Timing of administration of epinephrine predicts the responsiveness to epinephrine in norepinephrine-refractory septic shock: a retrospective study

Table 3 Multivariable logistic regression analyses of predicting factors of epinephrine response

Variable	OR (95% CI)	P value
Log time-epi	0.48 (0.27–0.84)	0.011
SOFA score ≥ 14	0.19 (0.04–0.88)	0.034
Adjusted using IPTW-propensity score*
Time-epi ≥ 24 h	0.07 (0.02–0.21)	< 0.001

OR odds ratio, CI confidence interval, Time-epi time of epinephrine administration after intensive care unit admission, SOFA Sequential Organ Failure Assessment, IPTW inverse probability of treatment weighting
*Variables used to calculate the propensity score included age, lactate, steroid use, and SOFA score

ISSN: 2052-0492