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Table 2 Baseline characteristics of study population

From: Balanced crystalloids versus isotonic saline in critically ill patients: systematic review and meta-analysis

Study Name Fluid type Age (years) Gender CKD Baseline serum creatinine (mg/dl) Sepsis and/or septic shock MV Vasopressor ICU admission indication
Mean (SD) Median (IQR) Male Female   Mean Median Medical Surgical
Young [10] Balanced 60.1 (16.79) 64% 36% 0.98 (0.76)   4% 67% 29% 71%
Saline 60.95 (16.25)   67% 34%   0.99 (0.68)   4% 66%   28% 72%
Verma [16] Balanced 62 (45–70) 62% 38% 0.85 (0.58–1.34) 46% 58% 46% 58% 42%
Saline   64 (46–72) 64% 36%    0.9 (0.6–1.21) 41% 56% 32% 48% 52%
Semler [15] Balanced 58 (44–69) 57% 43% 17% 0.89 (0.47–1.1) 15% 34% 26% 78% 22%
Saline   58 (44–69) 58% 42% 17%   0.89 (0.47–1.1) 15% 35% 26% 79% 21%
Semler [11] Balanced 57 (44–68) 52% 48% 23% 25% 34% 22%
Saline   58 (46–70) 54% 46% 23%    29% 34% 25%   
Young [17] Balanced 38 (19) 73% 27%
Saline 39 (14)   79% 21%         
Ratanarat [18] Balanced
Saline             
  1. CKD chronic kidney disease, MV mechanical ventilator, ICU intensive care unit, SD standard deviation, IQR interquartile range