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Table 2 Mixed-effects model analysis for sedation, pain, withdrawal and delirium

From: Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial

Variables

Control

Mean (SD)

Music

Mean (SD)

Mixed-effects model Effect size

(95% CI)

P value

Noise cancellation

Mean (SD)

Mixed-effects model Effect size

(95% CI)

P value

Sedation intensity Score/day

47.6 (26.0)

53.7 (36.9)

7.08 (− 7.56, 21.73)

0.340

55.6 (26.1)

6.63 (− 8.02, 21.25)

0.371

Sedation frequency/day

8.58 (6.11)

9.75 (7.10)

1.43 (− 1.71, 4.58)

0.368

10.9 (8.14)

1.71 (− 1.45, 4.84)

0.282

SBS

− 0.76 (0.87)

− 0.74 (0.95)

0.12 (− 0.32, 0.56)

0.595

− 0.53 (0.96)

0.06 (− 0.37, 0.50)

0.772

FLACC

1.30 (1.36)

1.17 (1.26)

− 0.08 (− 0.71, 0.55)

0.796

1.62 (1.72)

0.10 (− 0.53, 0.73)

0.751

WAT-1

1.12 (1.17)

1.85 (1.54)

0.82 (0.15, 1.49)

0.020

1.65 (1.14)

0.48 (− 0.19, 1.14)

0.166

CAPD

12.47 (4.56)

13.09 (5.54)

1.18 (− 1.45, 3.81)

0.384

13.86 (4.66)

1.70 (− 0.86, 4.27)

0.199

  1. SBS State Behavioral Scale (scale range from − 3 to + 2 with higher score indicating more agitation), FLACC Face Legs Activity Cry Consolability scale (scale range from 0 to 10 with higher score indicating higher pain), WAT-1 Withdrawal Assessment Tool (scores range from 0 to 12 with higher score indicating more withdrawal symptoms), CAPD Cornell Assessment of Pediatric Delirium (score ranges from 0 to 32 with higher score indicating higher risk of delirium)