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Table 3 ICH vs. non-ICH cohorts: laboratory variables

From: Predictors of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation: an observational cohort study

Variable

ICH cohort (n = 54)

Non-ICH cohort (n = 199)

p value

Lab biochemistry

 Platelet counta (×109/mL)

31 (17–46)

48 (27–84)

<0.001

 INRb

1.5 (1.2–1.8)

1.4 (1.2–1.6)

0.147

 Antithrombinb (kIU/L)

0.90 (0.78–1.06)

0.93 (0.82–1.09)

0.542

 Fibrinogena (g/L)

2.8 (1.5–4.3)

2.7 (1.6–3.8)

0.814

 v-Lactateb (mmol/L)

4.7 (3.0–9.7) (4 missing, 7%)

3.7 (2.7–7.7) (22 missing, 11%)

0.174

Blood gas analysis

 Arterialc

  a-pH

7.26 (7.18–7.33) (16 missing, 30%)

7.25 (7.16–7.34) (51 missing, 26%)

0.703

  PaCO2 (kPa)

6.90 (6.10–7.65) (17 missing, 31%)

7.27 (6.00–9.90) (50 missing, 25%)

0.481

  PaO2 (kPa)

7.39 (6.36–8.81) (16 missing, 30%)

7.34 (6.17–9.00) (50 missing, 25%)

0.661

 Venous

  v-pHa

7.22 (7.17–7.26) (4 missing, 7%)

7.23 (7.17–7.28) (22 missing, 11%)

0.184

  PvCO2 (kPa)b

7.80 (7.38–8.95) (4 missing, 7%)

8.04 (7.25–9.00) (22 missing, 11%)

0.890

  PvO2 (kPa)a

4.30 (3.73–4.80) (4 missing, 7%)

4.46 (4.00–5.00) (22 missing, 11%)

0.105

  1. Values are expressed as median (interquartile range) or numbers (proportion)
  2. Italicized text in the p value column indicates a statistically significant correlation (p < 0.05)
  3. Abbreviations: ICH intracranial hemorrhage, INR international normalized ratio
  4. aLowest value during ECMO support and before ICH diagnosis (if applicable)
  5. bHighest value during ECMO support and before ICH diagnosis (if applicable)
  6. cRegistered within 2 h before cannulation