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Table 1 Patient’s demographic and clinical characteristics at T1

From: Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents

  All patients No significant Significant p value
FR-APG FR-APG
n (%) 81 66 (81) 15 (19)  
Gender, male/female, n 53/28 44/22 9/6 0.85
Age, year 68 [58, 75] 68 [58, 75] 70 [65, 76] 0.365
Height, cm 168 (10) 168 (10) 169 (11) 0.761
Weight, kg 80 [71, 94] 80 [71, 94] 81 [75, 87] 0.863
BMI, cm/kg2 29 (5) 29 (6) 29 (4) 0.848
Background     
 Hypertension 53 (66%) 41 (63%) 12 (80%) 0.344
 Diabetes melitus 23 (29%) 15 (23%) 8 (53%) 0.044
 Ischemic cardiomyopathy 41 (51%) 36 (55%) 5 (33%) 0.231
Clinical context     
 Cardiac surgery 68 57 (86%) 11(73%) 0.247
 Septic shock 5 4 (6%) 1 (7%) 0.904
 Other 8 5 (8%) 3 (20%) 0.162
Cardiac and metabolic function     
 LVEF, % 54 [40, 60] 52 [40, 60] 56 [49, 65] 0.144
 Lactate, mmol/L 1.95 [1.10, 2.70] 1.8 [1.0, 2.4] 2.8 [1.6, 5.2] 0.021
 Temperature, °C 36.7 (0.7) 36.7 (0.7) 36.9 (1.0) 0.511
 ScvO2, % 73 [68, 77] 73 [67, 77] 71 [70, 77] 0.76
 Mean NIRS, % 69 [69, 70] 70 [69, 70] 69 [68, 69] 0.14
Fluid     
 Fluid intake, mL 2472 [1833, 3189] 2475 [1805, 3275] 2315 [2113, 2600] 0.731
 Fluid loss, mL 1362 [593, 2401] 1398 [635, 2637] 1325 [527, 1715] 0.507
 Fluid balance, mL 1320 [612, 2014] 1300 [573, 1851] 1775 [934, 2619] 0.165
 Creatinine, µmol/L 105 [81, 138] 103 [80, 127] 121 [89, 168] 0.379
Severity scores     
 SAPS2 35 (7) 34 (7) 39 (10) 0.146
 SOFA score 6 [4, 7] 5 [4, 7] 6 [5, 8] 0.218
Drugs     
 Norepinephrine, µg/kg/min 0.16 [0.08, 0.28] 0.15 [0.08, 0.25] 0.30 [0.15, 0.50] 0.02
 Epinephrine, µg/kg/min 0.07 [0.04, 0.10] 0.05 [0.04, 0.08] 0.09 [0.07, 0.10] 0.294
 Vasopressine, ui/kg/min 2.40 [2.40, 2.40] 2.40 [2.40, 2.40] 2.40 [2.40, 2.40] 0.378
 Dobutamine, µg/kg/min 3.00 [2.50, 5.00] 2.50 [2.50, 3.75] 4.00 [3.50, 4.50] 0.361
 Milrinone, µg/kg/min 0.34 [0.25, 0.47] 0.31 [0.25, 0.41] 0.40 [0.35, 0.45] 0.411
Hemodynamic     
 HR, beat/min 78 (12) 77 (12) 83 (11) 0.249
Radial artery     
SAP, mmHg 103 (17) 107 (16) 89 (13)  < 0.001
DAP, mmHg 54 (10) 56 (9) 46 (10)  < 0.001
MAP, mmHg 69 (11) 72 (9) 58 (10)  < 0.001
Femoral artery     
SAP, mmHg 113(15) 110 (13) 125 (18)  < 0.001
DAP, mmHg 55 (9) 56 (8) 50 (8) 0.009
MAP, mmHg 72 [68, 78] 72[68, 78] 70 [64, 77] 0.315
  1. Variables are expressed as mean (standard deviation) or median [interquartile range] according to their distributions
  2. BMI body mass index; DAP diastolic arterial pressure; LVEF left ventricular ejection fraction; MAP mean arterial pressure; NIRS near-infrared spectroscopy; FR-APG femoral-to-radial arterial pressure gradient; HR heart rate; SAP systolic arterial pressure; SAPS2 Simplified Acute Physiology Score; ScVO2 central venous oxygenation saturation; SIRS systemic inflammatory response syndrome; SOFA Sequential Organ Failure Assessment