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Table 3 Multivariable analysis for having ARDS associated with non-pulmonary sepsis (n = 594)

From: Risk modifiers of acute respiratory distress syndrome in patients with non-pulmonary sepsis: a retrospective analysis of the FORECAST study

Variable Odds ratio (95% CI)P value
Age at admission—per year 0.99 (0.97–1.01)0.29
Male gender 1.33 (0.71–2.49)0.37
Admission sourceHospital wards and other hospitalsReference 
Emergency department1.89 (1.06–3.40)0.03
Intensive care unit0.96 (0.25–3.65)0.95
Body mass index—kg/m2 1.04 (0.98–1.09)0.19
SmokingNeverReference 
Former0.77 (0.39–1.54)0.46
Current0.18 (0.06–0.59)0.004
Coexisting conditionsCongestive heart failure0.72 (0.26–1.88)0.50
COPD1.54 (0.46–5.21)0.49
Diabetes mellitus0.69 (0.35–1.37)0.29
Regular medicationGlucocorticoids0.48 (0.19–1.22)0.12
Statin0.36 (0.10–1.24)0.11
Site of infectionAbdomenReference 
Urinary tract0.71 (0.33–1.55)0.39
Soft tissue2.37 (1.04–5.40)0.04
Other than abdomen, urinary tract, or soft tissue1.57 (0.74–3.32)0.24
Septic shock 1.43 (0.74–2.78)0.29
APACHE II score—per point 1.08 (1.05–1.12)< 0.001
  1. ARDS acute respiratory distress syndrome, CI confidence interval, COPD chronic obstructive pulmonary disease, APACHE II acute physiology and chronic health evaluation II
  2. Definition of categorical variables: other than abdomen, urinary tract, or soft tissue = central nervous system, intravenous catheter, osteoarticular, endocardium, wound, implant device, and others
  3. Missing data (due to missing data of each outcome measures): admission source = 1; body mass index = 9; smoking = 45; APACHE II score = 53