08)

2.83 (1.71–4.7)

1.43 (1.21–1.67)

< 0.001

 

Diagnosis for ICU admission (cardiovascular surgery)

      

0.681

Patients after cardiovascular surgery (n = 202)

 n (%)

2/13 (15.4%)

5/32 (15.6%)

13/45 (28.9%)

35/112 (31.3%)

   

 Crude OR (95% CI)

1 (reference)

1.02 (0.17–6.11)

2.23 (0.43–11.5)

2.5 (0.53–11.9)

1.41 (0.98–2.03)

0.063

 

Other patients (n = 1336)

 n (%)

77/433 (17.8%)

98/373 (26.3%)

83/278 (29.9%)

83/252 (32.9%)

   

 Crude OR (95% CI)

1 (reference)

1.65 (1.18–2.31)

1.97 (1.38–2.81)

2.27 (1.58–3.26)

1.3 (1.17–1.46)

< 0.001

 
  1. *p value for interaction is calculated between the timing of the tracheostomy and the diagnosis for ICU admission
  2. OR odds ratio, CI confidence interval, ICU intensive care unit, GCS Glasgow Coma Scale
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Journal of Intensive Care

ISSN: 2052-0492