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Table 1 Patients’ characteristics

From: Renal replacement therapy neutralizes elevated MIF levels in septic shock

  Total (n = 25) No CRRT (n = 14) CRRT (n = 11) P value
Age (years) 73 ± 3 74 ± 4 73 ± 4 0.7946
Male (%) 80 85 72 0.5127
APACHE II 26 ± 2 25 ± 2 28 ± 3 0.4645
SAPS II 41 ± 2 39 ± 3 43 ± 3 0.4815
SOFA 9 ± 1 9 ± 1 9 ± 1 0.7636
Mechanical ventilation (%) 76 79 73 0.7872
Need for vasopressors (%) 100 100 100 1
Sites of infection (%)     
 Lung 72 86 55 0.0849
 Urogenital 16 14 18 0.7350
 Other 12 7 27 0.7341
Microbiological data (n)     
 Gram-negative/positive 3/7 3/4 0/3 0.4750
Blood urea nitrogen (mg/dl) 77 ± 8 70 ± 9 86 ± 14 0.3497
Creatinine (mg/dl) 1.8 ± 0.2 1.4 ± 0.2 2.5 ± 0.2 <0.01
WBC (/μl) 11.7 ± 1.4 11.9 ± 2 11.4 ± 2 0.8834
CRP (mg/dl) 16.8 ± 2.6 21 ± 4 12 ± 2 0.1447
PCT (ng/ml) 8.7 ± 3.4 7.8 ± 2.5 10.4 ± 8.8 0.4982
Co-morbidities (%)     
 Coronary artery disease 28 33 18 0.3895
 NYHA IV 4 0 9 0.2496
 COPD 27 24 9 0.0620
 Pulmonary hypertension 8 7 9 0.8586
 Immunosuppression 23 21 27 0.7341
 Hepatic disease 8 7 9 0.8586
Reasons for CVVHD (%)     
 Anuria/oliguria    81  
 Hyperkalemia    18  
 Acidosis    18