Timing of administration of epinephrine predicts the responsiveness to epinephrine in norepinephrine-refractory septic shock: a retrospective study

Table 4 Multivariable logistic analyses of predicting factors for survival from shock and 28-day survival

Variable	OR (95% CI)	P value
Association with survival from shock*
Log time-epi	0.42 (0.23–0.77)	0.005
SOFA score ≥ 14	0.41 (0.09–1.84)	0.247
Association with 28-day survival
Log time-epi	0.14 (0.04–0.57)	0.006
SOFA score ≥ 14	0.6 (0.14–2.53)	0.488

OR odds ratio, CI confidence interval, Time-epi time of epinephrine administration after intensive care unit admission, SOFA Sequential Organ Failure Assessment
*7-day survival without the use of mechanical circulatory support