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Table 1 Parameters used in these models of virtual AKI patients receiving CRRT [14,15,16,17,18]

From: Cefepime dosing regimens in critically ill patients receiving continuous renal replacement therapy: a Monte Carlo simulation study

Pharmacokinetic parameters
Mean ± SD (range limits)
  Hemofiltration (HF) Hemodialysis (HD)
Weight (kg) 60.72 ± 14.5 (40–230)
Vd (L/kg) 0.5 ± 0.23 (0.21–1.11)
CLNR (mL/min) 24.33 ± 11.25 (13–44)
Free fraction 0.79 ± 0.09 (0.72–0.85)
SC or SA 0.79 ± 0.15 (0.47–0.92) 0.77 ± 0.09 (0.65–0.97)