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Table 7 Cox proportional regression analysis evaluating ROX > 7.00 and ROX-HR > 8.00 for the prediction of HFNC failure in patients initiated on HFNC after a planned extubation

From: Early prediction of high flow nasal cannula therapy outcomes using a modified ROX index incorporating heart rate

  

Univariate analysis

p value

Multivariate analysis

p value

ROX > 7.00

2 h

0.519 (0.184–1.459)

0.213

0.405 (0.141–1.164)

0.093

6 h

0.348 (0.106–1.142)

0.082

0.356 (0.108–1.171)

0.089

10 h

0.251 (0.076–0.826)

0.023

0.287 (0.083–0.998)

0.050

18 h

0.473 (0.133–1.680)

0.247

0.431 (0.121–1.539)

0.195

24 h

0.169 (0.035–0.814)

0.027

0.173 (0.036–0.833)

0.029

ROX-HR > 8.00

2 h

0.459 (0.163–1.292)

0.140

0.483 (0.171–1.364)

0.169

6 h

0.266 (0.078–0.913)

0.035

0.305 (0.086–1.079)

0.065

10 h

0.176 (0.051–0.604)

0.006

0.194 (0.053–0.709)

0.013

18 h

0.578 (0.149–2.238)

0.427

0.426 (0.106–1.719)

0.231

24 h

0.296 (0.074–1.186)

0.086

0.303 (0075–1.215)

0.092

  1. Variables included in the multivariate analysis: immunocompromised host