C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients

Table 2 Correlations of CT-proET-1 with clinical scores and other laboratory markers

	All patients
	r	p
Markers of inflammation
CRP	0.416	<0.001
Procalcitonin	0.343	0.005
IL6	0.172	0.027
Markers of organ dysfunction
Cystatin C	0.624	<0.001
GFR	−0.534	<0.001
ALT	−0.165	0.016
Bilirubin	0.148	0.031
Prothrombin time	−0.220	0.001
Albumin	−0.321	<0.001
Urea	0.577	<0.001
NTproBNP	0.505	<0.001
Clinical scores
APACHE-II	0.239	0.001
SOFA	0.136	n.s.
SAPS 2	0.400	<0.001
New and experimental biomarkers
Resistin	0.449	<0.001
NTproCNP	0.604	<0.001
suPAR	0.529	<0.001

Abbreviations: ALT alanine aminotransferase, APACHE Acute Physiology and Chronic Health Evaluation, ALT alanine aminotransferase, CRP C-reactive protein, GFR glomerular filtration rate, IL6 interleukin 6, NTproBNP amino-terminal propeptide of brain natriuretic peptide, NTproCNP, amino-terminal propeptide of C-type natriuretic peptide, SAPS Simplified Acute Physiology Score, SOFA sequential organ failure assessment, suPAR soluble urokinase plasminogen activator receptor, n.s. not significant

ISSN: 2052-0492