Table 4 Meta-regression analysis
Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
Variables | Coeff | SE | 95% CI | P | Coeff | SE | 95% CI | P |
Sample size | 0.00 | 0.00 | − 0.01–0.01 | 0.55 | – | – | – | – |
Age (years) | 0.06 | 0.08 | − 0.09–0.22 | 0.40 | – | – | – | – |
Male gender (%) | 0.06 | 0.02 | 0.03–0.09 | < 0.01 | 0.05 | 0.02 | 0.00–0.09 | 0.03 |
Body-mass index (kg/m2) | − 0.14 | 0.12 | − 0.37–0.10 | 0.25 | – | – | – | – |
Diabetes mellitus (%) | 0.00 | 0.04 | − 0.08–0.08 | 0.95 | – | – | – | – |
Hypertension (%) | 0.04 | 0.03 | − 0.01–0.09 | 0.15 | – | – | – | – |
Active malignancy (%) | − 0.06 | 0.09 | − 0.24–0.13 | 0.54 | − | – | – | – |
Previous VTE (%) | 0.08 | 0.11 | − 0.13–0.28 | 0.48 | – | – | – | – |
Platelet count | 0.03 | 0.01 | 0.01–0.05 | 0.01 | 0.01 | 0.01 | − 0.01–0.02 | 0.42 |
D-dimer level | 0.00 | 0.00 | − 0.00–0.01 | 0.44 | – | – | – | – |
Patients on therapeutic anticoagulation (%) | 0.02 | 0.01 | 0.01–0.03 | < 0.01 | 0.01 | 0.01 | − 0.01–0.03 | 0.24 |
Patients intubated (%) | 0.03 | 0.04 | − 0.04–0.10 | 0.43 | – | – | – | – |
Patients on inotropes (%) | 0.03 | 0.03 | − 0.03–0.09 | 0.36 | – | – | – | – |
Patients on RRT (%) | − 0.02 | 0.04 | − 0.09–0.06 | 0.66 | – | – | – | – |
Patients on ECMO (%) | 0.07 | 0.15 | − 0.21–0.35 | 0.63 | – | – | – | – |