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Table 4 Subgroup and sensitivity analysis of the association between physical restraint and unfavorable (mRS3-6) outcome

From: Association between physical restraint requirement and unfavorable neurologic outcomes in subarachnoid hemorrhage

Models and variables Univariate analysis Multivariable analysis
OR (95% CI) p value OR (95% CI) p value
RASS ≥ − 2 (n = 82)
 Physical restraint during the first 24 to 72 h after admission
  No physical restraint Reference   Reference  
  Intermittent physical restraint 3.02 (0.97–9.82) 0.057 1.58 (0.40–6.16) 0.509
  Continuous physical restraint 8.29 (2.65–28.87) < 0.001 6.88 (1.69–32.36) 0.007
Hunt & Kosnik grades 1–3 (n = 81)
 Physical restraint during the first 24 to 72 h after admission
  No physical restraint Reference   Reference  
  Intermittent physical restraint 2.64 (0.87–8.25) 0.088 1.92 (0.50–7.44) 0.338
  Continuous physical restraint 7.25 (2.31–25.49) < 0.001 6.94 (1.66–33.92) 0.007
Different definition (continuous variable)
 Physical restraint during the first 24 to 72 h after admission (OR per each 5 h) 1.18 (1.07–1.30) 0.001 1.13 (1.01–1.28) 0.039
  1. Adjusted factors were the same as those during primary analysis: physical restraint requirement during the first 24 to 72 h after admission, age (> 65 years), Hunt & Kosnik grade, treatment modality (coil or clip), and aneurysm location (anterior cerebral arteries or not)
  2. mRS modified Rankin scale, OR Odds ratio, CI Confidence interval