Variable | All patients, n = 4987 | Non-SAE patients, n = 2513 | SAE patients, n = 2474 | P value |
---|---|---|---|---|
Age, years | 70 [56, 81] | 68 [55, 79] | 73 [58, 83] | < 0.001 |
Gender, male | 2680 (53.74) | 1434 (57.06) | 1246 (50.36) | < 0.001 |
Ethnicity,n(%) | Â | Â | Â | 0.002 |
 White | 3700 (74.19) | 1845 (73.42) | 1855 (74.98) |  |
 Black | 380 (7.62) | 166 (6.61) | 214 (8.65) |  |
 Hispanic or Latino | 145 (2.91) | 78 (3.10) | 67 (2.71) |  |
 Asian | 106 (2.13) | 56 (2.23) | 50 (2.02) |  |
 Others | 656 (13.15) | 368 (14.64) | 288 (11.64) |  |
Comorbidity,n(%) | Â | Â | Â | Â |
 Cardiovascular diseases | 2772 (55.58) | 1413 (56.23) | 1359 (54.93) | 0.372 |
 Peripheral vascular disease | 552 (11.07) | 299 (11.90) | 253 (10.23) | 0.066 |
 Other neurological diseases | 683 (13.70) | 189 (7.52) | 494 (19.97) | < 0.001 |
 Hypertension | 2457 (49.27) | 1181 (47.00) | 1276 (51.58) | 0.001 |
 Chronic pulmonary disease | 1136 (22.78) | 593 (23.60) | 543 (21.95) | 0.176 |
 Diabetes | 909 (18.23) | 449 (17.87) | 460 (18.59) | 0.530 |
 Hypothyroidism | 579 (11.61) | 272 (10.82) | 307 (12.41) | 0.089 |
 Liver disease | 421 (8.44) | 215 (8.56) | 206 (8.33) | 0.811 |
 Coagulopathy | 880 (17.65) | 476 (18.94) | 404 (16.33) | 0.017 |
 Anemias | 1303 (26.13) | 625 (24.87) | 678 (27.41) | 0.045 |