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Table 3 Multivariable logistic regression analysis of the training set (N = 4321) for Critical Care Trauma Center (CCTC) and Medical-Surgical Intensive Care Unit (MSICU) at London Health Sciences Center (LHSC)

From: To develop a regional ICU mortality prediction model during the first 24 h of ICU admission utilizing MODS and NEMS with six other independent variables from the Critical Care Information System (CCIS) Ontario, Canada

  Beta (β) coefficient Wald chi-square Odds ratio (95 % CI) p value
Intercept −5.18 137.10 <.0001
Age     <.0001
 0–39 (reference)
 40–79 0.80 25.73 2.23 (1.64–3.04)  
 ≥80 1.71 90.17 5.51 (3.87–7.84)  
Sex     0.44
 Male (reference)
 Female 0.06 0.60 1.07 (0.91–1.25)  
Nine Equivalents Nursing Manpower Use Score (NEMS)     <.0001
 0–22 (reference)
 23–29 0.39 4.79 1.48 (1.04–2.10)  
 ≥30 1.02 36.57 2.77 (1.99–3.84)  
Multiple Organ Dysfunction Score (MODS)     <.0001
 0 (reference)  
 1–4 1.18 9.87 3.25 (1.56–6.78)  
 5–8 1.91 26.24 6.78 (3.26–14.09)  
 9–12 2.90 57.39 18.09 (8.55–38.25)  
 ≥13 3.56 65.11 35.16 (14.81–83.46)  
ICU Admission Source     <.0001
 Operating room/post-anesthesia care unit (reference)  
 Other sourcea 0.98 28.56 2.66 (1.86–3.81)  
 Emergency department 1.00 48.76 2.71 (2.05–3.59)  
 Hospital—outside or within LHIN 1.12 58.76 3.05 (2.26–4.12)  
 Unit/ward 1.60 115.846 4.93 (3.69–6.59)  
ICU admission diagnosis     <.0001
 Cardiovascular/cardiac/vascular (reference)
 Other diagnosisb −0.81 37.67 0.45 (0.34–0.58)  
 Gastrointestinal −0.80 20.16 0.45 (0.32–0.64)  
 Respiratory −0.56 22.85 0.57 (0.45–0.72)  
 Trauma −0.32 2.52 0.73 (0.49–1.08) 0.11
 Neurological 0.002 0.0002 1.00 (0.76–1.33) 0.99
Re-admission to ICU (same hospital admission) −0.30 4.02 0.74 (0.56–0.99) 0.04
Modified Charlson’s Comorbidity Index (CCI)     0.1
 0 (reference)
 1–3 −0.21 4.20 0.81 (0.66–0.99)  
 >3 0.05 0.10 1.06 (0.76–1.48)  
  1. aOther Source includes patients admitted from the following locations:home—within or outside LHIN, level 2 unit or step-down unit, level 3 unit (medical/surgical or specialty unit), complex continuing care facility, rehabilitation facility, outside province, other
  2. bOther diagnosis includes patients with the following diseases: metabolic/endocrine, genitourinary, musculoskeletal, skin, oncology, hematology, other