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Table 1 Baseline characteristics of the study population

From: Sodium bicarbonate prophylactic therapy in the prevention of contrast-induced nephropathy in patients admitted to the intensive care unit of a teaching hospital: a retrospective cohort study

Variable Total number of CT* scans (n = 211) No prophylaxis (n = 163) Prophylaxis (n = 48) p value
Male gender 125 (59.2 %) 99 (60.7 %) 26 (54.2 %) 0.42
Age (years) 65.3 (12.5) 64.3 (12.6) 68.6 (11.5) 0.04
Baseline sCr (μmol/L) 77.7 (71.5) 73.0 (53.0) 104.5 (134.0) < 0.01
Baseline GFR$ (mL/min) 68.6 (37.9) 73.6 (38.4) 51.8 (31.0) < 0.01
§APACHE II score 20.4 (8.3) 20.5 (8.5) 20.0 (7.5) 0.70
APACHE IV score 79.5 (30.1) 78.6 (31.6) 82.5 (24.4) 0.43
Predicted in-hospital mortality (%) 35.6 % (24.2 %) 34.4 (25.0) 39.8 (21.2 %) 0.18
SOFA# day 1 5.0 (6.0) 6.5 (5.0) 5.0 (5.0) 0.07
SOFA day 4 6.0 (5.0) 6.0 (7.0) 4.0 (5.0) 0.02
Comorbidities     
 Diabetes 32 (15.2 %) 31 (19.0 %) 1 (2.1 %) < 0.01
 Heart failure 11 (5.2 %) 6 (3.7 %) 5 (10.4 %) 0.09
 Sepsis 56 (26.5 %) 42 (25.8 %) 14 (29.2 %) 0.64
Haemoglobin < 6 (mmol/L) 57 (27.0 %) 42 (25.8 %) 15 (31.3 %) 0.45
Fluid balance 2529 (4701) 2401 (4639) 3123 (5695) 0.54
Patients receiving norepinephrine 54 (25.6 %) 43 (26.4 %) 11 (22.9 %) 0.63
Patients receiving aminoglycosides 12 (5.7 %) 10 (6.1 %) 2 (4.2 %) 1.00
  1. Dichotomous data are noted as the number of CT scans with the presence of the concerning variable in that group (percentage of the total number of CTs). Continuous data are noted as the mean (standard deviation) or median (interquartile range)
  2. * CT computed tomography, $ GFR glomerular filtration rate, sCr serum creatinine level, § APACHE Acute Physiology and Chronic Health Evaluation,# SOFA Sequential Organ Failure Assessment