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Table 1 Characteristics of the study population

From: Association of abnormal carbon dioxide levels with poor neurological outcomes in aneurysmal subarachnoid hemorrhage: a retrospective observational study

Variables

All patients (N = 158)

Unfavorable outcome group (N = 73)

Favorable outcome group (N = 85)

p value

Age (years)

62.9 ± 15.9

69.6 ± 15.1

57.1 ± 14.4

< 0.01

Sex (male)

52 (32.9)

23 (31.5)

29 (34.1)

0.74

H&K grade

< 0.01

 I

13 (8.2)

3 (4.1)

10 (11.8)

 

 II

60 (38.0)

14 (19.2)

46 (54.1)

 

 III

41 (25.9)

22 (30.1)

19 (22.4)

 

 IV

29 (18.4)

23 (31.5)

6 (7.1)

 

 V

15 (9.5)

11 (15.1)

4 (4.7)

 

Treatment modality

0.27

 Coil

117 (74.1)

58 (79.5)

59 (69.4)

 

 Clip

39 (24.7)

14 (19.2)

25 (29.4)

 

Number of arterial blood gas analyses on days 1–14

43 [31–55]

53 [39–56]

40 [28–48]

< 0.01

Median PaCO2 on days 1–14 (mmHg)

39.0 [37.2–40.9]

38.4 [36.9–40.5]

39.4 [37.4–40.9]

0.11

SD of PaCO2 on days 1–14

3.63 [2.75–4.60]

4.05 [3.58–5.20]

2.97 [2.45–3.95]

< 0.01

Proportion of PaCO2 ≤ 30 among all blood gas analyses on days 1–14 (%)

0 [0–2]

2 [0–5]

0 [0–0]

< 0.01

Proportion of PaCO2 < 35 among all blood gas analyses on days 1–14 (%)

14 [3–26]

21 [9–35]

9 [2–22]

< 0.01

Proportion of PaCO2 > 45 among all blood gas analyses on days 1–14 (%)

4 [0–16]

7 [2–18]

2 [0–12]

< 0.05

Maximum PaCO2 level on days 1–14 (mmHg)

47.4 [43.7–51.0]

49.4 [45.6–51.9]

45.8 [42.9–49.8]

< 0.01

Minimum PaCO2 level on days 1–14 (mmHg)

31.0 [28.7–33.8]

29.4 [26.2–32.7]

31.7 [30.2–34.5]

< 0.01

Use of mechanical ventilation

156 (98.7)

73 (100)

83 (97.6)

0.50

Modified Rankin scale score

< 0.01

 0

29 (18.4)

0 (0.0)

29 (34.1)

 

 1

27 (17.1)

0 (0.0)

27 (31.8)

 

 2

29 (18.4)

0 (0.0)

29 (34.1)

 

 3

24 (15.2)

24 (32.9)

0 (0.0)

 

 4

27 (17.1)

27 (37.0)

0 (0.0)

 

 5

12 (7.6)

12 (16.4)

0 (0.0)

 

 6

10 (6.3)

10 (13.7)

0 (0.0)

 

DCI

23 (14.6)

16 (21.9)

7 (8.2)

< 0.05

Mechanical ventilation duration

2 [1–9]

9 [2–16]

1 [1–2]

< 0.01

ICU stay duration

15 [12–19]

17 [13–21]

14 [12–16]

< 0.01

Hospital stay duration

28 [22–51]

41 [26–74]

24 [21–30]

< 0.01

Hospital mortality

10 (6.3)

10 (13.7)

0 (0.0)

< 0.01

  1. Data are presented as mean ± standard deviation (SD), number (percentage), or median [interquartile range]
  2. H&K Hunt and Kosnik, DCI Delayed cerebral ischemia, ICU Intensive care unit