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Table 3 Multivariable logistic regression analysis of active smoking and mortality in severe sepsis and septic shock (current smokers vs. non-smokers)

From: The impact of smoking on patient outcomes in severe sepsis and septic shock

Risk factor Odds ratio (95% CI) P value
Current smoking 1.81 (0.92–3.54) 0.08
Alcohol abuse 1.17 (0.54–2.49) 0.69
72 h fluid balance 1.06 (0.99–1.13) 0.08
Age 1.02 (0.99–1.05) 0.06
Charlson score 1.16 (1.02–1.31) 0.02
SOFA 1.15 (1.068–1.238) < 0.01
COPD 0.98 (0.539–1.794) 0.96
Hospital acquired sepsis 1.51 (0.711–3.201) 0.28
Severe sepsis 0.54 (0.288–1.011) 0.05
Genitourinary infect 0.52 (0.282–0.970) 0.04
Abdominal 0.93 (0.487–1.757) 0.81
Soft tissue 1.03 (0.394–2.713) 0.95
Medical ICU admission 1.62 (0.765–3.411) 0.21
  1. All survival predictors (except for “respiratory”) that were noted to be significant (p < 0.1) on univariate analysis were included in this multivariate model
  2. SOFA sequential organ failure assessment, COPD chronic obstructive pulmonary disease