Table 3 Summary of the association between hypernatremia and clinical outcomes
From: Aneurysmal subarachnoid hemorrhage: intensive care for improving neurological outcome
Article | Study design | Definition of hypernatremia (mmol/L) | Number of patient with hypernatremia/total number of patients | In-hospital mortality | Delayed cerebral ischemia | Neurological outcome |
|---|---|---|---|---|---|---|
Qureshi AI 2002 [68] | Post hoc analysis of RCT | > 145 | 58/298 (19.5%) | NA | NA | Worse at 3 months |
Wartenberg KE 2006 [69] | Post hoc analysis of single-center, prospective cohort study | > 150 | 91/576 (15.8%) | NA | NA | Not significant at 3 months |
Fisher LA 2006 [70] | Post hoc analysis of single-center, prospective cohort study | > 143 | 48/214 (22.4%) | Not significant | NA | NA |
Beseoglu K 2014 [67] | Single-center, retrospective cohort study | > 145 | 82/264 (31.1%) | NA | NA | Worse at 12 months |
Lantigua H 2015 [71] | Post hoc analysis of single-center, prospective cohort study | > 150 | 250/1200 (20.8%) | Higher | NA | NA |
Spatenkova V 2017 [72] | Single-center, retrospective and prospective observational study | > 150 | 41/334 (11.9%) | Higher | NA | Worse at 12 months |
Okazaki T 2017 [60] a | Single-center, retrospective observational study | ≧ 145 | 40/131 (30.5%) | NA | NA | Worse at hospital discharge |