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Table 1 Baseline characteristics of individuals by cohorts

From: Development and validation of an online model to predict critical COVID-19 with immune-inflammatory parameters

Characteristics

Training cohort

Internal validation cohort

External validation cohort

(N = 111)

(N = 111)

(N = 228)

Demographics

 Age, years

62 (54.5-72)

64 (52-70.5)

63 (50-70)

 Sex

  Female

65 (58.56%)

53 (47.75%)

116 (50.88%)

  Male

46 (41.44%)

58 (52.25%)

112 (49.12%)

Clinical characteristics

 Comorbidity number

1 (0-2)

1 (1-2)

1 (0-2)

 Comorbidity

  Hypertension

40 (36.04%)

52 (46.85%)

86 (37.72%)

  Diabetes

21 (18.92%)

26 (23.42%)

41 (17.98%)

  Coronary heart disease

6 (5.41%)

12 (10.81%)

16 (7.02%)

  Tumor

8 (7.21%)

12 (10.81%)

17 (7.46%)

  COPD

1 (0.9%)

2 (1.8%)

2 (0.88%)

Symptoms at admission

 Fever

97 (87.39%)

90 (81.08%)

166 (72.81%)

 Temp (max) ≥ 39 °C

28 (25.23%)

24 (21.62%)

45 (19.74%)

 Cough

78 (70.27%)

79 (71.17%)

170 (74.56%)

 Dyspnea

56 (50.45%)

51 (45.95%)

88 (38.6%)

 Sputum

44 (39.64%)

49 (44.14%)

108 (47.37%)

 Fatigue

48 (43.24%)

49 (44.14%)

56 (24.56%)

 Diarrhea

31 (27.93%)

34 (30.63%)

35 (15.35%)

 Myalgia

23 (20.72%)

36 (32.43%)

34 (14.91%)

 Nausea or vomiting

3 (2.7%)

7 (6.31%)

2 (0.88%)

Vital status

 Critical illness

12 (10.81%)

16 (14.41%)

25 (10.96%)

 Noncritical illness

99 (89.19%)

95 (85.59%)

203 (89.04%)

Follow-up

 Time to critical illness, days

25 (14.5-34)

25 (10-30.5)

18.5 (11.75-30.25)

  1. Continuous variables were presented as median (interquartile ranges [IQR]) while categorical variables as counts and percentages (%)
  2. COPD, chronic obstructive pulmonary disease