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Table 4 In-hospital advanced treatments, drug administrations, and arterial blood gases by the type of first documented rhythm at EMS arrival

From: Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan

  Total First documented rhythm at EMS arrival  
VF/pulseless VT PEA/Asystole Others P
(n = 657) (n = 77) (n = 512) (n = 68)
Defibrillation, n (%) 69 (10.5) 29 (37.7) 32 (6.3) 8 (11.8) <0.001
Tracheal intubation, n (%)          0.013
 Yes 449 (68.3) 61 (79.2) 334 (65.2) 54 (79.4)  
 Intubated by EMS personnel in prehospital settings 148 (22.5) 14 (18.2) 126 (24.6) 8 (11.8)  
 No 60 (9.1) 2 (2.6) 52 (10.2) 6 (8.8)  
Extracorporeal life support, n (%) 20 (3.0) 13 (16.9) 6 (1.2) 1 (1.5) <0.001
Intra-aortic balloon pumping, n (%) 19 (2.9) 12 (15.6) 5 (1.0) 2 (2.9) <0.001
Coronary angiography, n (%) 42 (6.4) 31 (40.3) 8 (1.6) 3 (4.4) <0.001
Percutaneous coronary intervention, n (%) 23 (3.5) 17 (22.1) 5 (1.0) 1 (1.5) <0.001
Target temperature management, n (%) 61 (9.3) 34 (44.2) 23 (4.5) 4 (5.9) <0.001
Drug administration during cardiac arrest (multiple choice)          
 Adrenaline, n (%) 546 (83.1) 57 (74.0) 436 (85.2) 53 (77.9) 0.021
 Amiodarone, n (%) 10 (1.5) 9 (11.7) 1 (0.2) 0 (0.0) <0.001
 Nifekalant, n (%) 11 (1.7) 8 (10.4) 3 (0.6) 0 (0.0) <0.001
 Lidocaine, n (%) 13 (2.0) 9 (11.7) 3 (0.6) 1 (1.5) <0.001
 Atropine, n (%) 15 (2.3) 6 (7.8) 8 (1.6) 1 (1.5) 0.003
 Magnesium, n (%) 13 (2.0) 9 (11.7) 3 (0.6) 1 (1.5) <0.001
 Vasopressin, n (%) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)  
Arterial blood gases at hospital arrival, mean (SD)a          
 pH 6.93 (0.19) 7.02 (0.18) 6.91 (0.19) 7.01 (0.19) <0.001
 PaCO2 (mmHg) 86.1 (37.8) 69.8 (30.6) 91.0 (38.2) 70.1 (33.1) <0.001
 PaO2 (mmHg) 79.3 (107.3) 126.0 (138.9) 71.6 (98.6) 79.7 (112.8) <0.001
 HCO3 (mEq/l) 16.1 (5.6) 16.4 (4.8) 16.2 (5.7) 15.1 (5.3) 0.342
 Base excess (mEq/l) -16.4 (7.5) -14.6 (7.8) -16.8 (7.5) -15.2 (6.9) 0.020
 Lactate (mmol/l) 13.2 (5.4) 11.1 (4.7) 13.8 (5.4) 11.9 (5.3) <0.001
 Glucose (mg/dl) 223 (126) 265 (113) 219 (125) 206 (137) 0.007
Laboratory data at hospital arrival, mean (SD)a          
 Blood urea nitrogen (mg/dl) 25.3 (21.9) 20.6 (11.1) 24.3 (18.2) 39.8 (42.7) <0.001
 Creatinine (mg/dl) 1.4 (1.2) 1.3 (1.1) 1.4 (1.2) 1.7 (1.2) 0.139
 Total protein (g/dl) 6.0 (1.0) 6.1 (1.0) 6.0 (1.0) 5.8 (1.3) 0.320
 Albumin (g/dl) 3.1 (0.7) 3.3 (0.7) 3.0 (0.7) 3.0 (0.9) 0.019
 Sodium (mEq/l) 139.9 (7.7) 139.7 (4.9) 139.8 (8.4) 140.7 (4.5) 0.723
 Potassium (mEq/l) 6.3 (2.8) 4.5 (1.3) 6.7 (2.9) 5.6 (2.1) <0.001
 Ammonia (μg/dl) 283.8 (287) 128 (114) 325 (307) 195 (215) 0.025
  1. EMS emergency medical service, SD standard deviation
  2. aCalculated only for patients with gases or data