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Table 4 Survival analysis assessing 28-day mortality, patient characteristics, and circadian rhythm parameters of the temperature according to head trauma

From: Circadian disruption of core body temperature in trauma patients: a single-center retrospective observational study

 Head traumaNo head trauma
UnivariateMultivariateUnivariateMultivariate
HR [95% CI]pHR [95% CI]pHR [95% CI]pHR [95% CI]p
Clinical variables
 Age1.04 [1.02–1.06]< 0.0011.04 [1.02–1.06]< 0.0011.07 [1.03–1.12]< 0.0011.10 [1.04–1.17]< 0.001
 Sex (male)1.68 [0.74–3.82]0.22  2.36 [0.29–19.17]0.42  
 Body mass index0.91 [0.82–1.01]0.07  0.90 [0.73–1.10]0.30  
 Glasgow Coma Scale0.96 [0.87–1.05]0.33  0.84 [0.75–0.95]0.0040.77 (0.65–0.91)0.003
 Intracranial hypertensiona7.55 [3.15–18.12]< 0.001  
 Surgery at admission0.90 [0.47–1.72]0.75  0.71 [0.14–3.52]0.68  
 ISS1.01 [0.98–1.04]0.47  1.01 [0.97–1.06]0.57  
Temperature rhythm
 Period1.00 [0.97–1.02]0.74  1.05 [0.99–1.11]0.11  
 Mesor0.41 [0.25–0.65]< 0.0010.40 [0.23–0.70]0.0010.73 [0.23–2.29]0.59  
 Amplitude4.48 [1.24–19.20]0.024.73 [1.38–16.22]0.016.10 [1.06–35.25]0.042.94 [0.50–17.25]0.23
  1. The analyses were performed using Cox regression model to estimate hazard ratios (HR) and their 95% confidence intervals (95% CIs)
  2. aIntracranial hypertension not included in the multivariate analysis owing to collinearity with head trauma