|
Study Name
|
Fluid type
|
Age (years)
|
Gender
|
CKD
|
Baseline serum creatinine (mg/dl)
|
Sepsis and/or septic shock
|
MV
|
Vasopressor
|
ICU admission indication
|
|---|
|
Mean (SD)
|
Median (IQR)
|
Male
|
Female
| |
Mean
|
Median
|
Medical
|
Surgical
|
|---|
|
Young [10]
|
Balanced
|
60.1 (16.79)
|
–
|
64%
|
36%
|
–
|
0.98 (0.76)
| |
4%
|
67%
|
–
|
29%
|
71%
|
|
Saline
|
60.95 (16.25)
| |
67%
|
34%
| |
0.99 (0.68)
| |
4%
|
66%
| |
28%
|
72%
|
|
Verma [16]
|
Balanced
|
–
|
62 (45–70)
|
62%
|
38%
|
–
|
–
|
0.85 (0.58–1.34)
|
46%
|
58%
|
46%
|
58%
|
42%
|
|
Saline
| |
64 (46–72)
|
64%
|
36%
| | |
0.9 (0.6–1.21)
|
41%
|
56%
|
32%
|
48%
|
52%
|
|
Semler [15]
|
Balanced
|
–
|
58 (44–69)
|
57%
|
43%
|
17%
|
–
|
0.89 (0.47–1.1)
|
15%
|
34%
|
26%
|
78%
|
22%
|
|
Saline
| |
58 (44–69)
|
58%
|
42%
|
17%
| |
0.89 (0.47–1.1)
|
15%
|
35%
|
26%
|
79%
|
21%
|
|
Semler [11]
|
Balanced
|
–
|
57 (44–68)
|
52%
|
48%
|
23%
|
–
|
–
|
25%
|
34%
|
22%
|
–
|
–
|
|
Saline
| |
58 (46–70)
|
54%
|
46%
|
23%
| | |
29%
|
34%
|
25%
| | |
|
Young [17]
|
Balanced
|
38 (19)
|
–
|
73%
|
27%
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Saline
|
39 (14)
| |
79%
|
21%
| | | | | | | | |
|
Ratanarat [18]
|
Balanced
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Saline
| | | | | | | | | | | | |
- CKD chronic kidney disease, MV mechanical ventilator, ICU intensive care unit, SD standard deviation, IQR interquartile range
