|
Weaning outcome measures
|
All patients (n = 263)
|
Weaning success (n = 126)
|
Weaning failure (n = 137)
|
P valuea
|
|---|
|
Weaning success
|
126 (47.9)
|
126 (100)
|
–
|
–
|
|
Weaning failure
|
137 (52.1)
|
–
|
137 (100.0)
|
–
|
|
HMV-NIV
|
50 (19.0)
|
–
|
50 (36.5)
|
–
|
|
HMV-IMV
|
74 (28.1)
|
–
|
74 (54.0)
|
–
|
|
Death on MV
|
13 (4.9)
|
–
|
13 (9.5)
|
–
|
|
Weaning duration from first SBT (days)
|
22.9 (± 16.1)
|
19.0 (± 11.7)
|
26.6 (± 18.5)
|
< 0.001b
|
|
Duration of mechanical ventilation (days)
|
52.2 (± 28.6)
|
45.2 (± 22.1)
|
58.6 (± 32.1)
|
< 0.001b
|
|
Decannulation
|
135 (51.3)
|
85 (67.5)
|
50 (36.5)
|
< 0.001c
|
|
SB on discharge from hospital (hours per day)d
|
16.1 (± 8.9)
|
21.9 (± 6.5)
|
10.9 (± 7.5)
|
< 0.001b
|
|
LTOT on discharge
|
183 (78.9)
|
74 (63.8)
|
109 (94.0)
|
< 0.001c
|
|
Weaning unit-LOS (days)
|
48.3 (± 28.5)
|
40.8 (± 21.7)
|
55.1 (± 32.0)
|
< 0.001b
|
|
Hospital-LOS (days)
|
52.8 (± 28.6)
|
45.6 (± 22.2)
|
59.5 (± 32.0)
|
< 0.001b
|
|
Hospital mortality
|
38 (14.4)
|
13 (10.3)
|
25 (18.2)
|
0.068c
|
- Continuous variables are presented as mean values (± standard deviation); categorical variables are presented as number (%)
- aP value for differences between patients with weaning success and weaning failure
- bStudent’s t test
- cChi-squared test
- dValues for deceased patients were set at 0 h
- HMV-NIV home mechanical ventilation-non-invasive mechanical ventilation, HMV-IMV home mechanical ventilation-invasive mechanical ventilation, IMV invasive mechanical ventilation, SB spontaneous breathing, LTOT long-term oxygen therapy, SBT spontaneous breathing trial, LOS length of stay
