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Table 3 MDW improves the odds of detecting Sepsis-2 among ED patients presenting with SIRS criteria

From: Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

  1. Ninety-eight percent of the patients presenting to the ED who developed sepsis within 12 h of ED admission (Sepsis-2) had 0–3 abnormal SIRS parameters at the time of initial ED evaluation. Abnormal MDW predicted higher probability of sepsis compared to SIRS criteria alone (unknown MDW) or with normal MDW. Overall, abnormal MDW was associated with 6.2-fold higher odds of sepsis compared to normal MDW in all septic patients at the time of initial ED presentation. For this analysis, the pre-test probability for sepsis in the ED was estimated at 8%