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Table 3 Management of candidemia

From: Impact of host- and early treatment-related factors on mortality in ICU patients with candidemia: a bicentric retrospective observational study

Variables

Total cohort (n = 68)

30-day survivors (n = 31)

30-day non-survivors (n = 37)

P value

Initial antifungal agent*

 Micafungin

41 (60.3)

19 (61.3)

22 (59.5)

1.000

 Liposomal amphotericin B

11 (16.2)

6 (19.4)

5 (13.5)

0.531

 Fluconazole

7 (10.3)

2 (6.5)

5 (13.5)

0.442

 Voriconazole

3 (4.4)

2 (6.5)

1 (2.7)

0.588

 None during candidemia

7 (10.3)

2 (6.5)

5 (13.5)

0.442

Treatment ≤ 24 h following onset

 Appropriate antifungal therapy alone

4 (5.9)

3 (9.7)

1 (2.7)

0.324

 CVC removal alone

19 (27.9)

9 (29.0)

10 (27.0)

1.000

 Combined intervention

5 (7.4)

2 (6.5)

3 (8.1)

1.000

Treatment ≤ 48 h following onset

 Appropriate antifungal therapy alone

9 (13.2)

3 (9.7)

6 (16.2)

0.494

 CVC removal alone

18 (26.5)

8 (25.8)

10 (27.0)

1.000

 Combined intervention

16 (23.5)

9 (29.0)

7 (18.9)

0.396

  1. Values are given as n (%). CVC central venous catheter
  2. *Including antifungal agents used in inappropriate antifungal therapy