Association between physical restraint requirement and unfavorable neurologic outcomes in subarachnoid hemorrhage

Table 4 Subgroup and sensitivity analysis of the association between physical restraint and unfavorable (mRS3-6) outcome

Models and variables	Univariate analysis		Multivariable analysis
Models and variables	OR (95% CI)	p value	OR (95% CI)	p value
RASS ≥ − 2 (n = 82)
Physical restraint during the first 24 to 72 h after admission
No physical restraint	Reference		Reference
Intermittent physical restraint	3.02 (0.97–9.82)	0.057	1.58 (0.40–6.16)	0.509
Continuous physical restraint	8.29 (2.65–28.87)	< 0.001	6.88 (1.69–32.36)	0.007
Hunt & Kosnik grades 1–3 (n = 81)
Physical restraint during the first 24 to 72 h after admission
No physical restraint	Reference		Reference
Intermittent physical restraint	2.64 (0.87–8.25)	0.088	1.92 (0.50–7.44)	0.338
Continuous physical restraint	7.25 (2.31–25.49)	< 0.001	6.94 (1.66–33.92)	0.007
Different definition (continuous variable)
Physical restraint during the first 24 to 72 h after admission (OR per each 5 h)	1.18 (1.07–1.30)	0.001	1.13 (1.01–1.28)	0.039

Adjusted factors were the same as those during primary analysis: physical restraint requirement during the first 24 to 72 h after admission, age (> 65 years), Hunt & Kosnik grade, treatment modality (coil or clip), and aneurysm location (anterior cerebral arteries or not)
mRS modified Rankin scale, OR Odds ratio, CI Confidence interval

ISSN: 2052-0492