No. of patients
|
118
|
116
| |
Demographics:
|
Gender (female)
|
35 (30%)
|
42 (36%)
|
0.29
|
Race (non-white)
|
26 (23%)
|
15 (13%)
|
0.07
|
Age (years)
|
56 (17)
|
57 (15)
|
0.59
|
Admission weight (kg)
|
82.5 [66.1-104.4]
|
82.5 [70.1-102.4]
|
0.63
|
Comorbidities:
|
Congestive heart failure
|
38 (32%)
|
61 (53%)
|
0.002
|
Chronic lung disease
|
38 (32%)
|
37 (32%)
|
0.96
|
Cirrhosis
|
5 (4%)
|
4 (3%)
|
0.75
|
ARDS risk factors:
|
Sepsis
|
57 (48%)
|
55 (47%)
|
0.89
|
Trauma
|
46 (39%)
|
26 (22%)
|
0.006
|
ICU admission from operating room
|
17 (14%)
|
21 (18%)
|
0.44
|
ICU type:
|
-
|
-
|
0.0003b
|
Medical ICU
|
37 (31%)
|
18 (16%)
| |
Cardiothoracic ICU
|
12 (10%)
|
33 (28%)
| |
Trauma-surgical ICU
|
38 (32%)
|
27 (23%)
| |
Other ICU
|
31 (26%)
|
38 (33%)
| |
Prior to ARDS:
|
Hospital length of stay (days)
|
1 [0–4]
|
1 [0–3.5]
|
0.44
|
Mechanical ventilation (days)
|
0 [0–1]
|
0 [0–1]
|
0.15
|
SOFA score, day 0
|
10.3 (2.9)
|
10.5 (2.9)
|
0.64
|
During ARDS hours 0–48:
|
Shock
|
85 (78%)
|
88 (76%)
|
0.51
|
Acute Kidney Injury
|
22 (19%)
|
15 (13%)
|
0.23
|
Lowest PaO2:FiO2 ≤ 150
|
118 (100%)
|
116 (100%)
| |
Any CVP measured
|
24 (20%)
|
44 (38%)
|
0.0031
|
Any transfusion
|
32 (27%)
|
31 (27%)
|
0.95
|
Volume overload at 48 h
|
30 (25%)
|
19 (16%)
|
0.09
|
During ARDS hours 48–72:
|
Shock
|
55 (47%)
|
48 (41%)
|
0.42
|
Acute Kidney Injury
|
19 (16%)
|
12 (10%)
|
0.19
|
Lowest PaO2:FiO2 ≤ 150
|
11 (9%)
|
16 (14%)
|
0.28
|
Any CVP measured
|
10 (8%)
|
32 (28%)
|
0.0001
|
Any transfusion
|
13 (11%)
|
6 (5%)
|
0.1
|
Weight measured
|
68 (58%)
|
85 (73%)
|
0.012
|
Total furosemide dosec (mg/24 h)
|
–
|
40 [20-80]
|
–
|
Outcomes
|
RRT in first 7 days after ARDS
|
5 (4%)
|
2 (2%)
|
0.26
|
Duration of MV, all (days)
|
7 [3–13]
|
5 [3–9]
|
0.034
|
Duration of MV, survivors (days)
|
5 [3–13]
|
5 [3–8.5]
|
0.13
|
Discharge home self-care
|
37 (31%)
|
47 (41%)
|
0.15
|
Died in hospital
|
30 (25%)
|
16 (14%)
|
0.026
|