|
Clinical parameter
|
Control
|
Surgical trauma
|
Sepsis
|
Septic shock
|
P value*
|
|---|
|
n
|
7
|
20
|
63
|
17
|
N/A
|
|
Age, years
|
31 (24–52)
|
61 (51–68)
|
60 (49–70)
|
60 (54–72)
|
ns
|
|
Male, n (%)
|
3 (42)
|
11 (55)
|
37 (62)
|
10 (58)
|
ns
|
|
SOFA score
|
N/A
|
4 (2–7)
|
5 (3–7)
|
11 (8–13)
|
< 0.0001
|
|
Leucocytes, ×109/L
|
6.3 (5.8–7.9)
|
13.0 (12.0–15.1)
|
14.0 (9.9–18.5)
|
14.6 (9.4–24.9)
|
ns
|
|
Interleukin-6, ng/L
|
N/D
|
129.4 (61.7–263.3)
|
123.4 (46.2–304.5)
|
464.9 (132.7–1568)
|
< 0.05#
|
|
Procalcitonin, μg/L
|
N/D
|
0.81 (0.28–3.06)
|
0.73 (0.25–1.76)
|
4.19 (1.53–9.27)
|
< 0.01#
|
|
C-reactive protein, mg/L
|
5.0 (5.0–5.5)
|
97.5 (68.2–190.8)
|
145 (72.0–239.0)
|
128 (100.5–222.0)
|
ns
|
|
Lactat, mmol/L
|
N/D
|
1.2 (0.92–1.7)
|
1.3 (1.0–1.6)
|
2.8 (2.2–5.4)
|
< 0.0001
|
|
ICU length of stay, days
|
N/A
|
2 (1–5)
|
7 (3–10)
|
13 (8–31)
|
< 0.0001
|
|
Invasive ventilation, n (%)
|
N/A
|
1 (5)
|
19 (30)
|
8 (47)
|
< 0.01#
|
|
Dialysis, n (%)
|
N/A
|
0 (0)
|
4 (6)
|
6 (35)
|
< 0.001#
|
|
Died, n (%)
|
N/A
|
0 (0)
|
10 (16)
|
5 (30)
|
< 0.05#
|
- SOFA Sequential Organ Failure Assessment score, ICU intensive care unit, N/A not applicable, N/D not determined, ns not significant. Data are presented as median (IQR). *P value for trend between patient groups using a non-parametric ANOVA Kruskal-Wallis test if not otherwise indicated. #Chi-square for trend analysis
