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Table 2 Summary of glycemic control studies

From: Aneurysmal subarachnoid hemorrhage: intensive care for improving neurological outcome

Article

Design

Patient

Intervention or exposure

Comparison

Outcome

Main results

Thiele RH 2009 [52]

Single-center

Before–after study

Patients with the primary diagnosis of SAH

5.0–6.7 mmol/l

(90-120 mg/dl)

N = 491

No detail described

N = 343

In-hospital mortality

Three was no significant difference in in-hospital mortality.

Latorre JG 2009 [53]

Single-center

Before–after study

SAH patients with blood glucose > 11.1 mmol/l (200 mg/dl) on admission or the first 24 h mean blood glucose > 7.8 mmol/l (140 mg/dL)

4.4–7.8 mmol/l

(80-140 mg/dl)

N = 166

≦ 11.1 mmol/l

(200 mg/dl)

N = 166

mRS ≧ 4 at 3–6 months

Given temporal trend, there was no significant difference in neurological outcome.

Bilotta F. 2007 [54]

Single-center, randomized control trial

SAH patients undergoing emergency cerebral aneurysm clipping

4.4–6.7 mmol/l

(80–120 mg/dl)

N = 40

4.4–12.2 mmol/l

(80–220 mg/d)

N = 38

mRS ≧ 4 at 6 months (as secondary outcome)

There was no significant difference in neurological outcome.

  1. mRS modified Ranking Scale score