Variable | Total cohort (n = 450) | Patients with sepsis (n = 180) | Patients without sepsis (n = 270) | p value |
---|---|---|---|---|
Severity Indicators | ||||
Microbes detecteda | 202 (45.5) | 112 (62.9) | 90 (33.8) | < 0.001 |
Acute kidney failurec | 82 (22.2) | 46 (31.5) | 36 (16.1) | < 0.001 |
Tumor lysis syndromec | 6 (1.6) | 3 (2.1) | 3 (1.4) | 0.590 |
Graft-versus-host diseasec | 20 (5.4) | 7 (4.9) | 13 (5.8) | 0.708 |
Glasgow Coma Scaled, mean (SD) | 14.0 (2.9) | 13.3 (3.6) | 14.4 (2.2) | < 0.001 |
Outcomes | ||||
Overall in-hospital mortality | 109 (24.3) | 71 (39.7) | 38 (14.1) | < 0.001 |
ICU mortality | 80 (44.4) | 52 (51.5) | 28 (35.0) | 0.023 |
Length of staye, median days (IQR) | 26 (16–41) | 28 (15–44) | 25.5 (17–40) | 0.554 |
Transfer from regular ward to ICUe | 49 (18.3) | 27 (34.2) | 22 (11.6) | 0.005 |
Sepsis scoresf | ||||
SIRS ≥ 2 | 351 (80.1), n = 438 | 150 (85.7), n = 175 | 201 (76.4), n = 263 | 0.017 |
SOFA ≥ 2 | 173 (42.2), n = 410 | 112 (64.0), n = 175 | 61 (26.0), n = 235 | < 0.001 |
qSOFA ≥ 2 | 90 (22.0), n = 410 | 68 (41.5), n = 164 | 22 (8.9), n = 246 | < 0.001 |
Septic shock | 20 (4.5), n = 441 | 20 (11.7), n = 171 | – | < 0.001 |
SIRS < 2 | 3 (15.0) | 3 (15.0) | ||
SOFA < 2 | 2 (10.0) | 2 (10.0) | ||
qSOFA < 2 | 4 (20.0) | 4 (20.0) | ||
ICU (n = 181) | ||||
Severity and septic shock indicators | ||||
APACHE IId, mean (SD) | 22.3 (8.0) | 24.1 (8.0) | 20 (7.5) | < 0.001 |
Hypotension (MAP < 65 mmHg)a | 46 (25.8) | 33 (33.3) | 13 (16.5) | < 0.001 |
Use of vasopressorsa | 97 (54.2) | 65 (65.6) | 32 (40.0) | < 0.001 |
Lactate > 2 mmol/Lb | 78 (47.0) | 46 (48.9) | 32 (44.4) | 0.226 |