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Table 4 ICH vs. non-ICH cohorts: clinical variables

From: Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation: an observational cohort study

VariableICH cohort (n = 54)Non-ICH cohort (n = 199)p value
Administered blood productsa
 Plasma (mL)2804 (1434–5674) (3 missing, 6%)1873 (690–4887) (22 missing, 11%)0.061
 Platelets (mL)1239 (275–3265) (3 missing, 6%)370 (0–2072) (22 missing, 11%)0.004
 Erythrocyte concentrate (mL)3576 (2155–6848) (3 missing, 6%)2471 (1027–6531) (22 missing, 11%)0.014
Mean arterial pressureb (mmHg)99 (89–113) (1 missing, 2%)100 (92–109) (16 missing, 8%)0.791
Axillary temperature <36 °Ca 12 (23%) (1 missing, 2%)53 (29%) (16 missing, 8%)0.463
Spontaneous extracranial hemorrhagea 32 (59%)85 (43%)0.045
CPRc 11 (20%)34 (17%)0.719
Septic shocka 24 (44%)59 (30%)0.059
Dialysisa 52 (96%)171 (86%)0.063
Converted12 (22%)30 (15%)0.296
ECMO days at ICH diagnosis7 (4.0–14.5)
Days on ECMO12 (5–19)7 (4.0–15)0.057
1-month mortality44 (81%)52 (28%) (13 missing, 7%)<0.001
6-month mortality46 (85%)61 (33%) (13 missing, 7%)<0.001
  1. Values are expressed as median (interquartile range) or numbers (proportion)
  2. Italicized text in the p value column indicates a statistically significant correlation (p < 0.05)
  3. Abbreviations: ICH intracranial hemorrhage, CPR cardiopulmonary resuscitation, ECMO extracorporeal membrane oxygenation
  4. aDuring ECMO support and before ICH diagnosis (if applicable)
  5. bHighest value during ECMO support and before ICH diagnosis (if applicable)
  6. cDuring hospitalization and before ICH diagnosis (if applicable)