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Table 2 Median values and ranges of each oximetry index and response pattern counts

From: Spinal cord autoregulation using near-infrared spectroscopy under normal, hypovolemic, and post-fluid resuscitation conditions in a swine model: a comparison with cerebral autoregulation

Cerebral oximetry index (n = 10)
DoseBaselineHypovolemiaFluid resuscitation
PhenylephrineSNPPhenylephrinePhenylephrineSNP
0.50.05 (− 0.83 to 0.89)0.76 (0.10 to 0.97)0.36 (− 0.30 to 0.77)0.15 (− 0.51 to 0.85)0.77 (− 0.28 to 0.98)
1− 0.41 (− 0.81 to 0.86)0.27 (− 0.20 to 0.97)0.27 (− 0.19 to 0.76)ǁ0.10 (− 0.42 to 0.67)0.70 (0.03 to 0.96)
2− 0.21 (− 0.88 to 0.63)0.81 (0.34 to 0.96)0.12 (− 0.76 to 0.86)− 0.03 (− 0.88 to 0.72)0.91 (0.31 to 0.96)
5− 0.66 (− 0.93 to 0.92)0.93 (0.00 to 0.98)− 0.31 (− 0.87 to 0.71)− 0.31 (− 0.85 to 0.79)0.95 (0.87 to 0.98)
Response pattern counts (Pressure-passive/intact autoregulation/paradoxical response)
0.53/4/37/3/05/5/04/5/18/2/0
11/3/64/6/04/6/03/5/27/3/0
21/5/49/1/03/3/41/6/39/1/0
51/2/79/1/02/3/51/5/410/0/0
Thoracic spinal cord oximetry index (n = 10)
DoseBaselineHypovolemiaFluid resuscitation
PhenylephrineSNPPhenylephrinePhenylephrineSNP
0.50.44 (− 0.87 to 0.91)0.89 (0.76 to 0.96)0.75 (0.00 to 0.93)0.12 (− 0.82 to 0.79)0.89 (0.47 to 0.94)
10.49 (− 0.85 to 0.86)0.80 (− 0.32 to 0.93)0.44 (− 0.24 to 0.92)0.25 (− 0.72 to 0.57)0.72 (− 0.50 to 0.89)
20.57 (− 0.78 to 0.96)0.82 (0.25 to 0.89)0.78 (− 0.38 to 0.91)0.55 (− 0.64 to 0.87)0.83 (− 0.41 to 0.90)
50.29 (− 0.57 to 0.82)0.80 (0.23 to 0.93)0.53 (0.06 to 0.87)− 0.11 (− 0.85 to 0.60)0.84 (0.57 to 0.96)
Response pattern counts (Pressure-passive/intact autoregulation/paradoxical response)
0.56/3/110/0/08/2/04/4/210/0/0
15/2/38/2/06/4/02/6/29/0/1
27/1/29/1/07/2/17/2/19/0/1
55/4/19/1/06/4/03/3/410/0/0
Lumbar spinal cord oximetry index (n = 9)
DoseBaselineHypovolemiaFluid resuscitation
PhenylephrineSNPPhenylephrinePhenylephrineSNP
0.50.46 (− 0.88 to 0.92)0.86 (0.51 to 0.96)0.59 (0.12 to 0.80)− 0.04 (− 0.19 to 0.68)0.87 (0.44 to 0.93)
10.22 (− 0.87 to 0.83)0.45 (− 0.47 to 0.88)*0.46 (− 0.32 to 0.92)0.00 (− 0.34 to 0.58)0.68 (0.31 to 0.84)
20.45 (− 0.90 to 0.97)0.80 (0.54 to 0.89)0.68 (− 0.39 to 0.92)0.45 (− 0.87 to 0.91)0.87 (0.61 to 0.94)
5− 0.11 (− 0.99 to 0.63)0.75 (0.53 to 0.85)0.36 (− 0.33 to 0.97)0.02 (− 0.87 to 0.43)0.85 (0.65 to 0.97)
Response pattern counts (pressure-passive/intact autoregulation/paradoxical response)
0.55/2/29/0/06/3/04/5/09/0/0
14/2/35/3/15/4/02/7/08/1/0
27/1/19/0/06/2/15/3/19/0/0
52/5/29/0/05/4/02/4/39/0/0
  1. Dose each vasoactive drug infusion dose (μg kg−1 min−1), SNP sodium nitroprusside. Response patterns were defined as follows: an oximetry index > 0.36 was defined as pressure-passive, an oximetry index between − 0.36 and 0.36 was defined as intact autoregulation, and an oximetry index < − 0.36 was defined as a paradoxical response
  2. *P < 0.05 versus 0.5 μg kg−1 min−1; P < 0.05 versus 1 μg kg−1 min−1; ǁP < 0.05 versus the same dose of phenylephrine infusion in the baseline condition