Skip to main content

Table 4 Evolution of ventilatory settings and gas exchanges in 11 COPD patients

From: Daily use of extracorporeal CO2 removal in a critical care unit: indications and results

Ventilatory parameters

Baseline

4 h

8 h

12 h

24 h

48 h

Ventilatory mode (VC/PSV/NIV), number

8/2/1

7/3/1

7/3/1

7/3/1

5/5/1

5/5/1

TV (mL kg−1)

5.5 [5.5–5.9]

5 [4.4–6.1]

4.6 [4.4–4.8]*

4.5 [4.2–5]*

5.6 [4.4–5.8]

5.2 [4.1–5.8]

RR (min−1)

22 [20–23]

18 [17–22]

18 [15–24]

18 [15–21]

20 [17–20]

20 [16–24]

Minute ventilation (L min−1)

7.6 [6.6–8.7]

5.9 [5–7.2]

4.7 [3.8–5.2]*

4.9 [3.8–5.9]*

6.2 [4.1–6.8]

5.8 [4.9–6.2]*

PEEP (cmH2O)

6 [4–8]

6 [5–8]

6 [5–8]

6 [5–8]

8 [5–10]

8 [7–10]

PaCO2 (kPa)

9.4 [8.4–10.1]

6.6 [5.7–7.1]*

6 [5.1–7.1]*

6 [5.3–6.8]*

pH

7.32 [7.26–7.34]

7.43 [7.41–7.45]*

7.45 [7.41–7.47]*

7.44 [7.42–7.46]*

PaO2/FiO2

174 [158–207]

192 [177–254]

225 [186–262]

210 [181–254]

Sedative use, number

8 (72%)

6 (54%)

5 (45%)

Neuromuscular blockers use, number

6 (54%)

4 (36%)

3 (27%)

  1. *p < 0.05 vs baseline; VC volume control PSV pressure support ventilation, NIV noninvasive ventilation; 1when VC is used; numbers are n (%) and median (interquartile range)