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Table 3 Mortality of all encephalopathic critically ill oncological patients

From: Non-convulsive seizures in the encephalopathic critically ill cancer patient does not necessarily portend a poor prognosis

Variable All patients Survived Dead p value
(n = 317) (n = 193) (n = 124)
Age 60.2 ± 14.6, 62 (18–89) 58.9 ± 15.5, 62 (18–87) 61.1 ± 14, 62 (18, 89) 0.34
Gender (male) 59.3% 56.5% 61.1% 0.407
Type of malignancy     0.609
 Hematological 61.8% 58.9% 63.7% 0.385
 Solid tumor 38.2% 41.1% 36.3%  
Metastatic disease 72.7% 92.7% 74.2% 0.035
Active disease (no remission) 86.8% 82.3% 89.6% 0.059
Stem cell transplant (yes) 31.6% 21.8% 18.1% 0.214
Co-morbidity index ≥ 5 68.5% 66.1% 69.9% 0.475
Chemotherapy within 10 days 24.3% 28.2% 21.8% 0.190
CNS malignancy involvement* 26.5% 33.9% 21.8% 0.017
Medical history of seizure disorder 10.4% 16.1% 10.9% 0.008
Medical service 89.3% 83.0% 94.8% 0.006
Variables during ICU stay     
SOFA on admission** 8.5 ± 3.7, 8 (0–19) 7.2 ± 3.3, 7 (0–16) 9.3 ± 3.8, 9 (2–19) < 0.0001
SOFA at time of EEG # 9.9 ± 4.0, 10 (3–22) 8.2 ± 3.7, 7 (3–21) 11.1 ± 3.7, 11 (3–22) < 0.0001
GCS at time of EEG## (median) 7 (3–12) 8 (3–12) 7 (3–12) 0.001
Vasopressors (yes) 56.5% 35.5% 69.9% < 0.0001
Acute renal failure (yes) 52.4% 31.5% 65.8% < 0.0001
Mechanical Ventilation (yes) 79.5% 66.9% 87.6% < 0.0001
Use of sedatives (yes) 49.8% 44.4% 53.4% 0.117
Cardiac arrest during ICU stay 13.3% 3.2% 19.7% < 0.0001
  1. *Central nervous system
  2. **Sequential Organ Failure Assessment
  3. #Electroencephalogram
  4. ##Glasgow Coma Score