Table 4 Baseline characteristics of ARDS patients in different MLR levels
Variables | Low MLR (MLR < 0.90, n = 186) | High MLR (MLR ≥ 0.90, n = 82) | P value |
|---|---|---|---|
Age (years) | 67 (60.75–72) | 68 (62–73) | 0.448 |
Male, n (%) | 131 (70.4) | 61 (74.4) | 0.507 |
Smoking, n (%) | 61 (32.8) | 24 (29.3) | 0.567 |
Alcohol abuse, n (%) | 47 (25.3) | 16 (19.5) | 0.306 |
Hypertension, n (%) | 82 (44.1) | 34 (41.5) | 0.690 |
Diabetes mellitus, n (%) | 50 (26.9) | 24 (29.3) | 0.687 |
Coronary artery disease, n (%) | 39 (21) | 15 (18.3) | 0.615 |
Risk factor, n (%) | Â | Â | 0.263 |
 Pneumonia | 167 (89.7) | 79 (96.3) |  |
 Aspiration | 8 (4.3) | 2 (2.4) |  |
 Sepsis | 5 (2.8) | 1 (1.3) |  |
 Others | 6 (3.2) | 0 (0) |  |
Types of infection, n (%) | Â | Â | 0.629 |
 Bacteria | 138 (74.2) | 65 (79.3) |  |
 Virus | 7 (3.8) | 1 (1.2) |  |
 Fungus | 26 (14) | 11 (13.4) |  |
 Unknown | 15 (8) | 5 (6.1) |  |
PaO2/FiO2 (mmHg) | 142 (101–194) | 138 (87.61–184.25) | 0.386 |
Categories of ARDS, n (%) | Â | Â | 0.546 |
 Mild | 40 (21.5) | 17 (20.7) |  |
 Moderate | 101 (54.3) | 40 (48.8) |  |
 Severe | 45 (24.2) | 25 (30.5) |  |
WBC, 109/L | 9.56 (6.86–11.75) | 9.7 (6.67–11.89) | 0.944 |
Hemoglobin, g/L | 112.5 (98–129.25) | 105 (91.5–124.25) | 0.091 |
RDW, % | 13.75 (12.9–15.1) | 13.9 (13–14.9) | 0.775 |
Lactate, mmol/L | 2.2 (1.4–3.83) | 2.6 (1.5–3.73) | 0.192 |
Albumin, g/L | 32.9 (28.9–37.7) | 32.15 (28.58–37.3) | 0.349 |
MLR | 0.41 (0.26–0.59) | 1.49 (1.15–2.24) | <0.001 |
NLR | 8.45 (4.47–16.09) | 20.62 (13.11–35.12) | <0.001 |
RDW/albumin, %/g/L | 0.43 (0.36–0.51) | 0.43 (0.37–0.49) | 0.903 |
AST | 50.45 (21.03–139.13) | 75.25 (28.7–151.78) | 0.106 |
ALT | 54.55 (20–125.93) | 62.45 (25.28–149.53) | 0.465 |
Cr, μmol/L | 94.35 (58.28–181.88) | 134.7 (71.78–197.98) | 0.025 |
BUN, mmol/L | 13.28 (7.4–17.8) | 13.57 (9.79–19.2) | 0.154 |
APACHE II score | 12 (9–16) | 14 (10–17.25) | 0.308 |
SOFA score | 7 (6–9) | 8 (7–9) | 0.046 |
Interventions, n (%) | Â | Â | Â |
 Steroida | 129 (69.4) | 55 (67.1) | 0.711 |
 Hypoglycemic | 58 (31.2) | 23 (28) | 0.607 |
 Alimentotherapy | 113 (60.8) | 66 (80.5) | 0.002 |
 Albumin infusion | 82 (44.1) | 55 (67.1) | 0.001 |
 Transfusion | 51 (27.4) | 32 (39) | 0.058 |
 CRRT | 23 (12.4) | 16 (19.5) | 0.126 |
 ECMO | 7 (3.8) | 4 (4.9) | 0.672 |
 Mechanical ventilation | 109 (58.6) | 50 (61) | 0.715 |
28-day mortality, n (%) | 38 (20.4) | 47 (57.3) | <0.001 |
Duration of ventilation | 6 (2–12) | 10 (3.75–14) | 0.008 |
Hospital length of stay | 19 (12–24.25) | 18.5 (12.75–25) | 0.787 |