Table 5 Prediction of HFNC success based on ROX and ROX-HR cut offs at different time points
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | LR+ | LR− | |
|---|---|---|---|---|---|---|
A. Prediction of HFNC success for patients initiated on HFNC for acute respiratory failure | ||||||
2-h ROX-HR > 6.80 | 55.56 | 74.41 | 73.17 | 57.14 | 2.17 | 0.60 |
2-h ROX > 5.80 | 61.11 | 67.44 | 70.21 | 58.00 | 1.87 | 0.58 |
6-h ROX-HR > 6.80 | 70.00 | 57.14 | 70.00 | 57.14 | 1.63 | 0.53 |
6-h ROX > 5.80 | 74.00 | 57.14 | 71.15 | 60.60 | 1.73 | 0.46 |
10-h ROX-HR > 6.80 | 78.26 | 58.62 | 75.00 | 62.96 | 1.89 | 0.37 |
10-h ROX > 5.80 | 78.26 | 58.62 | 75.00 | 62.96 | 1.89 | 0.37 |
18-h ROX-HR > 6.80 | 80.00 | 55.00 | 78.05 | 57.89 | 1.78 | 0.36 |
18-h ROX > 5.80 | 87.50 | 35.00 | 72.92 | 58.33 | 1.35 | 0.36 |
24-h ROX-HR > 6.80 | 81.82 | 64.29 | 84.39 | 60.00 | 2.29 | 0.28 |
24-h ROX > 5.80 | 84.85 | 57.14 | 82.35 | 61.54 | 1.98 | 0.27 |
B. Prediction of HFNC success for patients initiated on HFNC after a planned extubation | ||||||
2-h ROX-HR > 8.00 | 82.10 | 40.00 | 71.90 | 54.50 | 1.37 | 0.45 |
2-h ROX > 7.00 | 78.60 | 40.00 | 71.00 | 50.00 | 1.31 | 0.54 |
6-h ROX-HR > 8.00 | 74.10 | 63.60 | 83.30 | 50.00 | 2.04 | 0.41 |
6-h ROX > 7.00 | 74.10 | 54.50 | 80.00 | 46.20 | 1.63 | 0.48 |
10-h ROX-HR > 8.00 | 84.60 | 63.60 | 84.60 | 63.60 | 2.32 | 0.24 |
10-h ROX > 7.00 | 84.60 | 54.50 | 81.50 | 60.00 | 1.86 | 0.28 |
18-h ROX-HR > 8.00 | 82.60 | 30.00 | 73.10 | 42.90 | 1.18 | 0.58 |
18-h ROX > 7.00 | 78.30 | 40.00 | 75.00 | 44.40 | 1.31 | 0.54 |
24-h ROX-HR > 8.00 | 66.70 | 66.70 | 82.40 | 46.20 | 2.00 | 0.50 |
24-h ROX > 7.00 | 71.40 | 77.80 | 88.20 | 53.80 | 3.22 | 0.37 |