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Table 4 Evolution of ventilatory settings and gas exchanges in 11 COPD patients

From: Daily use of extracorporeal CO2 removal in a critical care unit: indications and results

Ventilatory parameters Baseline 4 h 8 h 12 h 24 h 48 h
Ventilatory mode (VC/PSV/NIV), number 8/2/1 7/3/1 7/3/1 7/3/1 5/5/1 5/5/1
TV (mL kg−1) 5.5 [5.5–5.9] 5 [4.4–6.1] 4.6 [4.4–4.8]* 4.5 [4.2–5]* 5.6 [4.4–5.8] 5.2 [4.1–5.8]
RR (min−1) 22 [20–23] 18 [17–22] 18 [15–24] 18 [15–21] 20 [17–20] 20 [16–24]
Minute ventilation (L min−1) 7.6 [6.6–8.7] 5.9 [5–7.2] 4.7 [3.8–5.2]* 4.9 [3.8–5.9]* 6.2 [4.1–6.8] 5.8 [4.9–6.2]*
PEEP (cmH2O) 6 [4–8] 6 [5–8] 6 [5–8] 6 [5–8] 8 [5–10] 8 [7–10]
PaCO2 (kPa) 9.4 [8.4–10.1] 6.6 [5.7–7.1]* 6 [5.1–7.1]* 6 [5.3–6.8]*
pH 7.32 [7.26–7.34] 7.43 [7.41–7.45]* 7.45 [7.41–7.47]* 7.44 [7.42–7.46]*
PaO2/FiO2 174 [158–207] 192 [177–254] 225 [186–262] 210 [181–254]
Sedative use, number 8 (72%)
6 (54%) 5 (45%)
Neuromuscular blockers use, number 6 (54%) 4 (36%) 3 (27%)
  1. *p < 0.05 vs baseline; VC volume control PSV pressure support ventilation, NIV noninvasive ventilation; 1when VC is used; numbers are n (%) and median (interquartile range)